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Heart Failure clinical trials in Jacksonville, FL

21 studies for Heart Failure are looking for participants at sites in and around Jacksonville (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

RecruitingPhase 3
  • Research Site, Jacksonville
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

RecruitingPhase 3
  • UF Health Jacksonville, Jacksonville
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574

Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure

Recruiting
  • First Coast Cardiovascular Institute, Jacksonville
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07232030

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

RecruitingPhase 3
  • University of Florida Health Jacksonville, Jacksonville
  • East Coast Institute for Research, LLC - Jacksonville, Jacksonville
  • First Coast Cardiovascular Institute, Jacksonville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06424288

A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart

RecruitingPhase 3
  • University of Florida, Jacksonville
  • East Coast Institute For Research, LLC, Jacksonville
  • Jacksonville Center for Clinical Research, Jacksonville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06935370

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

RecruitingPhase 3
  • East Coast Institute for Research, Jacksonville
  • First Coast Cardiovascular Institute PA, Jacksonville
  • Jacksonville Center for Clinical Research, Jacksonville
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

RecruitingPhase 3
  • Research Site, Jacksonville
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

RecruitingPhase 3
  • Research Site, Jacksonville
Ages 18 to 130 · All sexes · Updated Sep 11, 2026 · NCT06307652

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

RecruitingPhase 3
  • Jacksonville, FL Investigative Site 10028, Jacksonville
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197

A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction

RecruitingPhase 1
  • Jacksonville Center for Clinical, Jacksonville
Ages 18 to 100 · All sexes · Updated Sep 10, 2026 · NCT07465653

Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM

RecruitingObservational study
  • Research Site, Jacksonville
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07690436

NORM-HF Pivotal Study

Recruiting
  • University of Florida Health - Jacksonville, Jacksonville
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07574593

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

RecruitingObservational study
  • Jacksonville, Jacksonville
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • Jacksonville Ctr for Clin Res, Jacksonville
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

Alleviant ALLAY-HF Study

Recruiting
  • HCA Florida Memorial Hospital, Jacksonville
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303

TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer

RecruitingObservational study
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT05507879

Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension

RecruitingPhase 1
  • Mayo Clinic in Florida, Jacksonville
Ages 18 to 80 · All sexes · Updated Jul 31, 2026 · NCT06770023

A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)

RecruitingPhase 2
  • Jacksonville Center for Clinical Research, Jacksonville
Ages 18 to 79 · All sexes · Updated May 27, 2026 · NCT06991257

Left vs Left Randomized Clinical Trial

Recruiting
  • University of Florida Jacksonville, Jacksonville
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05650658

AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

RecruitingObservational study
  • Jacksonville Center for Clinical Research, Jacksonville
Ages 22 and older · All sexes · Updated Mar 26, 2025 · NCT06378632

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Jacksonville

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.