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Acute Myeloid Leukemia clinical trials in Cleveland, OH

20 studies for Acute Myeloid Leukemia are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

RecruitingPhase 2
  • Case Western Reserve University, Cleveland
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05564390

A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)

RecruitingPhase 3
  • University Hospitals Cleveland Medical Center, Cleveland
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06852222

Testing New Therapies for Patients With Acute Myeloid Leukemia Who Are Newly Diagnosed and Have Not Yet Started Treatment (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Case Western Reserve University, Cleveland
Ages 18 to 59 · All sexes · Updated Sep 22, 2026 · NCT05554406

Venetoclax and HMA Treatment of Older and Unfit Adults With FLT3 Mutated Acute Myeloid Leukemia (AML) (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Case Western Reserve University, Cleveland
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06317649

A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

RecruitingPhase 3
  • Rainbow Babies and Childrens Hospital, Cleveland
  • Cleveland Clinic Foundation, Cleveland
6 Months – 21 Years · All sexes · Updated Sep 17, 2026 · NCT04293562

Co-Transplant of an Unmodified Haplo-Identical Graft With Cord Blood

RecruitingPhase 2
  • Case Comprehensive Cancer Center, University Hospitals Cleveland Medical Center Seidman Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06904482

Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

RecruitingPhase 1/2
  • Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT03471260

Xylitol Dental Wipes for the Reduction of Bloodstream Infection Risk in Children With Acute Myeloid Leukemia

RecruitingPhase 3
  • Rainbow Babies and Childrens Hospital, Cleveland
Ages 1 to 25 · All sexes · Updated Sep 4, 2026 · NCT07022678

Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML

RecruitingPhase 1
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06533761

Safety and Tolerability of Ziftomenib Combinations in Patients With Relapsed/Refractory Acute Myeloid Leukemia

RecruitingPhase 1
  • UH Seidman Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT06001788

L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML

RecruitingPhase 2/3
  • University Hospitals Cleveland Medical Center, Cleveland
Ages 18 to 80 · All sexes · Updated Aug 5, 2026 · NCT06788756

Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT

RecruitingPhase 3
  • The Ohio State University Comprehensive Cancer Center (OSUCCC), Cleveland
Ages 18 to 75 · All sexes · Updated Jul 17, 2026 · NCT05429632

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

RecruitingObservational study
  • University Hospitals Case Medical Center, Cleveland
  • Cleveland Clinic, Cleveland
All ages · All sexes · Updated Jul 6, 2026 · NCT01351545

A Phase Ib Trial of Azacitidine, Venetoclax and Allogeneic NK Cells for Acute Myeloid Leukemia (ADVENT-AML)

RecruitingPhase 1
  • Case Western Reserve University, Cleveland
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT05834244

Decitabine and Venetoclax Treatment as Maintenance Therapy in Patients Post Allograft Stem Cell Transplant

RecruitingPhase 1/2
  • Cleveland Clinic Taussig Cancer Center, Case Comprehensive Cancer Center, Cleveland
  • University Hospitals Seidman Cancer, Case Comprehensive Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Apr 27, 2026 · NCT06129734

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

RecruitingPhase 1
  • University Hospitals Cleveland Medical Center, Cleveland
  • Cleveland Clinic Taussig Cancer Institute, Cleveland
Ages 18 and older · All sexes · Updated Mar 13, 2026 · NCT05735184

Olutasidenib for the Treatment of Patients With IDH1 Mutated AML, MDS or CMML After Donor Hematopoietic Cell Transplant

RecruitingPhase 1
  • Cleveland Clinic Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT06543381

Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring

RecruitingObservational study
  • University Hospitals Seidman Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Feb 23, 2026 · NCT05974150

About Acute Myeloid Leukemia

Acute Myeloid Leukemia (AML) is a cancer of the white blood cells. AML usually gets worse quickly if it is not treated. Read more.

More about Acute Myeloid Leukemia on MedlinePlus

Acute Myeloid Leukemia trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.