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Colorectal Cancer clinical trials in Colorado
56 studies for Colorectal Cancer are looking for participants at sites in Colorado.
Cities in Colorado
- Aurora32 studies
- Denver23 studies
- Centennial9 studies
- Highlands Ranch8 studies
- Colorado Springs6 studies
- Longmont5 studies
- Lakewood5 studies
- Pueblo5 studies
- Westminster4 studies
- Boulder4 studies
- Thornton3 studies
- Loveland3 studies
- Greeley3 studies
Colonoscopy vs Stool Testing for Older Adults With Colon Polyps
- University of Colorado, Aurora
Recruiting
Ages 65 to 82 · All sexes · Updated Oct 2, 2026 · NCT05612347A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer
- Rocky Mountain Cancer Centers - Aurora /ID# 280112, Aurora
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07525206The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- Rocky Mountain Cancer Center, Denver
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- Rocky Mountain Regional VA Medical Center, Aurora
- UCHealth University of Colorado Hospital, Aurora
- Penrose-Saint Francis Healthcare, Colorado Springs
- and 15 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069Family Communications After Genetic Testing
- Penrose-Saint Francis Healthcare, Colorado Springs
- Rocky Mountain Cancer Centers-Penrose, Colorado Springs
- Saint Francis Cancer Center, Colorado Springs
- and 6 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
- Exelixis Clinical Site #87, Littleton
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
- Rocky Mountain Cancer Centers, LLP, Aurora
- Rocky Mountain Cancer Centers - Boulder, Boulder
- Rocky Mountain Cancer Centers, LLP, Centennial
- and 18 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800Spevatamig (PT886) as Monotherapy or in Combination With Chemo and/or Targeted Therapy and/or ICI, for the Treatment of Patients With Advanced Gastrointestinal Cancers, Including Gastric, Gastroesophageal Junction, Pancreatic Ductal or Biliary Tract Carcinomas (the TWINPEAK Study)
- Sarah Cannon Research Institute (SCRI), Denver
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05482893A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
- University of Colorado Anschutz Medical Campus ( Site 0299), Aurora
- University of Colorado Anschutz Medical Campus ( Site 0325), Aurora
- University of Colorado Anschutz Medical Campus ( Site 0326), Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06428409A Study of JNJ-89402638 for Metastatic Colorectal and Gastric Cancers
- University of Colorado Denver Anschultz Medical Campus, Aurora
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06663319A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
- University of Colorado Denver Anschultz Medical Campus, Aurora
- Rocky Mountain Cancer Centers, Denver
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06750094A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
- Rocky Mountain Cancer Centers, Denver
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06662786Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
- UCHealth University of Colorado Hospital, Aurora
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195Testing the Addition of Anti-cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment, Cetuximab Plus Encorafenib, for Colorectal Cancer
- UCHealth University of Colorado Hospital, Aurora
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06102902Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors
- University of Colorado Cancer Center, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
- University of Colorado Hospital-Anschutz Cancer Pavilion, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
- University of Colorado - Aurora Cancer Center, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors
- GSK Investigational Site, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07213609A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
- Sarah Cannon Research Institute Scri Oncology Partners, Aurora
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
- University of Colorado Cancer Center, Aurora
- Rocky Mountain Cancer Centers, LLP, Lone Tree
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT04929223A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
- Rocky Mountain Cancer Centers, LLP- Aurora, Lone Tree
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07549412Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer
- UCHealth University of Colorado Hospital, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07147231The Vanguard Study: Testing a New Way to Screen for Cancer
- Keefe Memorial Hospital, Cheyenne Wells
- Kaiser Permanente-Franklin, Denver
- Poudre Valley Hospital, Fort Collins
- and 5 more
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors
- University of Colorado, Aurora
RecruitingPhase 1
Ages 18 to 99 · All sexes · Updated Sep 1, 2026 · NCT06983743A Clinical Trial to Test if the Investigational Drug BNT329 is Safe and Potentially Beneficial for People With Advanced Solid Tumors Known to Express the Tumor Marker CA19-9
- SCRI at HCA Health One, Denver
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07186842A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer
- SCRI Denver, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT07227168Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
- Children's Hospital Colorado, Aurora
RecruitingPhase 1/2
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
- Sarah Cannon Research Institute at HealthOne, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06586515Pre- and Post-operative TEG Indices in Patients With or Without Adenocarcinoma Undergoing Surgical Resection
- University of Colorado Denver, Aurora
- UCHealth Highlands Ranch Hospital, Highlands Ranch
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 99 · All sexes · Updated Aug 24, 2026 · NCT05517811A Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.
- University of Colorado Hospital- Anschutz Cancer Center Pavillion (ACP), Aurora
- University of Colorado Cancer Center - Highlands Ranch Hospital, Highlands Ranch
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT07235293Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients
- University of Colorado Anschutz Medical Center, Aurora
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT05410977FOG-001 in Locally Advanced or Metastatic Solid Tumors
- University of Colorado, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264Novel Couple-Based Mindfulness Intervention for Metastatic Colorectal Cancer
- University of Colorado Hospital, Aurora
RecruitingHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Aug 14, 2026 · NCT07759921A Study of MRG007 (ARR-217) in Patients With Advanced Solid Tumors
- University of Colorado, Aurora
- Sarah Cannon Research Institute, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT07066657A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201)
- GSK Investigational Site, Aurora
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT06885034A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
- Rocky Mountain Cancer Center, Denver
- Sarah Cannon Research Institute at HealthONE, Denver
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors
- Rocky Mountain Cancer Centers, Lone Tree
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT03526835A Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation
- Sarah Cannon Research Institue At Healthone, Denver
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06179160A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
- Rocky Mountain Cancer Centers, LLP, Aurora
- Rocky Mountain Cancer Centers, LLP, Boulder
- Rocky Mountain Cancer Centers, LLP, Colorado Springs
- and 8 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05253651A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
- University of Colorado Hospital - Anschutz Cancer Pavilion (ACP), Aurora
- University of Colorado Hospital, Aurora
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06131840From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.