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Heart Failure clinical trials in Florida
51 studies for Heart Failure are looking for participants at sites in Florida.
Cities in Florida
- Jacksonville20 studies
- Tampa18 studies
- Orlando16 studies
- Gainesville13 studies
- Miami13 studies
- Hialeah12 studies
- Hollywood8 studies
- St. Petersburg7 studies
- Davie7 studies
- Pensacola6 studies
- Clearwater6 studies
- Kendall6 studies
- Boca Raton6 studies
- West Palm Beach6 studies
- Palm Coast6 studies
- Ocala5 studies
- Fort Lauderdale5 studies
- Spring Hill5 studies
- Naples4 studies
- Sarasota4 studies
- Lakeland3 studies
- Brandon3 studies
- Miramar3 studies
- Pembroke Pines3 studies
- Miami Beach3 studies
- Deltona3 studies
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
- Johns Hopkins All Children's Hospital ( Site 0029), St. Petersburg
RecruitingPhase 2/3
29 Days – 17 Years · All sexes · Updated Nov 13, 2026 · NCT05714085A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction
- Synergy Healthcare, Bradenton
- Nature Coast Clinical Research LLC, Inverness
- Jacksonville Center for Clinical, Jacksonville
- and 2 more
RecruitingPhase 1
Ages 18 to 100 · All sexes · Updated Nov 12, 2026 · NCT07465653A Study to Evaluate the Safety and Efficacy of AC01 Compared to Placebo in Participants With Chronic Heart Failure
- Nature Coast Clinical Research, Crystal River
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Nov 12, 2026 · NCT07584967A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- Flourish Research, Boca Raton
- Bay Area Cardiology, Brandon
- Clearwater Cardiovascular and Interventional Consultants, Clearwater
- and 19 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06424288A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
- Cardiology Associates Research Co., Daytona Beach
- Suncoast Research Associates, LLC, Doral
- Malcom Randall VA Medical Center, Gainesville
- and 14 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06935370INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
- NCH Rooney Heart Institute, Naples
- Tampa General Hospital, Tampa
Recruiting
Ages 18 to 80 · All sexes · Updated Nov 12, 2026 · NCT06965504Left vs Left Randomized Clinical Trial
- Heart Rhythm Solutions, Davie
- University of Florida Jacksonville, Jacksonville
- Mount Sinai Medical Center of Florida, Inc., Miami Beach
- and 3 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT05650658A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
- Cleveland Clinic Florida - Weston, Weston
Recruiting
Ages 18 to 85 · All sexes · Updated Nov 10, 2026 · NCT07214376Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure
- BayCare Health System, Clearwater
- First Coast Cardiovascular Institute, Jacksonville
- AdventHealth Orlando, Orlando
- and 3 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07232030Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Shands at the University of Florida, Gainesville
- Cleveland Clinic Florida, Weston
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- Clearwater
- Hollywood
- Jacksonville
- and 4 more
RecruitingObservational study
All ages · All sexes · Updated Nov 4, 2026 · NCT00271180Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
- CHF Heart Clinical (Subject Visits & IP Shipments), Clearwater
- Holy Cross Medical Group - Cardiology Associates, Fort Lauderdale
- South Florida Research Solutions, LLC, Hollywood
- and 6 more
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Nov 4, 2026 · NCT06736574Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
- Sarasota Memorial Hospital, Sarasota
- AdventHealth Tampa, Tampa
Recruiting
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07069738ELEVATE-HFpEF Clinical Study
- Cardiovascular Institute of Northwest Florida, Panama City
Recruiting
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
- Orlando Heart and Vascular Institute, Altamonte Springs
- D and H Tamarac Research Center, Aventura
- Excel Medical Clinical Trials, Boca Raton
- and 18 more
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Oct 29, 2026 · NCT07037459A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
- UF Health Shands Hospital - Pediatric Cardiology, Gainesville
- Joe Dimaggio Children's Hospital - Cardiology, Hollywood
RecruitingPhase 3
Up to age 18 · All sexes · Updated Oct 27, 2026 · NCT07192952CCM OPEN HF Registry
- AdventHealth Orlando, Orlando
- AdventHealth Tampa, Tampa
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT07112924Cardiogenic Shock Working Group Registry
- Cleveland Clinic Florida, Weston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Oct 27, 2026 · NCT04682483A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
