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Heart Failure clinical trials in Florida
50 studies for Heart Failure are looking for participants at sites in Florida.
Cities in Florida
- Jacksonville21 studies
- Tampa18 studies
- Orlando16 studies
- Miami14 studies
- Gainesville13 studies
- Hialeah12 studies
- St. Petersburg8 studies
- Hollywood8 studies
- Palm Coast7 studies
- West Palm Beach7 studies
- Kendall6 studies
- Fort Lauderdale6 studies
- Clearwater6 studies
- Pensacola6 studies
- Davie6 studies
- Spring Hill5 studies
- Ocala5 studies
- Boca Raton5 studies
- Sarasota4 studies
- Lakeland3 studies
- Miramar3 studies
- Deltona3 studies
- Miami Beach3 studies
- Brandon3 studies
- Naples3 studies
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
- Research Site, Hallandale
- Research Site, Jacksonville
- Research Site, Lakeland
- and 8 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
- CHF Heart Clinical (Subject Visits & IP Shipments), Clearwater
- Holy Cross Medical Group - Cardiology Associates, Fort Lauderdale
- South Florida Research Solutions, LLC, Hollywood
- and 5 more
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure
- BayCare Health System, Clearwater
- First Coast Cardiovascular Institute, Jacksonville
- Tallahassee Research Institute, Tallahassee
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07232030A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
- Bay Area Cardiology, Brandon
- Cardiology Associates Research Co., Daytona Beach
- Suncoast Research Associates, LLC, Doral
- and 15 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06935370A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- Flourish Research, Boca Raton
- Bay Area Cardiology, Brandon
- Clearwater Cardiovascular and Interventional Consultants, Clearwater
- and 19 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06424288Alleviant ALLAY-HFrEF Study
- Delray Medical Center, Delray Beach
- Ascension Sacred Heart, Pensacola
- Tampa General Hospital, Tampa
Recruiting
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06812533Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
- Orlando Heart and Vascular Institute, Altamonte Springs
- D and H Tamarac Research Center, Aventura
- Excel Medical Clinical Trials, Boca Raton
- and 18 more
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Crystal River
- Research Site, Fort Myers
- Research Site, Jacksonville
- and 8 more
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Boca Raton
- Research Site, Bradenton
- Research Site, Delray Beach
- and 11 more
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Sep 11, 2026 · NCT06307652A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Bradenton, FL Investigative Site 10125, Bradenton
- Brooksville, FL Investigative Site 10077, Brooksville
- Fort Lauderdale, FL Investigative Site 10114, Fort Lauderdale
- and 7 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
- Bradenton, FL Investigative Site CON-10125, Bradenton
- Fort Lauderdale, FL Investigative Site CON-10114, Fort Lauderdale
- CON-10078, Hialeah, FL, Hialeah
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746The WiSE®-UP Study (The WiSE System Utilization & Performance Study)
- Naples Community Hospital, Naples
RecruitingObservational study
Ages 22 and older · All sexes · Updated Sep 10, 2026 · NCT07098858A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction
- Synergy Healthcare, Bradenton
- Nature Coast Clinical Research LLC, Inverness
- Jacksonville Center for Clinical, Jacksonville
- and 2 more
RecruitingPhase 1
Ages 18 to 100 · All sexes · Updated Sep 10, 2026 · NCT07465653Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- UF Health Shands Hospital, Gainsville
- Advent Health, Orlando
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
- Sarasota Memorial Hospital, Sarasota
- AdventHealth Tampa, Tampa
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
- Johns Hopkins All Children's Hospital ( Site 0029), St. Petersburg
RecruitingPhase 2/3
29 Days – 17 Years · All sexes · Updated Aug 28, 2026 · NCT05714085AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
- Las Mercedes Medical Research, Hialeah
- New Generation of Medical Research, Hialeah
- Cleveland Clinic Florida, Weston
RecruitingPhase 2
Ages 40 to 85 · All sexes · Updated Aug 27, 2026 · NCT06793371Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
- Research Site, Jacksonville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07690436NORM-HF Pivotal Study
