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Diffuse Large B-Cell Lymphoma clinical trials in Cleveland, OH

11 studies for Diffuse Large B-Cell Lymphoma are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

RecruitingPhase 3
  • University Hospitals Cleveland Medical Center, Cleveland
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06091865

A Clinical Study of Zilovertamab Vedotin (MK-2140) Plus Rituximab Plus Cyclophosphamide, Doxorubicin, and Prednisone (R-CHP) Versus Polatuzumab Vedotin Plus R-CHP in People With Diffuse Large B-cell Lymphoma (DLBCL) (MK-2140-011/waveLINE-011)

RecruitingPhase 2
  • University Hospitals of Cleveland ( Site 0155), Cleveland
  • Fairview Hospital-Moll Cancer Center ( Site 0198), Cleveland
  • Cleveland Clinic Main ( Site 0101), Cleveland
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06890884

A Study of LY4152199 in Participants With Previously Treated B-cell Malignancies (BAF_FRontier-1 )

RecruitingPhase 1
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07101328

Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

RecruitingPhase 1
  • Case Comprehensive Cancer Center, University Hospitals Seidman Cancer Center, Cleveland
  • Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute, Cleveland
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07225439

Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL

RecruitingPhase 2
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Aug 31, 2026 · NCT06500273

Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

RecruitingPhase 1/2
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT05826535

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

RecruitingPhase 3
  • Cleveland Clinical Taussig Cancer Center, Cleveland
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT07188558

Testing the Combination of Anti-cancer Drugs Mosunetuzumab, Polatuzumab Vedotin, and Lenalidomide for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

RecruitingPhase 1
  • Case Western Reserve University, Cleveland
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT06015880

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

RecruitingPhase 1
  • Cleveland Clinic, Cleveland
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT05131022

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

RecruitingPhase 2
  • Case Western Reserve University, Cleveland
Ages 18 and older · All sexes · Updated Feb 2, 2026 · NCT05633615

A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

RecruitingPhase 1
  • University Hospitals Cleveland Medical Center, Cleveland
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05780034

Diffuse Large B-Cell Lymphoma trials in other cities

Other studies in Cleveland

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.