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Colorectal Cancer clinical trials in Los Angeles, CA
59 studies for Colorectal Cancer are looking for participants at sites in and around Los Angeles (within about 30 miles). Open a study to see who can join and how to contact the study team.
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A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer
RecruitingPhase 2
- START Los Angeles, Los Angeles
- Valkyrie Clinical Trials (contact for more locations), Los Angeles
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
RecruitingPhase 1/2
- UCLA Jonsson Comprehensive Cancer Center, Los Angeles
- USC Norris Comprehensive Cancer Center, Los Angeles
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial
RecruitingPhase 2
- Cedars-Sinai Medical Center, Los Angeles
Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors
RecruitingPhase 1
- University of California Los Angeles, Los Angeles
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
RecruitingPhase 1/2
- Ellison Medical Institute, Los Angeles
- Valkyrie Clinical Trials, Los Angeles
- University of California Los Angeles, Los Angeles
A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
RecruitingPhase 1
- Research Site, Los Angeles
Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
RecruitingPhase 1/2
- USC Norris Comprehensive Cancer Center, Los Angeles
A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
RecruitingPhase 1/2
- UCLA ( Site 0317), Los Angeles
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
RecruitingPhase 3
- USC Norris Comprehensive Cancer Center, Los Angeles
A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer
RecruitingPhase 1/2
- University of California, Los Angeles UCLA, Los Angeles
Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
RecruitingPhase 1
- Research Site, Los Angeles
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
RecruitingPhase 3
- USC Norris Comprehensive Cancer Center, Los Angeles
A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors
RecruitingPhase 1
- START Los Angeles, Los Angeles
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
RecruitingPhase 1/2
- University of Southern California, Los Angeles
Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer
RecruitingPhase 1
- USC / Norris Comprehensive Cancer Center, Los Angeles
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
RecruitingPhase 2/3
- USC/Norris Comprehensive Cancer Center, Los Angeles
Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)
RecruitingPhase 2
- Research Site, Los Angeles
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
RecruitingPhase 1/2
- Cedars-Sinai Cancer at Cedars-Sinai Medical Center, Los Angeles
- UCLA Hematology/Oncology- Santa Monica, Los Angeles
Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
RecruitingPhase 1/2
- The Angeles clinic - A cedars SINAI AFFILIATE, Los Angeles
- USC Norris Comprehensive Cancer Center, Los Angeles
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
RecruitingPhase 3
- University of California Los Angeles Health, Los Angeles
A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
RecruitingPhase 1
- Cedars-Sinai Medical Center, Los Angeles
- UCLA, Los Angeles
A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
RecruitingPhase 1
- USC/Norris Comprehensive Cancer Center, Los Angeles
Personalized Health Self-Management Training for Colorectal Cancer Survivors
Recruiting
- University of Southern California, Los Angeles
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
RecruitingPhase 3
- Clinical Study Site, Los Angeles
- Clinical Study Site, Los Angeles
- Clinical Study Site, Los Angeles
FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors
RecruitingPhase 1
- University of Southern California, Los Angeles
A Clinic-wide Intervention (Primary Care-GI Connect) for Improving Rates of Colonoscopy After Abnormal Fecal Immunochemical Test Result in Patients at Federally Qualified Health Centers
RecruitingHealthy volunteers welcome
- University of California at Los Angeles, Los Angeles
- UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer
RecruitingPhase 1
- UCLA, Los Angeles
- Valkyrie Clinical Trials, Los Angeles
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
RecruitingPhase 1/2
- Children's Hospital Los Angeles, Los Angeles
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
RecruitingPhase 2
- Research Site, Los Angeles
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- University of California, Los Angeles (UCLA), Los Angeles
A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors
RecruitingPhase 1
