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Type 2 Diabetes clinical trials in San Antonio, TX

37 studies for Type 2 Diabetes are looking for participants at sites in and around San Antonio (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Evaluation of MiniMed Next Generation Extended Wear Sensors and Algorithm in Patients With Type 1 and Type 2 Diabetes

Recruiting
  • Diabetes and Glandular Disease Clinic, San Antonio
Ages 2 to 80 · All sexes · Updated Nov 13, 2026 · NCT07864168

A Study to Test Whether Survodutide Helps People With Type 2 Diabetes Control Their Blood Sugar

RecruitingPhase 3
  • Pinnacle Clinical Research - San Antonio, San Antonio
  • Pinnacle Clinical Research, LLC, San Antonio
  • Consano Clinical Research, Shavano Park · 12 mi away
Ages 18 and older · All sexes · Updated Nov 13, 2026 · NCT07754461

EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease

RecruitingPhase 3
  • IMA Clinical Research San Antonio, San Antonio
  • Pinnacle Clinical Research, LLC, San Antonio
  • University of Texas Health Science Center at San Antonio, San Antonio
  • and 3 more
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT07064473

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

RecruitingPhase 3
  • Pinnacle Clinical Research - San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07351058

A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes

RecruitingPhase 3
  • Consano Clinical Research, LLC, Shavano Park · 12 mi away
Ages 10 to 17 · All sexes · Updated Nov 5, 2026 · NCT07668336

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

RecruitingPhase 3
  • VIP Trials, San Antonio
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07595549

A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 Diabetes

RecruitingPhase 3
  • IMA Clinical Research San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07881458

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

RecruitingPhase 3
  • IMA Clinical Research San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT07282600

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

RecruitingPhase 2
  • Consano Clinical Research, LLC, Shavano Park · 12 mi away
Ages 18 to 75 · All sexes · Updated Nov 4, 2026 · NCT06897475

A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

RecruitingPhase 3
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Oct 30, 2026 · NCT07662109

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

RecruitingPhase 3
  • Research Site, San Antonio
  • Research Site, San Antonio
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Oct 28, 2026 · NCT07784270

Study to Assess the Effects of ALN-ANG3 in Adult Participants With Diabetic Kidney Disease

RecruitingPhase 2
  • Clinical Advancement Center, San Antonio
  • University of Texas Health - San Antonio, San Antonio
Ages 18 to 80 · All sexes · Updated Oct 27, 2026 · NCT07271186

A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

RecruitingPhase 3
  • Research Site, San Antonio
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Oct 22, 2026 · NCT07662213

Phase 2 Trial of Icovamenib in Participants With Type 2 Diabetes Mellitus Who Are Not Achieving Glycemic Targets While Using GLP-1-Based Therapy

RecruitingPhase 2
  • Diabetes & Glandular Disease Clinic, P.A., San Antonio
Ages 18 to 75 · All sexes · Updated Oct 20, 2026 · NCT07502508

A Research Study to See How Much CagriSema Lowers Blood Sugar and Body Weight Compared to Placebo in Children and Adolescents With Type 2 Diabetes

RecruitingPhase 3
  • Consano Clinical Research, LLC, Shavano Park · 12 mi away
Ages 10 to 18 · All sexes · Updated Oct 19, 2026 · NCT07282613

A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes

RecruitingPhase 2
  • Quality Research Inc, San Antonio
  • Tekton Research Inc, San Antonio
  • Consano Clin Res-Shavano Park, Shavano Park · 12 mi away
Ages 18 to 75 · All sexes · Updated Oct 7, 2026 · NCT07668388

Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)

RecruitingPhase 2
  • Diabetes & Glandular Disease Clinic, P.A., San Antonio
  • Texas Valley Clinical Research - San Antonio TX, San Antonio
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT07296484

Glycemic and Weight Loss Effects of GLP-1R Agonist Therapy in Subjects With Spinal Cord Injury and Type 2 Diabetes

