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Pancreatic Cancer clinical trials in Cleveland, OH

18 studies for Pancreatic Cancer are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Louis Stokes Cleveland VA Medical Center, Cleveland
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • University Hospitals Cleveland Medical Center, Cleveland
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

RecruitingPhase 3
  • Investigative Site US050, Cleveland
  • Investigative Site US020, Cleveland
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07522073

Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy (SBRT) in Participants With Cancer-Related Celiac Pain

RecruitingPhase 1
  • University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07117032

A Study Evaluating a New Radiation Treatment Workflow (NGDS)

Recruiting
  • University Hospital Cleveland Medical Center, Cleveland
Ages 21 and older · All sexes · Updated Sep 17, 2026 · NCT07824583

EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.

Recruiting
  • University Hospitals Cleveland Medical Center, Seidman Cancer Center, Case Comprehensive Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06263088

Is Intraperitoneal Drainage Necessary Following Distal Pancreatectomy?

RecruitingPhase 3
  • Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT05720338

Stereotactic Adaptive Radiation Therapy of Borderline Resectable Pancreatic Cancer an Individualized Approach

Recruiting
  • UH Cleveland Medical Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT05764720

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

RecruitingPhase 2
  • Ohio State University-Telemedicine, Cleveland
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT06906562

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Cleveland Clinic, Cleveland
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

JAB-23E73 in Adult Participants With Advanced Solid Tumors With KRAS Alteration

RecruitingPhase 1/2
  • Cleveland Clinic Foundation, Cleveland
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT06973564

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Mayfield Heights · 12 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

The Cancer of the Pancreas Screening-5 CAPS5)Study

RecruitingPhase 3
  • Case Comprehensive Cancer Center, Case Western Medical Reserve, Cleveland
Ages 18 and older · All sexes · Updated Oct 9, 2025 · NCT02000089

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #7, Cleveland
Ages 18 and older · All sexes · Updated Sep 5, 2025 · NCT05932862

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

RecruitingPhase 1
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542

Early Diagnosis of Pancreatic Cancer Duodenal Fluid-Based Biomarker Exploratory Study

RecruitingObservational studyHealthy volunteers welcome
  • Cleveland Clinic, Cleveland
Ages 19 and older · All sexes · Updated Jun 22, 2025 · NCT07030348

About Pancreatic Cancer

The pancreas is a gland behind your stomach that produces insulin. Pancreatic cancer is hard to catch early. Find out about risk factors and symptoms.

More about Pancreatic Cancer on MedlinePlus

Pancreatic Cancer trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.