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Heart Failure clinical trials in Cincinnati, OH

24 studies for Heart Failure are looking for participants at sites in and around Cincinnati (within about 30 miles). Open a study to see who can join and how to contact the study team.

BiVACOR® Total Artificial Heart Early Feasibility Study

Recruiting
  • The Christ Hospital, Cincinnati
Ages 18 to 70 · All sexes · Updated Sep 28, 2026 · NCT06174103

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

RecruitingPhase 3
  • The Lindner Research Center at the Christ Hospital, Cincinnati
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574

Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure

Recruiting
  • The Christ Hospital, Cincinnati
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07232030

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

RecruitingPhase 3
  • Research Site, Cincinnati
  • Research Site, Cincinnati
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060

Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function

RecruitingPhase 3
  • Research Site, Cincinnati
  • Research Site, Cincinnati
Ages 18 to 130 · All sexes · Updated Sep 11, 2026 · NCT06307652

A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients

RecruitingPhase 3
  • Cincinnati, OH Investigative Site 10088, Cincinnati
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197

Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure

Recruiting
  • The Christ Hospital - Cincinnati, Cincinnati
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031

A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)

RecruitingPhase 2
  • Local Institution - 129, Cincinnati
Ages 30 to 84 · All sexes · Updated Aug 31, 2026 · NCT07795814

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

RecruitingPhase 2/3
  • Cincinnati Children's Hospital Medical Center ( Site 0034), Cincinnati
29 Days – 17 Years · All sexes · Updated Aug 28, 2026 · NCT05714085

AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF

RecruitingPhase 2
  • The Lindner Center for Research & Education at The Christ Hospital, Cincinnati
Ages 40 to 85 · All sexes · Updated Aug 27, 2026 · NCT06793371

NORM-HF Pivotal Study

Recruiting
  • Christ Hospital Lindner, Cincinnati
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07574593

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

RecruitingObservational studyHealthy volunteers welcome
  • Cincinnati Childrens Hospital Medical Center, Cincinnati
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

RecruitingObservational study
  • Cincinnati, Cincinnati
  • Edgewood, Edgewood · 8 mi away
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • Lindner Center,Christ Hospital, Cincinnati
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

Alleviant ALLAY-HF Study

Recruiting
  • St. Elizabeth Healthcare, Edgewood · 8 mi away
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

Recruiting
  • The Christ Hospital- Cincinnati, Cincinnati
  • University of Cincinnati, Cincinnati
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05934487

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

RecruitingPhase 3
  • Cincinnati Children's Hospital Medical Center | Division of Nephrology and Hypertension, Cincinnati
Up to age 18 · All sexes · Updated Jun 29, 2026 · NCT07192952

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

RecruitingPhase 3
  • Cincinnati Children's Hospital Medical Center | Division of Nephrology and Hypertension, Cincinnati
6 Months – 17 Years · All sexes · Updated Jun 15, 2026 · NCT07188805

Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure

Recruiting
  • Christ Hospital, Cincinnati
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06526195

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • Lindner Research Center at the Christ Hospital, Cincinnati
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Left vs Left Randomized Clinical Trial

Recruiting
  • The Christ Hospital, Cincinnati
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05650658

AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

RecruitingObservational study
  • The Lindner Research Center at The Christ Hospital, Cincinnati
  • St. Elizabeth Healthcare, Edgewood · 8 mi away
Ages 22 and older · All sexes · Updated Mar 26, 2025 · NCT06378632

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Cincinnati

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.