- University of Florida Health - Jacksonville, Jacksonville
- Baycare Health System, Tampa
Recruiting
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07574593Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
- Broward Health, Fort Lauderdale
- University of South Florida, Tampa
- BayCare Medical/St. Joseph's Hospital, Tampa
- and 2 more
Recruiting
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- Clearwater
- Hollywood
- Jacksonville
- and 4 more
RecruitingObservational study
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure
- Baptist Health South Florida, Miami
- Orlando Health, Orlando
Recruiting
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05650541A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
- BayCare Health System, Clearwater
- Broward Research Ctr., Coral Gables
- Nature Coast Clinical Research, Crystal River
- and 21 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001Alleviant ALLAY-HF Study
- The Cardiac and Vascular Institute (TCAVI), Gainesville
- HCA Florida Memorial Hospital, Jacksonville
- NCH Research Institute, Naples
- and 2 more
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
- North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville
Recruiting
Ages 60 and older · All sexes · Updated Aug 14, 2026 · NCT05996328Assessment of CCM in HF With Higher Ejection Fraction
- HCA Florida JFK Hospital, Atlantis
- Nouvelle Clinical Research LLC, Cutler Bay
- Broward Health, Fort Lauderdale
- and 4 more
Recruiting
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
- Inpatient Research Clinic LLC, Miami Lakes
- AdventHealth Orlando, Orlando
- Guardian Research Org LLC, Winter Park
RecruitingPhase 2
Ages 40 to 84 · All sexes · Updated Aug 5, 2026 · NCT06979362TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer
- University of Florida, Gainesville
- Mayo Clinic in Florida, Jacksonville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT05507879ELEVATE-HFpEF Clinical Study
- Cardiovascular Institute of Northwest Florida, Panama City
Recruiting
Ages 40 and older · All sexes · Updated Aug 3, 2026 · NCT06678841Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension
- Mayo Clinic in Florida, Jacksonville
RecruitingPhase 1
Ages 18 to 80 · All sexes · Updated Jul 31, 2026 · NCT06770023A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
- Bradenton, FL Investigative Site FIN-10125, Bradenton
- FIN-10104, Hialeah, FL, Hialeah
- FIN-10028, Jacksonville, FL, Jacksonville
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06033950PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
- Baptist Health South Florida, Miami
- Ascension Sacred Heart, Pensacola
Recruiting
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
- UF Health Shands Hospital - Pediatric Cardiology, Gainesville
- Joe Dimaggio Children's Hospital - Cardiology, Hollywood
RecruitingPhase 3
Up to age 18 · All sexes · Updated Jun 29, 2026 · NCT07192952A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
- UF Health Shands Hospital - Pediatric Cardiology, Gainesville
- Joe Dimaggio Children's Hospital - Cardiology, Hollywood
RecruitingPhase 3
6 Months – 17 Years · All sexes · Updated Jun 15, 2026 · NCT07188805Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Shands at the University of Florida, Gainesville
- Cleveland Clinic Florida, Weston
Recruiting
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart Failure
- University of Florida, Gainesville
RecruitingPhase 4
Ages 18 to 80 · All sexes · Updated Jun 8, 2026 · NCT06979726A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
- Jacksonville Center for Clinical Research, Jacksonville
- Infinite Clinical Research, Miami
- Flourish Research Acquisition, LLC dba Flourish Research - North Miami, Miami
- and 2 more
RecruitingPhase 2
Ages 18 to 79 · All sexes · Updated May 27, 2026 · NCT06991257Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
- Excel Medical Clinical Trials LLC, Boca Raton
RecruitingPhase 3
Ages 6 to 11 · All sexes · Updated May 15, 2026 · NCT06597019CCM OPEN HF Registry
- AdventHealth Orlando, Orlando
- AdventHealth Tampa, Tampa
RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT07112924The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
- Advent Health Hospital, Orlando
- Palm Beach Gardens Medical, Palm Beach
- Tampa General Hospital, Tampa
Recruiting
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.