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Dementia clinical trials in Chicago, IL

10 studies for Dementia are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

RecruitingPhase 3
  • Great Lakes Clinical Trials - Andersonville, Chicago
Ages 60 to 85 · All sexes · Updated Sep 17, 2026 · NCT06976203

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Northwestern University, Chicago
  • University of Illinois at Chicago, Chicago
  • Chicago VA Medical Center/Jesse Brown VA, Chicago
  • and 2 more
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

RecruitingPhase 3
  • Re:Cognition Health - Chicago, Chicago
Ages 60 to 85 · All sexes · Updated Aug 20, 2026 · NCT06976216

Medication Collaboration Feasibility Study

Recruiting
  • Northwestern University, Chicago
Ages 60 and older · All sexes · Updated Aug 14, 2026 · NCT07742189

Development of a Home Test for Measuring Blood P-tau217 in Alzheimer's Disease Using the Tasso Lancet Device

RecruitingObservational studyHealthy volunteers welcome
  • Insigth Hospital and Medical Center Chicago, Chicago
Ages 40 to 90 · All sexes · Updated Jul 14, 2026 · NCT07701161

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

RecruitingPhase 3
  • Great Lakes Clinical Trials - Andersonville, Chicago
Ages 55 and older · All sexes · Updated Jul 7, 2026 · NCT07602582

Communication Bridge 3 Study

RecruitingPhase 2
  • University of Chicago - American School Building, Chicago
Ages 18 to 100 · All sexes · Updated Jun 1, 2026 · NCT06191198

Development of a Personalized, Psychosocial Intervention for Menopausal Individuals With Elevated Dementia Risk

Recruiting
  • University of Chicago Medicine, Chicago
Ages 40 to 58 · Women · Updated Feb 5, 2026 · NCT06965686

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

RecruitingObservational studyHealthy volunteers welcome
  • Loyola University, Chicago
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT05677880

Alzheimer's National Registry for Treatment and Diagnostics(ALZ-NET)

RecruitingObservational study
  • Full List of Active Sites, Chicago
Ages 18 and older · All sexes · Updated Dec 14, 2023 · NCT06170268

About Dementia

People with dementia have serious problems with two or more brain functions, such as memory and language. Affects the ability to do normal activities.

More about Dementia on MedlinePlus

Dementia trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.