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Lupus clinical trials in Chicago, IL

8 studies for Lupus are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Phase IIa Study of ICG318 CAR-T in Refractory Systemic Lupus Erythematosus With or Without Lupus Nephritis

RecruitingPhase 2
  • University of Chicago, Chicago
Ages 16 to 70 · All sexes · Updated Sep 17, 2026 · NCT07328581

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

RecruitingPhase 1
  • The University of Chicago Medical Center, Chicago
Ages 18 to 74 · All sexes · Updated Sep 10, 2026 · NCT07085104

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

RecruitingPhase 3
  • Research Site, Chicago
  • Research Site, Chicago
Ages 5 to 17 · All sexes · Updated Sep 10, 2026 · NCT05835310

A Study to Investigate the Safety, Tolerability, and Efficacy of AZD0120 in Adults With Refractory SLE

RecruitingPhase 1/2
  • Research Site, Chicago
Ages 18 to 70 · All sexes · Updated Sep 10, 2026 · NCT06897930

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

RecruitingPhase 3
  • Sl0044 50699, Chicago
Ages 16 and older · All sexes · Updated Sep 4, 2026 · NCT06617325

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

RecruitingPhase 1
  • Northwestern Medicine, Robert H. Lurie Comprehensive Cancer Center, Chicago
Ages 18 to 70 · All sexes · Updated Aug 28, 2026 · NCT06925542

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

RecruitingPhase 1/2
  • Northwestern Memorial Hospital, Chicago
  • The University of Chicago Medical Center, Chicago
Ages 18 to 65 · All sexes · Updated Aug 26, 2026 · NCT06121297

Lupus Landmark Study: A Prospective Registry and Biorepository

RecruitingObservational study
  • University of Chicago, Chicago
Ages 18 to 110 · All sexes · Updated Apr 15, 2026 · NCT05934149

About Lupus

Lupus is an autoimmune disease that causes your immune system to attack your healthy tissues and cells. This can cause damage to many parts of your body.

More about Lupus on MedlinePlus

Lupus trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.