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Pancreatic Cancer clinical trials in Houston, TX

61 studies for Pancreatic Cancer are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

RecruitingPhase 1
  • UT MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614

A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)

RecruitingPhase 2
  • The University of Texas MD Anderson Cancer Center - Texas Medical Center, Houston
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06760819

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors

RecruitingPhase 1
  • University of Texas MD Anderson Cancer Center, Houston
  • The University of Texas, MD Anderson Cancer Center - West Houston, Houston
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07090499

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, Houston
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

Study of Zoldonrasib + Chemo of Investigator's Choice vs Placebo + Chemo of Investigator's Choice as First-line Treatment in Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma ( RASolute 305 )

RecruitingPhase 3
  • University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07621718

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

RecruitingPhase 1
  • MD Anderson, Houston
  • NEXT Oncology Houston, Houston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

RecruitingPhase 2/3
  • Houston Methodist Hospital, Houston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 3
  • University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07252232

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • MD Anderson, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer

RecruitingPhase 3
  • Houston Methodist Office of Graduate - Houston Methodist Neal Cancer Center at Texas Medical Center, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07409272

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • Baylor College of Medicine, Houston
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

RecruitingPhase 3
  • Investigative Site US011, Houston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07522073

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

RecruitingObservational study
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT06271291

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center - Texas Medical Center, Houston
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

RecruitingPhase 2
  • Local Institution - 0085, Houston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

CREO - Microwave Ablation Feasibility Study

Recruiting
  • Memorial Hermann-Texas Medical Center, Houston
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07817147

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

RecruitingObservational study
  • M D Anderson Cancer Center, Houston
  • Texas Children's Hospital, Houston
Up to age 17 · All sexes · Updated Sep 11, 2026 · NCT06651580

A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • UT MD Anderson, Houston
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • The University of Texas - MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

RecruitingObservational study
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
Ages 50 to 75 · All sexes · Updated Sep 4, 2026 · NCT04239573

iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation

RecruitingPhase 1/2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT03608631

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

RecruitingPhase 2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07644559

PTM-101 in Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06673017

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

RecruitingPhase 1
  • MDACC, Houston
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05245500

Alpha Radiation Emitters (DaRT) With Chemotherapy for the Treatment of Locally Advanced and Metastatic Pancreatic Cancer

Recruiting
  • Texas Oncology, Houston
  • Baylor College of Medicine, Houston
  • University Cancer and Diagnostic, Houston
Ages 18 to 120 · All sexes · Updated Aug 27, 2026 · NCT06698458

Th-1 Dendritic Cell Immunotherapy Plus Standard Chemotherapy for Pancreatic Adenocarcinoma

RecruitingPhase 1
  • Baylor College of Medicine Medical Center - McNair Campus, Houston
  • Baylor St. Lukes Medical Center, Houston
  • Dan L. Duncan Cancer Center at Baylor College of Medicine, Houston
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT04157127

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

RecruitingPhase 3
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston
  • Ben Taub General Hospital, Houston
  • Houston Methodist Hospital, Houston
  • and 4 more
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06958328

A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT07066657

Study of AZD9574 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Research Site, Houston
Ages 18 to 130 · All sexes · Updated Aug 12, 2026 · NCT05417594

A Study of MGC026 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
  • University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06242470

A Study of DM002 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • The University of Texas, MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06751329

Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 1
  • Excel Diagnostics & Nuclear Oncology Center, Houston
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT07733674

IDOV-Immune for Advanced Solid Tumors

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06910657

Neoadjuvant Folfirinox Combined With Pembrolizumab Followed by Surgery for Patients With Resectable Pancreatic Cancer

RecruitingPhase 2
  • Baylor College of Medicine, Houston
  • Baylor St. Luke's Medical Center (BSLMC)., Houston
  • Houston Methodist Hospital, Houston
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05132504

Safety and Efficacy of Endoscopic Ultrasound (EUS) Guided Radiofrequency Ablation (RFA) in the Treatment of Pancreatic Lesions

RecruitingObservational study
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT07737171

Extending Outcomes for Pancreas Cancer Patients With Nominal Oligometastatic Disease (EXPAND): A Randomized Phase III Trial

RecruitingPhase 3
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT06593431

Computed Tomography in Diagnosing Patients With Pancreatic or Hepatobiliary Cancer

Recruiting
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT02361320

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

RecruitingPhase 2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06695845

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site, Houston
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • University of Texas, MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

High Dose-Rate Brachytherapy for the Treatment of Both Primary and Secondary Unresectable Liver Malignancies

Recruiting
  • M D Anderson Cancer Center, Houston
Ages 19 and older · All sexes · Updated May 22, 2026 · NCT05053555

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Dose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT06239194

A Study of TSN1611 Treating Patients With Advanced Solid Tumors Harboring KRAS G12D Mutation

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 to 75 · All sexes · Updated Apr 24, 2026 · NCT06385925

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

RecruitingObservational study
  • Md Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

RecruitingPhase 2
  • Ohio State University-Telemedicine, Houston
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT06906562

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center (site 127), Houston
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Houston
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT05941507

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #1, Houston
Ages 18 and older · All sexes · Updated Sep 5, 2025 · NCT05932862

Confocal Laser Endomicroscopy as an Imaging Biomarker for the Diagnosis of Pancreatic Cystic Lesions

RecruitingObservational study
  • Baylor College of Medicine, Houston
Ages 18 and older · All sexes · Updated Aug 22, 2025 · NCT03492151

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 15, 2025 · NCT04429542

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

RecruitingPhase 1/2
  • The University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 1, 2025 · NCT04503265

A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jan 21, 2025 · NCT06782555

About Pancreatic Cancer

The pancreas is a gland behind your stomach that produces insulin. Pancreatic cancer is hard to catch early. Find out about risk factors and symptoms.

More about Pancreatic Cancer on MedlinePlus

Pancreatic Cancer trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.