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Obesity clinical trials in San Antonio, TX

39 studies for Obesity are looking for participants at sites in and around San Antonio (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

RecruitingPhase 3
  • DM Clinical, San Antonio
  • The Texas Liver Institute, San Antonio
  • Pinnacle Clinical Research, San Antonio
  • and 1 more
Ages 8 to 18 · All sexes · Updated Sep 30, 2026 · NCT07253285

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

RecruitingPhase 3
  • VIP Trials, San Antonio
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07595549

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

RecruitingPhase 3
  • Sleep Therapy Research Center, San Antonio
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07668414

Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D

RecruitingPhase 1
  • Endeavor Clinical Trials, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 28, 2026 · NCT07399678

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

RecruitingPhase 3
  • Gastroenterology Research of San Antonio, San Antonio
  • Southern Star Research Institute, San Antonio
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

RecruitingPhase 3
  • Gastroenterology Research of San Antonio, San Antonio
  • Southern Star Research Institute, San Antonio
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

RecruitingPhase 3
  • IMA Clinical Research San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

RecruitingPhase 3
  • Bandera Family Health Care, San Antonio
  • Consano Clinical Research - Shavano Park, Shavano Park · 12 mi away
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

RecruitingPhase 3
  • VIP Trials, San Antonio
  • Endeavor Clinical Trials, San Antonio
  • Consano Clinical Research, LLC, Shavano Park · 12 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

RecruitingPhase 3
  • IMA Clinical Research San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07321886

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

RecruitingPhase 3
  • Research Site, San Antonio
  • Research Site, San Antonio
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

RecruitingPhase 2
  • Endeavor Clinical Trials, San Antonio
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07589608

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

RecruitingPhase 3
  • IMA Clinical Research San Antonio, San Antonio
  • Endeavor Clinical Trials, San Antonio
  • Consano Clinical Research, LLC, Shavano Park · 12 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07392190

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

RecruitingPhase 3
  • Sleep Therapy Research Center, San Antonio
  • Consano Clinical Research, LLC, Shavano Park · 12 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07369011

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

RecruitingPhase 3
  • AURORA-2 Clinical Site, San Antonio
  • AURORA-2 Clinical Site, San Antonio
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

RecruitingPhase 3
  • AURORA-1 Clinical Site, San Antonio
  • AURORA-1 Clinical Site, San Antonio
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

RecruitingPhase 3
  • Pinnacle Clinical Research - San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351058

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

RecruitingPhase 3
  • Pinnacle Clinical Research - South San Antonio, San Antonio
  • IMA Clinical Research - San Antonio, San Antonio
  • Consano Clinical Research, Shavano Park · 12 mi away
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351045

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

RecruitingPhase 2
  • Consano Clinical Research, LLC, Shavano Park · 12 mi away
Ages 18 to 75 · All sexes · Updated Sep 14, 2026 · NCT06897475

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, San Antonio
  • ACCOMPLISH-2 Research Site, San Antonio
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

RecruitingPhase 2
  • Consano Clinical Research, LLC, Shavano Park · 12 mi away
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT07215559

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

RecruitingPhase 2
  • Endeavor Clinical Trials, San Antonio
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT06143956

A First-in-human Research Study on How NNC0721-8060 Works in People Living With Overweight or Obesity

RecruitingPhase 1Healthy volunteers welcome
  • ICON, San Antonio
Ages 18 to 55 · All sexes · Updated Sep 4, 2026 · NCT07767175

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

RecruitingPhase 3
  • Clinical Trials of Texas, San Antonio
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684235

A Study of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase Services, LLC, San Antonio
Ages 18 to 65 · All sexes · Updated Sep 1, 2026 · NCT07654972

Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes

RecruitingPhase 3
  • Kailera Clinical Site, San Antonio
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07284979

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

RecruitingPhase 3
  • Research Site, San Antonio
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07784725

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight

RecruitingPhase 1Healthy volunteers welcome
  • ICON Early Phase Services, San Antonio
Ages 18 to 65 · All sexes · Updated Aug 20, 2026 · NCT07738614

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

RecruitingPhase 3
  • University Hospital, San Antonio
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

RecruitingPhase 3
  • ACCOMPLISH-1 Research Site, San Antonio
Ages 18 to 79 · All sexes · Updated Aug 10, 2026 · NCT07654361

A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia

RecruitingPhase 2
  • Flourish Research - San Antonio Medical Trials, San Antonio
  • Endeavor Clinical Trials, San Antonio
  • Consano Clinical Research, LLC, Shavano Park · 12 mi away
Ages 18 to 80 · All sexes · Updated Jul 22, 2026 · NCT07477704

A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

RecruitingPhase 3
  • VIP Trials_San Antonio, San Antonio
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT07481630

Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation

RecruitingHealthy volunteers welcome
  • South Texas Health Care System, San Antonio, TX, San Antonio
Up to age 80 · All sexes · Updated Jun 1, 2026 · NCT05880108

A Study to Evaluate Tradipitant on Treating Nausea and Vomiting Induced by GLP-1R Agonist Use

RecruitingPhase 3Healthy volunteers welcome
  • Vanda Investigational Site, San Antonio
Ages 18 to 65 · All sexes · Updated Apr 20, 2026 · NCT07446439

Effects of Tirzepatide on Muscle and Vascular Health in Obese Older Adults

RecruitingPhase 2
  • University of Texas Health Science Center at San Antonio, San Antonio
Ages 50 and older · All sexes · Updated Apr 15, 2026 · NCT06811324

About Obesity

Read about the causes of obesity and find out what you can do to decrease your risk of its associated health issues.

More about Obesity on MedlinePlus

Obesity trials in other cities

Other studies in San Antonio

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.