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Cystic Fibrosis clinical trials in Boston, MA

17 studies for Cystic Fibrosis are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Phase 2 Study to Assess the Safety and Efficacy of ANG003

RecruitingPhase 2
  • Massachusetts General Hospital, Boston
  • Boston Children's Hospita, Boston
Ages 12 and older · All sexes · Updated Sep 28, 2026 · NCT07450547

Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

Recruiting
  • Boston Children's Hospital & Harvard University, Boston
Ages 3 to 18 · All sexes · Updated Aug 3, 2026 · NCT06654752

Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

RecruitingObservational study
  • Boston Children's Hospital, Boston
Up to age 10 · All sexes · Updated Jul 8, 2026 · NCT04509050

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

RecruitingPhase 4
  • Boston Children's Hospital, Brigham & Women's Hospital, Boston
Ages 6 and older · All sexes · Updated Jul 8, 2026 · NCT05548283

4D-710 in Adult Patients With Cystic Fibrosis

RecruitingPhase 2
  • Massachusetts General Hospital, Boston
  • Boston Children's Hospital, Boston
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT05248230

TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

RecruitingObservational study
  • Massachusetts General Hospital, Boston
18 Months – 11 Years · All sexes · Updated Jul 6, 2026 · NCT07048574

Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis

RecruitingPhase 2
  • Boston Children'S Hospital, Boston
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT06429176

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

RecruitingPhase 2
  • Boston Children's Hospital, Boston
Ages 18 and older · All sexes · Updated May 8, 2026 · NCT06747858

CF Wellness Program

Recruiting
  • Boston Children's Hospital, Boston
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT07071324

Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)

RecruitingObservational study
  • Massachusetts, Boston
Ages 12 and older · All sexes · Updated Feb 10, 2026 · NCT06837181

OnTrackCF: Engagement, Feasibility, and Acceptability Study

Recruiting
  • Boston Children's Hospital, Boston
Ages 18 and older · All sexes · Updated Dec 5, 2025 · NCT07031323

Health Outcomes of Parents With Cystic Fibrosis-Aim 2

RecruitingObservational study
  • Massachusetts General Hospital, Boston
  • Boston Children's Hospital/Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Nov 10, 2025 · NCT06296394

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

RecruitingObservational study
  • Massachusetts General Hospital, Boston
  • Boston Children's Hospital, Boston
Ages 6 and older · All sexes · Updated Nov 3, 2025 · NCT06683092

Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis

RecruitingObservational studyHealthy volunteers welcome
  • Boston Children's Hospital, Boston
Ages 13 to 20 · All sexes · Updated Oct 30, 2025 · NCT06216704

A Research Study to Advance the CF Therapeutics Pipeline for People Without Modulators

RecruitingObservational study
  • Massachusetts General Hospital, Boston
  • Boston Children's Hospital, Boston
Ages 12 and older · All sexes · Updated Oct 1, 2025 · NCT06504589

The Effects of a Low Glycemic Load Diet on Dysglycemia and Body Composition in Adults With Cystic Fibrosis-Related Diabetes

Recruiting
  • Boston Children's Hospital, Boston
Ages 18 to 70 · All sexes · Updated Aug 22, 2025 · NCT05723445

A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)

RecruitingPhase 1/2
  • Boston Children's Hospital, Brigham & Women's Hospital, Boston
Ages 18 to 65 · All sexes · Updated Nov 25, 2024 · NCT06526923

About Cystic Fibrosis

Cystic fibrosis (CF) is an inherited disease of the mucus and sweat glands. The symptoms and severity of CF can vary. Get the facts.

More about Cystic Fibrosis on MedlinePlus

Cystic Fibrosis trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.