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Major Depressive Disorder clinical trials in Phoenix, AZ

7 studies for Major Depressive Disorder are looking for participants at sites in and around Phoenix (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 2
  • IMA Clinical Research- Phoenix, Phoenix
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237

Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder

RecruitingPhase 3
  • Vanda Investigational Site, Phoenix
Ages 18 to 65 · All sexes · Updated Sep 24, 2026 · NCT06830044

A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

RecruitingPhase 2
  • Draig Clinical Site, Phoenix
Ages 18 to 75 · All sexes · Updated Sep 2, 2026 · NCT07610473

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

RecruitingPhase 3
  • IMA Clinical Research Phoenix, Phoenix
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

RecruitingPhase 2
  • NoesisPharma, LLC, Phoenix
Ages 18 to 64 · All sexes · Updated Jul 27, 2026 · NCT07115329

A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder

RecruitingPhase 2
  • Ima Clinical Research Phoenix (Alea) /ID# 277516, Phoenix
Ages 18 to 65 · All sexes · Updated Jun 15, 2026 · NCT07276997

Study of ALTO-300 in MDD

RecruitingPhase 2
  • Site 200, Phoenix
Ages 18 to 70 · All sexes · Updated Jul 24, 2025 · NCT05922878

Major Depressive Disorder trials in other cities

Other studies in Phoenix

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.