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Myelodysplastic Syndromes clinical trials in Boston, MA

19 studies for Myelodysplastic Syndromes are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

RecruitingPhase 1
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06484062

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

RecruitingPhase 2
  • Tufts Medical Center, Boston
  • Beth Israel Deaconess Medical Center, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05564390

Ivosidenib and Venetoclax With or Without Azacitidine in Treating Patients With IDH1 Mutated Hematologic Malignancies

RecruitingPhase 1/2
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT03471260

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

RecruitingPhase 3
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06465953

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

RecruitingPhase 1Healthy volunteers welcome
  • Brigham and Women's Hospital, Boston
Ages 18 to 75 · All sexes · Updated Jul 28, 2026 · NCT07020533

A Phase 1 Trial of CIML NK Cell Infusion for Myeloid Disease Relapse After Hematopoietic Cell Transplantation

RecruitingPhase 1
  • Boston Children's Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 12 and older · All sexes · Updated Jun 17, 2026 · NCT04024761

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

RecruitingPhase 1
  • Dana-Farber Cancer Institute, Boston
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Jun 17, 2026 · NCT06138587

Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

RecruitingObservational study
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated May 7, 2026 · NCT02269592

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

RecruitingPhase 2/3
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT04256317

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

Venetoclax Basket Trial for High Risk Hematologic Malignancies

RecruitingPhase 1
  • Dana-Farber Cancer Institute, Boston
Ages 1 to 40 · All sexes · Updated Mar 12, 2026 · NCT05292664

CMV-MVA Triplex Vaccination in HLA-Matched Related Stem Cell Donors for the Prevention of CMV Infection in Patients Undergoing Hematopoietic Stem Cell Transplant

RecruitingPhase 2Healthy volunteers welcome
  • DFCI/BWH Brigham and Women's Hospital, Boston
Ages 18 to 75 · All sexes · Updated Mar 10, 2026 · NCT06059391

IS-free Treg HaploHCT

RecruitingPhase 1
  • Dana Farber Cancer Institute, Boston
Ages 18 to 75 · All sexes · Updated Oct 20, 2025 · NCT04678401

HEME Home Transfusion Program

Recruiting
  • Brigham and Women's Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 17, 2025 · NCT06487247

Study of REM-422 in Patients With AML or Higher Risk MDS

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Apr 23, 2025 · NCT06297941

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

RecruitingPhase 1
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Apr 15, 2025 · NCT06462365

About Myelodysplastic Syndromes

Myelodysplastic Syndromes (MDS) are rare. They are sometimes found during a routine blood test. Learn symptoms, risk factors, and treatment options.

More about Myelodysplastic Syndromes on MedlinePlus

Myelodysplastic Syndromes trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.