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Diffuse Large B-Cell Lymphoma clinical trials in Boston, MA

16 studies for Diffuse Large B-Cell Lymphoma are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

RecruitingPhase 1/2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05006716

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

RecruitingPhase 2
  • Beth Israel Deaconess Medical Center ( Site 0161), Boston
  • Dana Farber Cancer Institute ( Site 0111), Boston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06890884

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07101328

A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07226843

Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)

RecruitingPhase 1/2
  • Dana-Farber Cancer Institute ( Site 1013), Boston
6 Months – 25 Years · All sexes · Updated Sep 17, 2026 · NCT06395103

Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL

RecruitingPhase 2
  • Boston Medical Center, Boston
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06806033

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

RecruitingPhase 2
  • Massachusetts General Hospital, Boston
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT06500273

A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04104776

Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

RecruitingObservational study
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06116110

The CARDIOPROTECT Trial

RecruitingPhase 2
  • Beth Israel Deaconess Medical Center, Boston
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT07654426

DALY II USA/ MB-CART2019.1 for DLBCL

RecruitingPhase 2
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT04792489

This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Apr 2, 2026 · NCT06451497

CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Mar 16, 2026 · NCT06026319

A Phase II Study of Glofitamab Plus Polatuzumab-R-CHP for Patients With High-risk Diffuse Large B-cell Lymphoma

RecruitingPhase 2
  • Beth Israel Deaconess Medical Center, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT05800366

Emapalumab Prevention of CAR-T Cell Associated Toxicities

RecruitingPhase 2
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Nov 14, 2025 · NCT06550141

Diffuse Large B-Cell Lymphoma trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.