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Diffuse Large B-Cell Lymphoma clinical trials in Durham, NC

14 studies for Diffuse Large B-Cell Lymphoma are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

RecruitingPhase 2
  • University of North Carolina Medical Center ( Site 0136), Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06890884

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

RecruitingPhase 2
  • Duke Blood Cancer Center, Durham
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT06500273

Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

RecruitingPhase 1/2
  • University of North Carolina at Chapel Hill/ University of North Carolina Medical Center, Chapel Hill · 10 mi away
Ages 13 to 90 · All sexes · Updated Aug 6, 2026 · NCT06533579

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

RecruitingObservational study
  • Duke University Medical Center - Division of Hematologic Malignancies, Durham
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06116110

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

RecruitingPhase 3
  • Duke Cancer Institute, Durham
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT07188558

DALY II USA/ MB-CART2019.1 for DLBCL

RecruitingPhase 2
  • Duke University Medical Center - Division of Hematologic Malignancies, Durham
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT04792489

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

RecruitingPhase 1
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT05131022

Registry of Older Patients With Cancer

RecruitingObservational study
  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill · 10 mi away
Ages 65 and older · All sexes · Updated Jun 29, 2026 · NCT01137825

Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.

RecruitingPhase 1
  • Duke Univerisity, Durham
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT04775745

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

RecruitingObservational study
  • Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill, Chapel Hill · 10 mi away
Ages 18 to 120 · All sexes · Updated Oct 27, 2025 · NCT01137643

A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

RecruitingPhase 1
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05780034

A Study of NX-1607 in Adults With Advanced Malignancies

RecruitingPhase 1
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 9, 2025 · NCT05107674

Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy

RecruitingPhase 2
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 26, 2024 · NCT06238648

Diffuse Large B-Cell Lymphoma trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.