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Brain Tumors clinical trials in Chicago, IL

11 studies for Brain Tumors are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Frameless Stereotactic Radiosurgery for Intact Brain Metastases

RecruitingPhase 2
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02747303

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

Targeted Pediatric High-Grade Glioma Therapy

RecruitingObservational study
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
12 Months – 39 Years · All sexes · Updated Sep 8, 2026 · NCT05839379

Study of Olutasidenib and Temozolomide in HGG

RecruitingPhase 2
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Ages 12 to 39 · All sexes · Updated Sep 1, 2026 · NCT06161974

A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases

RecruitingPhase 2
  • Robert H. Lurie Comprehensive Cancer Center Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06764940

Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).

RecruitingPhase 2
  • Lurie Children's Hospital, Chicago
Ages 1 to 26 · All sexes · Updated Aug 4, 2026 · NCT07680439

REMASTer: REcurrent Brain Metastases After SRS Trial

Recruiting
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Jun 18, 2026 · NCT05124912

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

RecruitingPhase 2
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
12 Months – 39 Years · All sexes · Updated May 29, 2026 · NCT05843253

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • Northwestern Memorial Hospital, Chicago
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery

Recruiting
  • University of Illinois at Chicago, Chicago
Ages 18 to 99 · All sexes · Updated Nov 12, 2025 · NCT07111182

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

RecruitingPhase 3
  • John H Stroger Jr Hospital of Cook County, Chicago
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961

About Brain Tumors

A brain tumor is a growth of abnormal cells in the brain tissue. Learn the types of tumors, symptoms, how they are diagnosed and treatment options.

More about Brain Tumors on MedlinePlus

Brain Tumors trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.