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Dementia clinical trials in Indianapolis, IN

8 studies for Dementia are looking for participants at sites in and around Indianapolis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

RecruitingPhase 3
  • Josephson Wallack Munshower Neurology, PC, Indianapolis
Ages 60 to 85 · All sexes · Updated Sep 17, 2026 · NCT06976203

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Indianapolis VA Medical Center, Indianapolis
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

Recruiting
  • Eskenazi Health, Indianapolis
Ages 65 and older · All sexes · Updated Aug 20, 2026 · NCT05643144

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

RecruitingPhase 2/3Healthy volunteers welcome
  • Indiana University School of Medicine, Indianapolis
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT06647498

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

RecruitingPhase 2/3Healthy volunteers welcome
  • Indiana University School of Medicine, Indianapolis
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT05552157

A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).

RecruitingPhase 3
  • Care Access - South Indianapolis, Indianapolis
  • Josephson Wallack Munshower Neurology, PC, Indianapolis
Ages 55 and older · All sexes · Updated Jul 7, 2026 · NCT07602582

Trial-Ready Cohort-Down Syndrome (TRC-DS)

RecruitingObservational study
  • Indiana University, Indianapolis
Ages 25 to 55 · All sexes · Updated May 18, 2026 · NCT04165109

Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD

Recruiting
  • Sidney & Lois Eskenazi Hospital, Indianapolis
Ages 65 and older · All sexes · Updated May 6, 2026 · NCT07499570

About Dementia

People with dementia have serious problems with two or more brain functions, such as memory and language. Affects the ability to do normal activities.

More about Dementia on MedlinePlus

Dementia trials in other cities

Other studies in Indianapolis

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.