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Lupus clinical trials in Houston, TX

14 studies for Lupus are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythematosus

RecruitingPhase 3
  • Research Site, Houston
Ages 18 to 70 · All sexes · Updated Nov 13, 2026 · NCT07430306

A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)

RecruitingPhase 2
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 to 74 · All sexes · Updated Nov 12, 2026 · NCT07409181

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

RecruitingObservational study
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT04751396

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
  • UT MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT03816345

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

RecruitingPhase 3
  • Novel Research LLC, Bellaire · 7 mi away
Ages 12 to 100 · All sexes · Updated Nov 9, 2026 · NCT06133972

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2)

RecruitingPhase 3
  • Prolato Clinical Research Center, Houston
  • Accurate Clinical Research, Humble · 17 mi away
Ages 18 to 75 · All sexes · Updated Nov 4, 2026 · NCT07355218

Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT06434363

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

RecruitingPhase 3
  • Sl0044 50696, Houston
  • Sl0044 50723, Houston
  • Sl0044 50738, Bellaire · 7 mi away
Ages 16 and older · All sexes · Updated Nov 2, 2026 · NCT06617325

Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)

RecruitingPhase 2
  • Texas Children's Hospital, Houston
Ages 12 to 65 · All sexes · Updated Oct 30, 2026 · NCT07053800

Dose Escalation Study With Bispecific Antibodies in Adult Participants With Lupus Nephritis

RecruitingPhase 1
  • Baylor College of Medicine, Houston
Ages 18 to 60 · All sexes · Updated Oct 27, 2026 · NCT06975787

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

RecruitingPhase 1/2
  • University of Texas MD Anderson Cancer Center, Houston
Ages 12 to 65 · All sexes · Updated Oct 6, 2026 · NCT06121297

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

RecruitingPhase 3
  • Research Site, Houston
Ages 5 to 17 · All sexes · Updated Sep 30, 2026 · NCT05835310

A Research Trial to Assess if Cenerimod is Efficacious and Safe to Treat Active Lupus Nephritis on Top of Regular Treatment

RecruitingPhase 3
  • Novel Research, LLC., Houston
  • Northwest Houston Arthritis, Houston
  • Rheumatology Care Center, PLLC, Bellaire · 7 mi away
Ages 18 to 75 · All sexes · Updated Jul 30, 2026 · NCT07201129

About Lupus

Lupus is an autoimmune disease that causes your immune system to attack your healthy tissues and cells. This can cause damage to many parts of your body.

More about Lupus on MedlinePlus

Lupus trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.