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Heart Failure clinical trials in Columbus, OH

14 studies for Heart Failure are looking for participants at sites in and around Columbus (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products

RecruitingObservational study
  • Columbus, Columbus
All ages · All sexes · Updated Nov 4, 2026 · NCT00271180

Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

Recruiting
  • OhioHealth Research and Innovation Institute-Riverside Methodist Hospital, Columbus
  • Mount Carmel Health System, Columbus
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07069738

ELEVATE-HFpEF Clinical Study

Recruiting
  • The Ohio State University Wexner Medical Center, Columbus
  • Mount Carmel East, Columbus
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

RecruitingPhase 3
  • Nationwide Children's Hospital - Cardiology, Columbus
Up to age 18 · All sexes · Updated Oct 27, 2026 · NCT07192952

Assessment of CCM in HF With Higher Ejection Fraction

Recruiting
  • Ohio State University Wexner Medical Center, Columbus
  • OhioHealth Research Institute, Columbus
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT05064709

Magnetic Resonance Elastography as a Method to Estimate Stiffness of Soft Tissues

RecruitingObservational studyHealthy volunteers welcome
  • The Ohio State University Wexner Medical Center, Columbus
Ages 18 and older · All sexes · Updated Oct 21, 2026 · NCT01757730

Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin

RecruitingPhase 3
  • Research Site, Columbus
  • Research Site, Columbus
Ages 40 and older · All sexes · Updated Oct 21, 2026 · NCT06677060

Ketogenic Diet vs Mixed Diet in Patients With Heart Failure

Recruiting
  • The Ross Heart Hospital, Columbus
Ages 18 to 80 · All sexes · Updated Oct 19, 2026 · NCT06081543

Early Feasibility Study - Edwards APTURE Transcatheter Shunt System

Recruiting
  • The Ohio State University Medical Center, Columbus
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT03523416

A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF

RecruitingPhase 3
  • Research Site, Columbus
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117

Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure

Recruiting
  • The Ohio State University, Columbus
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100

Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)

RecruitingObservational study
  • Ohio State University, Columbus
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT06641362

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

Recruiting
  • The Ohio State University, Columbus
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT03142152

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Columbus

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.