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Liver Cancer (Hepatocellular Carcinoma) clinical trials in Durham, NC

8 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Durham VA Medical Center, Durham
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #12, Durham
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.

RecruitingPhase 1/2
  • Duke Cancer Center - Investigational Chemotherapy Service, Durham
  • Duke Cancer Center, Durham
  • Duke University - Main Hospital and Clinics, Durham
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07227012

National Liver Cancer Screening Trial

RecruitingPhase 4
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Duke University, Durham
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

RecruitingPhase 3
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07166406

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

Recruiting
  • Durham VA Medical Center, Durham, NC, Durham
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chapel Hill · 10 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Liver Cancer (Hepatocellular Carcinoma) trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.