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Bladder Cancer clinical trials in Nashville, TN

31 studies for Bladder Cancer are looking for participants at sites in and around Nashville (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
  • Tennessee Oncology PLLC, Nashville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute - Pharmacy, Nashville
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499

Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)

RecruitingPhase 3
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07566156

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

RecruitingPhase 2
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382

Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
  • SCRI Oncology Partners, Nashville
  • Tennessee Oncology, PLLC - Elliston Place Plaza Medical Oncology & Hematology, Nashville
  • and 9 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07421700

A Study to Learn About the Study Medicine PF-08052667 in People With Bladder Cancer

RecruitingPhase 1
  • Urology Associates, P.C., Nashville
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07206225

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Nashville
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)

RecruitingPhase 3
  • Tennessee Oncology, PLLC - Elliston Place Plaza Medical Oncology & Hematology ( Site 0831), Nashville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07419295

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

RecruitingPhase 3
  • Sarah Cannon Research Institute, Nashville
  • SCRI Oncology Partners, Nashville
  • Tennessee Oncology, Nashville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05267626

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas

RecruitingPhase 1
  • SCRI, Nashville
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07217171

First-in-Human Trial of DS-2243a in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06644755

Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC

RecruitingPhase 2
  • Urology Associates, PC, Nashville
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06567743

Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer

RecruitingPhase 2
  • Urology Associates PC, Nashville
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT05951179

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

RecruitingPhase 1
  • Sarah Cannon and HCA Research Institute, Nashville
  • Tennessee Oncology, Nashville
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05614739

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study

RecruitingPhase 3
  • Vanderbilt Breast Center at One Hundred Oaks, Nashville
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07097142

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute Oncology Partners (SCRI-Nashville), Nashville
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT05592626

LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

RecruitingPhase 1/2
  • Urology Associates, P.C., Nashville
  • Vanderbilt Univerity Medical Center, Nashville
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT04752722

Comparison of Intravesical Therapy and Surgery as Treatment Options for Bladder Cancer 2

RecruitingObservational study
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07225127

Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

RecruitingPhase 2/3
  • SCRI Oncology Partners, Nashville
  • Local Institution - 0084, Nashville
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT07106762

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • SCRI - TriStar Medical Group Children's Specialists, Nashville
  • SCRI Oncology Partners, Nashville
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

An Open-label Study to Investigate the Efficacy and Safety of Dato-DXd + Rilvegostomig vs SoC in Adult Participants With High-risk MIUC

RecruitingPhase 3
  • Research Site, Nashville
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07720284

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • US Oncology Research LLC, Nashville
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

Recruiting
  • Vanderbilt University Medical Center, Nashville
Ages 18 to 88 · All sexes · Updated Jul 2, 2026 · NCT06394869

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI) Oncology Partners, Nashville
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Nashville
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Bladder Cancer

Bladder cancer symptoms range from lower back pain to blood in your urine. Read about important risk factors and find a list of treatments available

More about Bladder Cancer on MedlinePlus

Bladder Cancer trials in other cities

Other studies in Nashville

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.