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Brain Tumors clinical trials in Houston, TX

35 studies for Brain Tumors are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

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GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma

RecruitingPhase 1
  • Baylor St. Luke's Medical Center, Houston
Ages 21 to 70 · All sexes · Updated Sep 30, 2026 · NCT06815432

Laser Interstitial Thermal Therapy (LITT) or Surgery and Adjuvant Reirradiation for Recurrent Brain Metastases (LaSAR BeaM)

RecruitingPhase 2
  • The University of Texas M. D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07053033

A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT05048212

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

RecruitingPhase 2
  • Local Institution - 0085, Houston
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma

RecruitingPhase 2
  • Texas Children's Hospital, Houston
59 Months · All sexes · Updated Sep 15, 2026 · NCT05535166

OBSERVE: A Pilot Study Of Omission Of Brain Metastasis Stereotactic Radiosurgery Following Resection With CNS-Active Systemic Therapy

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07655583

Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology

RecruitingObservational study
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04988009

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • MD Anderson Cancer Center - University of Texas, Houston
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

A Study to Evaluate the Safety and Efficacy of Intracranial Venous Blood Sampling for Liquid Biopsy in the Diagnosis of Brain Cancers

RecruitingObservational study
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07467109

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

RecruitingPhase 1/2
  • University of Texas MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05386108

Targeted Pediatric High-Grade Glioma Therapy

RecruitingObservational study
  • Texas Children's Hospital, Houston
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

A Study of Zanzalintinib in Participants With Recurrent or Progressive Meningioma

RecruitingPhase 2
  • UT MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07428616

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

RecruitingPhase 1
  • MD Anderson Cancer Center, Houston
36 Months – 22 Years · All sexes · Updated Sep 4, 2026 · NCT03911388

Study of Olutasidenib and Temozolomide in HGG

RecruitingPhase 2
  • Texas Children's Hospital, Houston
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974

A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

RecruitingPhase 2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06764940

A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases

RecruitingPhase 1
  • The University of Texas M.D. Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06136884

Trial to Study Anti- HCMV Therapy in Breast Cancer Patients With Progressive Intracranial Metastases and CMV Infection

RecruitingPhase 2
  • Houston Methodist Neal Cancer Center, Houston
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT07383649

Study of 203Pb-RMX-VH-PIB Dosimetry and Biodistribution in Patients With Glioblastoma Multiform (GBM) and Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 1
  • Excel Diagnostics & Nuclear Oncology Center, Houston
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT07733674

C7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)

RecruitingPhase 1
  • Texas Children's Hospital, Houston
12 Months – 25 Years · All sexes · Updated Aug 3, 2026 · NCT04099797

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

RecruitingObservational study
  • Baylor St. Luke's Medical Center | Baylor College of Medicine, Houston
  • Houston Methodist Hospital, Houston
All ages · All sexes · Updated Jul 22, 2026 · NCT04427384

Hyperpolarized Carbon C 13 Pyruvate in Diagnosing Glioma in Patients With Brain Tumors

RecruitingPhase 1
  • M D Anderson Cancer Center, Houston
Ages 19 and older · All sexes · Updated Jul 16, 2026 · NCT03830151

A Phase II Study of Tucatinib and Ado-trastuzumab Emtansine (T-DM1) in Patients With HER2-positive Metastatic Solid Tumors and Metastases to Brain (TUCATEMEB)

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT05673928

Mapping of Human Cognition

Recruiting
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 to 75 · All sexes · Updated Jul 14, 2026 · NCT05989893

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

RecruitingPhase 2
  • Texas Children's Hospital, Houston
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors

Recruiting
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 20, 2026 · NCT02754544

A Comprehensive Clinical fMRI Software Solution to Enable Mapping of Critical Functional Networks and Cerebrovascular Reactivity in the Brain

RecruitingObservational study
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 20, 2026 · NCT05342454

Phase II Study of Pembrolizumab in Combination With Lenvatinib in Patients With TNBC, NSCLC, and Other Tumor Types and Brain Metastases

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT05064280

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study

RecruitingObservational study
  • Md Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT04075305

Phase II Trial of the PARP Inhibitor Niraparib and PD-1 Inhibitor Dostarlimab in Patients With Advanced Cancers With Active Progressing Brain Metastases (STARLET)

RecruitingPhase 2
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05700721

Systematic Light Exposure in Pediatric Brain Tumor Survivors

Recruiting
  • Texas Children's Hospital, Houston
Ages 10 to 18 · All sexes · Updated Sep 18, 2025 · NCT05340881

A Study of PARP1 Selective Inhibitor, EIK1004 (IMP1707) in Participants With Advanced Solid Tumors.

RecruitingPhase 1/2
  • MD Anderson, Houston
Ages 18 to 89 · All sexes · Updated Aug 19, 2025 · NCT06907043

About Brain Tumors

A brain tumor is a growth of abnormal cells in the brain tissue. Learn the types of tumors, symptoms, how they are diagnosed and treatment options.

More about Brain Tumors on MedlinePlus

Brain Tumors trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.