- Jacksonville Center for Clinical Research, Jacksonville
- Infinite Clinical Research, Miami
- Flourish Research Acquisition, LLC dba Flourish Research - North Miami, Miami
- and 3 more
RecruitingPhase 2
Ages 18 to 79 · All sexes · Updated Oct 23, 2026 · NCT06991257Assessment of CCM in HF With Higher Ejection Fraction
- Nouvelle Clinical Research LLC, Cutler Bay
- Baptist Health South Florida, Miami
- AdventHealth Orlando, Orlando
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT05064709Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Boca Raton
- Research Site, Crystal River
- Research Site, Fort Myers
- and 11 more
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Oct 21, 2026 · NCT06677060The WiSE®-UP Study (The WiSE System Utilization & Performance Study)
- Naples Community Hospital, Naples
RecruitingObservational study
Ages 22 and older · All sexes · Updated Oct 16, 2026 · NCT07098858NORM-HF Pivotal Study
- University of Florida Health - Jacksonville, Jacksonville
- Tampa General Hospital, Tampa
- Baycare Health System, Tampa
Recruiting
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07574593A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
- UF Health Shands Hospital - Pediatric Cardiology, Gainesville
- Joe Dimaggio Children's Hospital - Cardiology, Hollywood
RecruitingPhase 3
6 Months – 17 Years · All sexes · Updated Oct 15, 2026 · NCT07188805A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
- Local Institution - 24, Gainesville
RecruitingPhase 2
Ages 30 to 84 · All sexes · Updated Oct 13, 2026 · NCT07795814Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Boca Raton
- Research Site, Bradenton
- Research Site, Delray Beach
- and 11 more
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Oct 13, 2026 · NCT06307652CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
- North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville
Recruiting
Ages 60 and older · All sexes · Updated Oct 7, 2026 · NCT05996328Alleviant ALLAY-HFrEF Study
- Delray Medical Center, Delray Beach
- Ascension Sacred Heart, Pensacola
- Tampa General Hospital, Tampa
Recruiting
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT06812533A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
- Inpatient Research Clinic LLC, Miami Lakes
- AdventHealth Orlando, Orlando
- Guardian Research Org LLC, Winter Park
RecruitingPhase 2
Ages 40 to 84 · All sexes · Updated Oct 5, 2026 · NCT06979362A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
- Research Site, Hallandale
- Research Site, Jacksonville
- Research Site, Lakeland
- and 8 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
- Bradenton, FL Investigative Site CON-10125, Bradenton
- Fort Lauderdale, FL Investigative Site CON-10114, Fort Lauderdale
- CON-10078, Hialeah, FL, Hialeah
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Bradenton, FL Investigative Site 10125, Bradenton
- Brooksville, FL Investigative Site 10077, Brooksville
- Fort Lauderdale, FL Investigative Site 10114, Fort Lauderdale
- and 7 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
- Las Mercedes Medical Research, Hialeah
- New Generation of Medical Research, Hialeah
- Cleveland Clinic Florida, Weston
RecruitingPhase 2
Ages 40 to 85 · All sexes · Updated Aug 27, 2026 · NCT06793371Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
- Research Site, Jacksonville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07690436Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
- Broward Health, Fort Lauderdale
- University of South Florida, Tampa
- BayCare Medical/St. Joseph's Hospital, Tampa
- and 2 more
Recruiting
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure
- Baptist Health South Florida, Miami
- Orlando Health, Orlando
Recruiting
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05650541A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
- BayCare Health System, Clearwater
- Broward Research Ctr., Coral Gables
- Nature Coast Clinical Research, Crystal River
- and 21 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001Alleviant ALLAY-HF Study
- The Cardiac and Vascular Institute (TCAVI), Gainesville
- HCA Florida Memorial Hospital, Jacksonville
- NCH Research Institute, Naples
- and 2 more
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer
- University of Florida, Gainesville
- Mayo Clinic in Florida, Jacksonville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT05507879Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1
Ages 18 to 80 · All sexes · Updated Jul 31, 2026 · NCT06770023From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.