RecruitingPhase 4
  • University Health - Texas Diabetic Institute, San Antonio
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 70 · All sexes · Updated Oct 5, 2026 · NCT06706284

Research Study on How People With Type 2 Diabetes Tolerate Switching From Semaglutide to Cagrisema

RecruitingPhase 3
  • NE Clin Res of San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT07817251

Pre-diabetes in Subject With Impaired Fasting Glucose (IFG) and Impaired Glucose Tolerance (IGT)

RecruitingHealthy volunteers welcome
  • The University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 22, 2026 · NCT02969798

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, San Antonio
  • AURORA-2 Clinical Site, San Antonio
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

A Research Study Comparing How Well Different Doses of the Medicine NNC0662-0419 Lower Blood Sugar in People With Type 2 Diabetes

RecruitingPhase 2
  • Consano Clinical Research, LLC, Shavano Park · 12 mi away
Ages 18 to 75 · All sexes · Updated Sep 11, 2026 · NCT07415954

AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications

RecruitingPhase 3
  • Clinical Advancement Center, San Antonio
  • The IMA Group IMA Clinical Trials of America Inc. CTA, San Antonio
  • Univ Of Texas Hlth Science Cntr, San Antonio
  • and 2 more
Ages 45 and older · All sexes · Updated Sep 1, 2026 · NCT07797335

Quantifying Hepatic Mitochondrial Fluxes in Humans

RecruitingPhase 4
  • Texas Diabetes Institute - University Health System, San Antonio
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 80 · All sexes · Updated Aug 17, 2026 · NCT05305287

A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin

RecruitingPhase 3
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT07664553

Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes

Recruiting
  • Tekton Research, San Antonio
Ages 18 to 75 · All sexes · Updated Aug 3, 2026 · NCT07521475

SALUD-M: Acceptance Based Coping Skills for Hispanic/Latinx Military Patients With Type 2 Diabetes

Recruiting
  • Brooke Army Medical Center, San Antonio
Ages 18 to 70 · All sexes · Updated Jul 28, 2026 · NCT07674628

SGLT2i, Ketoacidosis, Volume Contraction, and Insulinopenia

RecruitingPhase 1
  • Texas Diabetes Institute/UH, San Antonio
Ages 30 to 75 · All sexes · Updated Jul 17, 2026 · NCT07053306

SGLT2i, Hepatic Glucose Production, and SNS

RecruitingEarly phase 1
  • Texas Diabetes Institute/UH, San Antonio
Ages 30 to 75 · All sexes · Updated Jul 17, 2026 · NCT07053293

SGLT2i, Pioglitazone, and Ketone Production in T2D

RecruitingPhase 1
  • Texas Diabetes Institute/UH, San Antonio
Ages 30 to 75 · All sexes · Updated Jul 17, 2026 · NCT07053319

SGLTi, Hepatic Glucose Production and Ketogenesis

RecruitingPhase 1
  • Texas Diabetes Institute/UH, San Antonio
Ages 30 to 75 · All sexes · Updated Jul 17, 2026 · NCT05960656

HP-211 Safety and Proof of Concept Dose Ranging Study in Patients With Type 2 Diabetes

RecruitingPhase 2
  • Tekton Research, San Antonio
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT07546929

ROME GS System Study

Recruiting
  • Flourish Research - San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Apr 21, 2026 · NCT07518004

Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

RecruitingPhase 3
  • University Health System Texas Diabetic Institute, San Antonio
  • UT Health Science Center, San Antonio
Ages 18 to 75 · All sexes · Updated Mar 10, 2026 · NCT06246799

Acute and Chronic Effects of Oral Ketones in Subjects With HFrEF and Diabetes

RecruitingEarly phase 1
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 18 to 80 · All sexes · Updated Jan 21, 2026 · NCT06108076

About Type 2 Diabetes

Type 2 Diabetes, previously referred to as Adult Onset Diabetes, is the more common type. Risk factors include obesity and family history.

More about Type 2 Diabetes on MedlinePlus

Type 2 Diabetes trials in other cities

Other studies in San Antonio

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.