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Pancreatic Cancer clinical trials in Boston, MA

43 studies for Pancreatic Cancer are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Research Site, Boston
Ages 18 to 130 · All sexes · Updated Oct 5, 2026 · NCT05417594

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

RecruitingPhase 1
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

Distance-Based Exercise to Preserve Function and Prevent Disability

Recruiting
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

RecruitingPhase 1
  • Brigham and Women's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, Boston
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 3
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute (DFCI), Boston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07252232

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

RecruitingPhase 3
  • Investigative Site US022, Boston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07522073

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

RecruitingObservational study
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06271291

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • Massachusetts General Hospital - Main Campus, Boston
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

RecruitingPhase 1
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

RecruitingPhase 2
  • Local Institution - 0124, Boston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

RecruitingObservational study
  • Boston Children's Hospital, Boston
Up to age 17 · All sexes · Updated Sep 11, 2026 · NCT06651580

Resilience and Equity in Aging, Cancer, and Health (REACH)

Recruiting
  • Dana-Farber Cancer Institute, Boston
Ages 65 and older · All sexes · Updated Sep 10, 2026 · NCT04674267

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

RecruitingPhase 2
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07644559

Pancreatic Cancer Early Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

A Study of PT0511 in Participants With KRAS Mutated or Amplified Advanced Solid Tumors

RecruitingPhase 1
  • Dana-Farber/Massachusetts General Hospital, Inc, Boston
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT07300150

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • Mass General Brigham Cancer Institute at Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site, Boston
  • Research Site, Boston
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of CX-5461 in Patients With Solid Tumours and BRCA1/2, PALB2 or Homologous Recombination Deficiency (HRD) Mutation

RecruitingPhase 1
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT04890613

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

RecruitingEarly phase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated May 29, 2026 · NCT06122896

Video Education With Result Dependent dIsclosure

Recruiting
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT05225428

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

A Study of MGC028 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Mass General Brigham, Boston
  • Dana Farber/Harvard Cancer Center, Boston
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT06723236

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

RecruitingPhase 2
  • Beth Israel Deaconess Medical Center - Division of Hematology/Oncology, Boston
Ages 18 and older · All sexes · Updated Apr 3, 2026 · NCT06850623

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury

RecruitingPhase 2
  • Massachusetts General Hospital, Boston
Ages 18 to 80 · All sexes · Updated Feb 27, 2026 · NCT04485286

Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial

Recruiting
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Feb 19, 2026 · NCT05356117

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

RecruitingPhase 2
  • Ohio State University-Telemedicine, Boston
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT06906562

The Effect of Kinisoquin™ on Thromboembolic Events in Patients With Metastatic or Locally Advanced Pancreatic Cancer

RecruitingPhase 3
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Feb 2, 2026 · NCT06861088

Feasibility of the LUM Imaging System for Detection of Gastrointestinal Cancers

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT02584244

Stereotactic Magnetic Resonance Guided Radiation Therapy

Recruiting
  • Brigham & Women's Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Nov 13, 2025 · NCT04115254

The Cancer of the Pancreas Screening-5 CAPS5)Study

RecruitingPhase 3
  • Dana Farber Cancer Center, Harvard University, Boston
Ages 18 and older · All sexes · Updated Oct 9, 2025 · NCT02000089

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

RecruitingPhase 1/2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT05941507

Confocal Laser Endomicroscopy as an Imaging Biomarker for the Diagnosis of Pancreatic Cystic Lesions

RecruitingObservational study
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Aug 22, 2025 · NCT03492151

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

RecruitingPhase 1
  • Dana Farber/Partners Cancer Care Inc, Boston
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542

About Pancreatic Cancer

The pancreas is a gland behind your stomach that produces insulin. Pancreatic cancer is hard to catch early. Find out about risk factors and symptoms.

More about Pancreatic Cancer on MedlinePlus

Pancreatic Cancer trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.