- ULCA, Los Angeles
A Study of MGC026 in Participants With Advanced Solid Tumors
RecruitingPhase 1
- The Angeles Clinic and Research Institute, Los Angeles
A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
RecruitingPhase 1/2
- Los Angeles Cancer Network, Los Angeles
A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
RecruitingPhase 1/2
- GSK Investigational Site, Los Angeles
Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors
RecruitingPhase 1/2
- USC Norris Comprehensive Cancer Center, Los Angeles
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- USC Norris Comprehensive Cancer Center, Los Angeles
AMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid Tumors
RecruitingPhase 1
- University of California Los Angeles, Los Angeles
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
RecruitingPhase 1
- University of California LA, Los Angeles
A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
RecruitingPhase 3
- Los Angeles Hematology Oncology Medical Group, Los Angeles
A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
RecruitingPhase 2
- USC Norris Comprehensive Cancer Center, Los Angeles
Safely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing Chemotherapy
RecruitingPhase 2
- Cedars-Sinai Medical Center, Los Angeles
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
RecruitingPhase 2
- USC Norris Comprehensive Cancer Center /ID# 274550, Los Angeles
A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer
RecruitingPhase 4
- University of Southern California, Los Angeles
A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
RecruitingPhase 1/2
- USC Norris Comprehensive Cancer Center, Los Angeles
A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation
RecruitingPhase 1
- Cedars-Sinai Medical Center, Los Angeles
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- UCLA Medical Center, Los Angeles
KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
RecruitingPhase 1
- University of Southern California, Los Angeles
- Cedars-Sinai Medical Center, Los Angeles
- UCLA Department of Medicine, Los Angeles
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
RecruitingPhase 1/2
- UCLA Medical Center, Los Angeles
Confronting Cancer as a Community
Recruiting
- Los Angeles County-USC Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
BBO-11818 in Adult Subjects With KRAS Mutant Cancer
RecruitingPhase 1
- The Angeles Clinic and Research Institute - West Los Angeles Office, Los Angeles
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
RecruitingPhase 1/2
- Cedars-Sinai Medical Center, Los Angeles
An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.
RecruitingPhase 2
- NGM Clinical Study Site, Los Angeles
- NGM Clinical Study Site, Los Angeles
Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)
RecruitingPhase 2
- USC/Norris Cancer Center, Los Angeles
Community Partnership for Telehealth Solutions to Convey Information and Enhance Care
Recruiting
- AltaMed Health Services Corporation, Los Angeles
Botensilimab Plus Balstilimab and Fasting Mimicking Diet Plus Vitamin C for Patients With KRAS-Mutant Metastatic Colorectal Cancer
RecruitingPhase 1
- Los Angeles General Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
Improving Colonoscopy Surveillance for Patients With High Risk Colon Polyps
RecruitingHealthy volunteers welcome
- UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
RecruitingPhase 1/2
- UCLA Medical Center, Los Angeles
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
RecruitingPhase 1
- Keck School of Medicine of USC, Los Angeles
- UCLA, Los Angeles
ColoCare Study - Colorectal Cancer Cohort
RecruitingObservational study
- Cedars-Sinai Medical Center, Los Angeles
About Colorectal Cancer
Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.
More about Colorectal Cancer on MedlinePlus
Colorectal Cancer trials in other cities
- Houston, TX102 studies
- New York City, NY78 studies
- Nashville, TN69 studies
- Boston, MA63 studies
- Arlington, VA52 studies
- St. Louis, MO50 studies
- San Antonio, TX46 studies
- Philadelphia, PA44 studies
- Grand Rapids, MI40 studies
- Baldwin Park, CA37 studies
- Chicago, IL34 studies
- Tampa, FL34 studies
Other studies in Los Angeles
- Non-Small Cell Lung Cancer87 studies
- Cancer (all types)74 studies
- Breast Cancer73 studies
- Prostate Cancer61 studies
- Metastatic Cancer57 studies
- Ovarian Cancer50 studies
- Lung Cancer45 studies
- Head and Neck Squamous Cell Carcinoma42 studies
- Pancreatic Cancer35 studies
- Endometrial Cancer34 studies
- Melanoma34 studies
- Triple-Negative Breast Cancer27 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.