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Rare Diseases clinical trials in Durham, NC

3 studies for Rare Diseases are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

RecruitingObservational studyHealthy volunteers welcome
  • Duke University Health System, Durham
1 Month – 100 Years · All sexes · Updated Oct 2, 2026 · NCT02450851

A Study Evaluating the Real-World Experience of Givinostat in Patients With Duchenne Muscular Dystrophy

RecruitingObservational study
  • Duke University / Lenox Baker Children's Hospital, Durham
Ages 6 and older · All sexes · Updated Jul 2, 2026 · NCT07127978

Study of S-606001 as an Add-on to Enzyme Replacement Therapy (ERT) in Participants With Late-onset Pompe Disease (LOPD)

RecruitingPhase 2
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT07123155

About Rare Diseases

A rare disease is one that affects fewer than 200,000 people in the United States. There are nearly 7,000, affecting more than 25 million Americans.

More about Rare Diseases on MedlinePlus

Rare Diseases trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.