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Blood Cancers clinical trials in Chicago, IL

15 studies for Blood Cancers are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

RecruitingPhase 3
  • The University of Chicago ( Site 0020), Chicago
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT03486873

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mount Sinai Hospital Medical Center, Chicago
  • John H Stroger Jr Hospital of Cook County, Chicago
  • University of Illinois, Chicago
  • and 1 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects

RecruitingObservational study
  • Swedish Covenant Hospital, Chicago
  • Advocate Illinois Masonic Medical Center, Chicago
All ages · All sexes · Updated Sep 17, 2026 · NCT04242095

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

RecruitingPhase 1
  • Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT06001788

Tempus Open Link for Individual Voices in Innovative Analytics Registry: Platform Protocol for Multimodal Real-World Evidence in Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Tempus AI, Chicago
All ages · All sexes · Updated Aug 10, 2026 · NCT07756034

Mosaic Trial for Stem Cell Transplant Recipients

Recruiting
  • Northwestern University Feinberg School of Medicine, Chicago
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT06960993

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

RecruitingObservational study
  • Northwestern Memorial Hospital, Chicago
  • Rush University Medical Center, Chicago
  • University of Illinois at Chicago, Chicago
  • and 2 more
All ages · All sexes · Updated Jul 6, 2026 · NCT01351545

An Extension Study for Patients Previously Enrolled in Studies With Pelabresib

RecruitingPhase 3
  • Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Jun 11, 2026 · NCT06401356

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

RecruitingPhase 1
  • University of Chicago, Chicago
Ages 13 and older · All sexes · Updated May 5, 2026 · NCT04771572

CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

RecruitingPhase 1/2
  • Northwestern Memorial Hospital, Chicago
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT03328078

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

RecruitingPhase 1
  • Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT05735184

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

Recruiting
  • University of Chicago Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Feb 20, 2026 · NCT05745285

Study to Evaluate the Pharmacokinetics and Safety of Pralatrexate in Patients With Advanced Solid Tumor or Hematological Malignancy and Either Normal Hepatic Function or Mild, Moderate, or Severe Hepatic Impairment

RecruitingPhase 1
  • Northwestern University - Feinberg School of Medicine, Chicago
Ages 18 and older · All sexes · Updated Feb 11, 2026 · NCT07036133

MPN PROGRESSion Registry: Observational Study Tracking Symptoms, Treatments, and Disease Progression in People With Myeloproliferative Neoplasms (MPNs)

RecruitingObservational study
  • MPN Research Foundation, Chicago
Ages 18 and older · All sexes · Updated Jan 23, 2026 · NCT07362225

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

RecruitingPhase 1
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Ages 1 to 21 · All sexes · Updated Dec 6, 2024 · NCT05476770

Blood Cancers trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.