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Cancer (all types) clinical trials in Charlotte, NC

27 studies for Cancer (all types) are looking for participants at sites in and around Charlotte (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Registry Study for Radiation Therapy Outcomes

RecruitingObservational study
  • Atrium Health Levine Cancer Proton & Advanced Radiation Center, Charlotte
All ages · All sexes · Updated Sep 29, 2026 · NCT01255748

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

RecruitingPhase 2/3
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

RecruitingPhase 1
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06150157

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

RecruitingPhase 2
  • Atrium Health's Levine Cancer Institute, Charlotte
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

RecruitingPhase 2/3
  • Levine Cancer Institute, Charlotte
All ages · All sexes · Updated Sep 18, 2026 · NCT03435796

A Study to Assess Adverse Events and Change in Disease Activity of Oral Surzetoclax Alone or in Combination With Subcutaneous and/or Oral Antimyeloma Agents in Adult Participants With Multiple Myeloma (MM)

RecruitingPhase 1/2
  • Atrium Health Levine Cancer Institute /ID# 271510, Charlotte
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06953960

A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies

RecruitingPhase 1/2
  • Research Site, Charlotte
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT05123482

A Study to Evaluate LY3537021 for the Treatment of Nausea and Vomiting Caused by Chemotherapy in Adults With Cancer

RecruitingPhase 2
  • Oncology Specialists of Charlotte, Charlotte
  • Southern Oncology Specialists, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07169851

Comprehensive Care for AYA: Needs Assessment Survey

RecruitingObservational study
  • Atrium Health Levine Cancer, Charlotte
Ages 15 and older · All sexes · Updated Aug 27, 2026 · NCT07196241

A Study of ARC-02 in B-cell NHL

RecruitingPhase 1
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07691606

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Carolinas Medical Center/Levine Cancer Institute, Charlotte
  • Novant Health Presbyterian Medical Center, Charlotte
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Role of Mitochondrial Bioenergetics in Resilience for Gynecologic Cancer

RecruitingObservational study
  • Atrium Health Levine Cancer, Charlotte
Ages 50 and older · Women · Updated Jul 30, 2026 · NCT07046936

A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving Chemotherapy

RecruitingPhase 2
  • Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Charlotte
Ages 18 to 70 · All sexes · Updated Jul 24, 2026 · NCT06866964

Patient Descriptors Of Cancer-Related Fatigue: A Mixed Methods Pilot Study Of Cancer Survivors

RecruitingObservational study
  • Levine Childrens Hospital Pediatric Cancer and Blood Disorders, Charlotte
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06634381

Immune Function and Response to Vaccination After Cancer Therapy in Pediatric Patients

RecruitingPhase 2
  • Levine Cancer Institute, Charlotte
Ages 2 to 21 · All sexes · Updated Jul 23, 2026 · NCT04948619

LCI-PED-NOS-EXER-001: Exercise in Pediatric Oncology Patients

Recruiting
  • Levine Children's Hospital, Charlotte
Ages 2 to 25 · All sexes · Updated Jul 22, 2026 · NCT05058508

A Novel Dialectical Behavior Therapy Brief Group Intervention for Cigarette Smoking by Patients With Cancer: An Open Clinical Trial

Recruiting
  • Atrium Health Levine Cancer, Charlotte
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT07119489

Resilience Enhancement Using Electronic Frailty Index-Directed Care Pathway

Recruiting
  • Levine Cancer Institute, Charlotte
Ages 65 and older · All sexes · Updated Jul 2, 2026 · NCT07175376

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Carolina BioOncology Institute, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06993844

Isa-Rd for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma

RecruitingPhase 2
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT05145400

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

RecruitingPhase 2
  • Novant Health Presbyterian Medical Center /ID# 230201, Charlotte
Ages 18 and older · All sexes · Updated Feb 9, 2026 · NCT04895436

A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Carolina BioOncology Institute, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT07317505

Trial of Nab-Sirolimus in Combination With Letrozole in Patients With Advanced or Recurrent Endometrioid Endometrial Cancer

RecruitingPhase 2
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Nov 13, 2025 · NCT05997017

Open-Label, Dose-Escalation With Expansion to Assess the Safety, Tolerability, and PK of TRE-515 in Subjects With Solid Tumors

RecruitingPhase 1
  • Carolina BioOncology Institute, Huntersville · 13 mi away
Ages 18 and older · All sexes · Updated Sep 12, 2025 · NCT05055609

A Study for Participants Previously Treated With Century Therapeutics Cellular Therapy Product

RecruitingObservational study
  • Levine Cancer Institute, Charlotte
Ages 18 and older · All sexes · Updated Jun 25, 2025 · NCT05768269

About Cancer (all types)

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Other studies in Charlotte

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.