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Heart Failure clinical trials in Columbus, OH

15 studies for Heart Failure are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

RecruitingPhase 3
  • Research Site, Columbus
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

RecruitingPhase 3
  • Research Site, Columbus
  • Research Site, Columbus
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

Recruiting
  • OhioHealth Research and Innovation Institute-Riverside Methodist Hospital, Columbus
  • Mount Carmel Health System, Columbus
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Recruiting
  • The Ohio State University, Columbus
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100

Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

RecruitingObservational study
  • Columbus, Columbus
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180

LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2

RecruitingPhase 3
  • Tenax Investigational Site, Columbus
Ages 18 to 85 · All sexes · Updated Aug 19, 2026 · NCT07288398

Assessment of CCM in HF With Higher Ejection Fraction

Recruiting
  • Ohio State University Wexner Medical Center, Columbus
  • OhioHealth Research Institute, Columbus
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709

ELEVATE-HFpEF Clinical Study

Recruiting
  • The Ohio State University Wexner Medical Center, Columbus
  • Mount Carmel East, Columbus
Ages 40 and older · All sexes · Updated Aug 3, 2026 · NCT06678841

Ketogenic Diet vs Mixed Diet in Patients With Heart Failure

Recruiting
  • The Ross Heart Hospital, Columbus
Ages 18 to 80 · All sexes · Updated Jul 23, 2026 · NCT06081543

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

RecruitingPhase 3
  • Nationwide Children's Hospital - Cardiology, Columbus
Up to age 18 · All sexes · Updated Jun 29, 2026 · NCT07192952

Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)

RecruitingObservational study
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06641362

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • The Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues

RecruitingObservational studyHealthy volunteers welcome
  • The Ohio State University Wexner Medical Center, Columbus
Ages 18 and older · All sexes · Updated Apr 6, 2025 · NCT01757730

AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM

RecruitingObservational study
  • The Ohio State University, Columbus
Ages 22 and older · All sexes · Updated Mar 26, 2025 · NCT06378632

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.