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Heart Failure clinical trials in Ohio
53 studies for Heart Failure are looking for participants at sites in Ohio.
Cities in Ohio
- Cleveland31 studies
- Cincinnati22 studies
- Columbus14 studies
- Toledo8 studies
- Dayton8 studies
- Akron4 studies
- Marion3 studies
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
- Cincinnati Children's Hospital Medical Center ( Site 0034), Cincinnati
- Cleveland Clinic-Cleveland Clinic Chidren's ( Site 0022), Cleveland
RecruitingPhase 2/3
29 Days – 17 Years · All sexes · Updated Nov 13, 2026 · NCT05714085A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- K and R Research LLC, Marion
- Mercy Health St. Vincent Medical Center, Toledo
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06424288A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
- VA Northeast Ohio Healthcare System, Cleveland
- K and R Research LLC, Marion
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06935370Left vs Left Randomized Clinical Trial
- The Christ Hospital, Cincinnati
- The MetroHealth System, Cleveland
- Cleveland Clinic, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT05650658A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease
- Cleveland Clinic, Cleveland
Recruiting
Ages 18 to 85 · All sexes · Updated Nov 10, 2026 · NCT07214376Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure
- The Christ Hospital, Cincinnati
Recruiting
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07232030Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Christ Hospital, Cincinnati
- The Cleveland Clinic Foundation, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- Cincinnati
- Cleveland
- Columbus
- and 1 more
RecruitingObservational study
All ages · All sexes · Updated Nov 4, 2026 · NCT00271180Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
- The Lindner Research Center at the Christ Hospital, Cincinnati
- University Hospitals Cleveland Medical Center, Cleveland
- Cleveland Clinic, Cleveland
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Nov 4, 2026 · NCT06736574Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
- OhioHealth Research and Innovation Institute-Riverside Methodist Hospital, Columbus
- Mount Carmel Health System, Columbus
Recruiting
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07069738ELEVATE-HFpEF Clinical Study
- The Ohio State University Wexner Medical Center, Columbus
- Mount Carmel East, Columbus
Recruiting
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
- Cincinnati Children's Hospital Medical Center | Division of Nephrology and Hypertension, Cincinnati
- Cleveland Clinic Children's, Cleveland
- Nationwide Children's Hospital - Cardiology, Columbus
RecruitingPhase 3
Up to age 18 · All sexes · Updated Oct 27, 2026 · NCT07192952A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
- NexGen Research, Lima
RecruitingPhase 2
Ages 18 to 79 · All sexes · Updated Oct 23, 2026 · NCT06991257Assessment of CCM in HF With Higher Ejection Fraction
- Cleveland Clinic Foundation, Cleveland
- Ohio State University Wexner Medical Center, Columbus
- OhioHealth Research Institute, Columbus
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT05064709Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues
- The Ohio State University Wexner Medical Center, Columbus
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT01757730Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Beavercreek
- Research Site, Canton
- Research Site, Cincinnati
- and 6 more
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Oct 21, 2026 · NCT06677060Fluid Guided Heart Failure Treatment at the Cleveland Clinic
- The Cleveland Clinic, Cleveland
Recruiting
Ages 21 and older · All sexes · Updated Oct 20, 2026 · NCT07205120Ketogenic Diet vs Mixed Diet in Patients With Heart Failure
- The Ross Heart Hospital, Columbus
Recruiting
Ages 18 to 80 · All sexes · Updated Oct 19, 2026 · NCT06081543The WiSE®-UP Study (The WiSE System Utilization & Performance Study)
- Cleveland Clinic Foundation, Cleveland
RecruitingObservational study
Ages 22 and older · All sexes · Updated Oct 16, 2026 · NCT07098858NORM-HF Pivotal Study
- Christ Hospital Lindner, Cincinnati
- Ohio State University Hospital, Colombus
- ProMedica Toledo Hospital, Toledo
Recruiting
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07574593A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
- Cincinnati Children's Hospital Medical Center | Division of Nephrology and Hypertension, Cincinnati
- Cleveland Clinic Children's, Cleveland
- Nationwide Children's Hospital - Cardiology, Columbus
RecruitingPhase 3
6 Months – 17 Years · All sexes · Updated Oct 15, 2026 · NCT07188805A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
- Local Institution - 15, Cincinnati
RecruitingPhase 2
Ages 30 to 84 · All sexes · Updated Oct 13, 2026 · NCT07795814Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Cincinnati
- Research Site, Springfield
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Oct 13, 2026 · NCT06307652Home-Based Exercise Program Using Mobile Technology After Left Ventricular Assist Device Implantation
- Cleveland Clinic Foundation, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Oct 7, 2026 · NCT06291922CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
- Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
Recruiting
Ages 60 and older · All sexes · Updated Oct 7, 2026 · NCT05996328Alleviant ALLAY-HFrEF Study
- Cleveland Clinic, Cleveland
- ProMedica Toledo Hospital, Toledo
Recruiting
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT06812533Early Feasibility Study - Edwards APTURE Transcatheter Shunt System
- The Ohio State University Medical Center, Columbus
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT03523416A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
- Research Site, Columbus
- Research Site, Dayton
- Research Site, Maumee
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117BiVACOR® Total Artificial Heart Early Feasibility Study
- The Christ Hospital, Cincinnati
Recruiting
Ages 18 to 70 · All sexes · Updated Sep 28, 2026 · NCT06174103A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
- CON-10119, Centerville, OH, Centerville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Akron, OH Investigative Site 10081, Akron
- Centerville, OH Investigative Site 10119, Centerville
- Cincinnati, OH Investigative Site 10088, Cincinnati
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation
- Cleveland Clinic, Cleveland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT07436299AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
- The Lindner Center for Research & Education at The Christ Hospital, Cincinnati
RecruitingPhase 2
Ages 40 to 85 · All sexes · Updated Aug 27, 2026 · NCT06793371Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
- The Ohio State University, Columbus
Recruiting
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
- Cincinnati Childrens Hospital Medical Center, Cincinnati
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
- Christ Hospital Health Network, Cincinnati
- University Hospitals Cleveland Medical Center, Cleveland
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
- Aultman Hospital, Canton
- Lindner Center,Christ Hospital, Cincinnati
- Louis Stokes Clvlnd VA Med Ctr, Cleveland
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001Alleviant ALLAY-HF Study
- Cleveland Clinic, Cleveland
- ProMedica Toledo Hospital, Toledo
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303Longitudinal Validation of CIRC Technologies
- Cleveland Clinic, Cleveland
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07081711A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
- FIN-10081, Akron, OH, Akron
- FIN-10119, Centerville, OH, Centerville
- FIN- 10112, Cincinnati, OH, Cincinnati
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06033950From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.