Home › Metastatic Cancer › Minnesota › Rochester
Metastatic Cancer clinical trials in Rochester, MN
31 studies for Metastatic Cancer are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial
RecruitingPhase 2
- Mayo Clinic in Rochester, Rochester
Adding Spatially Fractionated Radiation Therapy to Standard Palliative Radiation for Improving Disease-Related Symptoms in Patients With Unresectable Solid Tumors
Recruiting
- Mayo Clinic in Rochester, Rochester
SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial
RecruitingPhase 2
- Mayo Clinic in Rochester, Rochester
PRE-ISPY Phase I/II Oncology Platform Program
RecruitingPhase 1/2
- Mayo Clinic Comprehensive Cancer Center, Rochester
Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine Tumors
RecruitingPhase 2/3
- Mayo Clinic, Rochester
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
RecruitingPhase 3
- Mayo Clinic Hospital, Methodist Campus, Research Pharmacy, Rochester
- Mayo Clinic Pharmacy, Rochester
- Mayo Clinic Cancer Center Outpatient Pharmacy, Rochester
- and 3 more
A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
RecruitingPhase 1
- Mayo Clinic Rochester, Rochester
ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer
RecruitingPhase 2
- Mayo Clinic Cancer Center, Rochester
A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue
RecruitingPhase 2/3
- Mayo Clinic Cancer Center Outpatient Pharmacy, Rochester
- Mayo Clinic, Rochester
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
RecruitingPhase 3
- Mayo Clinic in Rochester, Minnesota, Rochester
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
RecruitingPhase 3
- Mayo Clinic in Rochester, Minnesota, Rochester
A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)
RecruitingPhase 2
- Mayo Clinic Rochester, Rochester
Symbiotic-GU-08: A Study to Learn About the Medicine Called PF-08634404 Dosed Alone and in Combination With Other Anticancer Therapies in Adults With Locally Advanced or Metastatic Renal Cell Cancer
RecruitingPhase 1/2
- Mayo Clinic Hospital, Methodist Campus, Research Pharmacy, Rochester
- Mayo Clinic Cancer Center Outpatient Pharmacy, Rochester
CREO - Microwave Ablation Feasibility Study
Recruiting
- Mayo Clinic Rochester, Rochester
Testing the Combination of DS-8201a and Olaparib in HER2-Expressing Cancers With Expansion in Patients With Platinum Resistant Ovarian Cancer
RecruitingPhase 1
- Mayo Clinic in Rochester, Rochester
Study of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.
RecruitingPhase 3
- Mayo Clinic-Comprehensive Cancer Center-Breast Clinic, Rochester
A Study to Evaluate KIN-2787 in Participants With BRAF and/or NRAS Mutation Positive Solid Tumors
RecruitingPhase 1
- Mayo Clinic - Rochester, Rochester
A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
RecruitingPhase 2
- Research Site, Rochester
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Mayo Clinic, Rochester
A Study to Investigate Safety and Effectiveness of CRN09682 in Participants With SST2-Expressing NENs and Other Solid Tumors
RecruitingPhase 1/2
- Crinetics Study Site, Rochester
A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- Mayo Clinic (Minnesota), Rochester
A Clinical Study of KTX-2001 in Subjects With Metastatic Castration-Resistant Prostate Cancer (STRIKE-001)
RecruitingPhase 1
- Mayo Clinic, Rochester
Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types
RecruitingObservational study
- Mayo Clinic in Rochester, Rochester
Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients
Recruiting
- Mayo Clinic in Rochester, Rochester
Examining Blood and Tissue Samples to Identify Diagnostic Markers in Patients With Metastatic Cancer Undergoing Tumor Removal
RecruitingObservational study
- Mayo Clinic in Rochester, Rochester
Placebo-Controlled Trial of IFx-Hu2.0 Followed By Pembrolizumab In Checkpoint Inhibitor Naïve Participants With Advanced Or Metastatic Merkel Cell Carcinoma
RecruitingPhase 2/3
- Mayo Clinic Comprehensive Cancer Center, Rochester
A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma
RecruitingPhase 2/3
- Mayo Clinic Rochester, Rochester
Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform
RecruitingObservational study
- Mayo Clinic in Rochester, Rochester
Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen
RecruitingPhase 3
- Mayo Clinic - Rochester, Mn, Rochester
Highly Selective CDK7 Inhibitor Q901 in Selected Advanced Solid Tumors
RecruitingPhase 1/2
- Mayo Clinic, Rochester
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
RecruitingPhase 1/2
- Mayo Clinic in Minnesota, Rochester
Metastatic Cancer trials in other cities
- Houston, TX104 studies
- New York City, NY93 studies
- Nashville, TN70 studies
- Boston, MA63 studies
- Los Angeles, CA57 studies
- St. Louis, MO54 studies
- Arlington, VA53 studies
- Philadelphia, PA46 studies
- Chicago, IL45 studies
- San Antonio, TX44 studies
- Washington, DC43 studies
- Dallas, TX42 studies
Other studies in Rochester
- Breast Cancer42 studies
- Non-Small Cell Lung Cancer37 studies
- Cancer (all types)30 studies
- Ovarian Cancer29 studies
- Colorectal Cancer29 studies
- Multiple Myeloma24 studies
- Heart Failure22 studies
- Prostate Cancer22 studies
- Pancreatic Cancer22 studies
- Endometrial Cancer20 studies
- Lung Cancer20 studies
- Chronic Lymphocytic Leukemia18 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.