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Heart Failure clinical trials in Cleveland, OH
31 studies for Heart Failure are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.
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Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
RecruitingPhase 2/3
- Cleveland Clinic-Cleveland Clinic Chidren's ( Site 0022), Cleveland
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
RecruitingPhase 3
- VA Northeast Ohio Healthcare System, Cleveland
Left vs Left Randomized Clinical Trial
Recruiting
- The MetroHealth System, Cleveland
- Cleveland Clinic, Cleveland
A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
Recruiting
- Cleveland Clinic, Cleveland
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
Recruiting
- The Cleveland Clinic Foundation, Cleveland
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
RecruitingObservational study
- Cleveland, Cleveland
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
RecruitingPhase 3
- University Hospitals Cleveland Medical Center, Cleveland
- Cleveland Clinic, Cleveland
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Cleveland Clinic Children's, Cleveland
Assessment of CCM in HF With Higher Ejection Fraction
Recruiting
- Cleveland Clinic Foundation, Cleveland
Fluid Guided Heart Failure Treatment at the Cleveland Clinic
Recruiting
- The Cleveland Clinic, Cleveland
The WiSE®-UP Study (The WiSE System Utilization & Performance Study)
RecruitingObservational study
- Cleveland Clinic Foundation, Cleveland
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
RecruitingPhase 3
- Cleveland Clinic Children's, Cleveland
Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation
Recruiting
- Cleveland Clinic Foundation, Cleveland
CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
Recruiting
- Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
Alleviant ALLAY-HFrEF Study
Recruiting
- Cleveland Clinic, Cleveland
Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation
RecruitingObservational study
- Cleveland Clinic, Cleveland
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
RecruitingObservational study
- University Hospitals Cleveland Medical Center, Cleveland
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
RecruitingPhase 3
- Louis Stokes Clvlnd VA Med Ctr, Cleveland
Alleviant ALLAY-HF Study
Recruiting
- Cleveland Clinic, Cleveland
Longitudinal Validation of CIRC Technologies
RecruitingObservational studyHealthy volunteers welcome
- Cleveland Clinic, Cleveland
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
Recruiting
- University Hospital (Cleveland), Cleveland
Early Assessment and Initiation of GuideLine-Directed Evidence-Based Management-HF
RecruitingObservational study
- Cleveland Clinic, Cleveland
CV Imaging of Metabolic Interventions
RecruitingObservational studyHealthy volunteers welcome
- Cardiovascular Innovation Research Center, Cleveland
Development of CIRC Technologies
RecruitingObservational studyHealthy volunteers welcome
- Cardiovascular Innovation Research Center, Cleveland
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Recruiting
- Cleveland Clinic, Cleveland
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
RecruitingPhase 3
- Cleveland Clinic Foundation, Cleveland
A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure
Recruiting
- Cleveland Clinic, Cleveland
Open-label, Dose Escalation Study of Safety and Preliminary Efficacy of TN-401 in Adults With PKP2 Mutation-associated ARVC
RecruitingPhase 1
- Cleveland Clinic, Cleveland
Non-interventional Study of Seroprevalence of Pre-existing Antibodies Against Adenovirus-associated Virus Vector (AAV9) and the Progression of Disease in Patients With Plakophilin 2 (PKP2)-Associated Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
RecruitingObservational study
- Cleveland Clinic, Cleveland
Screening for earlY Heart Failure Diagnosis and Management in Primary Care or at HOme Using Natriuretic Peptides and echocardiographY "SYMPHONY-HF"
Recruiting
- Cleveland Clinic, Cleveland
Safety and Efficacy of ARNI After LVAD ImplanT (SEAL-IT) Study
RecruitingPhase 4
- Cleveland Clinic, Cleveland
About Heart Failure
Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.
More about Heart Failure on MedlinePlus
Heart Failure trials in other cities
- New York City, NY51 studies
- Boston, MA46 studies
- Dallas, TX42 studies
- Houston, TX35 studies
- Philadelphia, PA31 studies
- San Francisco, CA29 studies
- Chicago, IL28 studies
- Durham, NC25 studies
- Kansas City, MO25 studies
- St. Louis, MO24 studies
- Indianapolis, IN24 studies
- Atlanta, GA23 studies
Other studies in Cleveland
- Non-Small Cell Lung Cancer48 studies
- Cancer (all types)36 studies
- Breast Cancer33 studies
- Metastatic Cancer30 studies
- Prostate Cancer30 studies
- Ovarian Cancer29 studies
- Lung Cancer26 studies
- Colorectal Cancer25 studies
- Acute Myeloid Leukemia20 studies
- Head and Neck Squamous Cell Carcinoma20 studies
- Cardiovascular Disease20 studies
- Parkinson's Disease19 studies
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.