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Melanoma clinical trials in Omaha, NE

12 studies for Melanoma are looking for participants at sites in and around Omaha (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)

RecruitingPhase 3
  • Oncology Hematology West P.C. dba Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06246916

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

RecruitingPhase 2
  • Nebraska Medicine-Village Pointe, Omaha
  • University of Nebraska Medical Center, Omaha
  • Nebraska Medicine-Bellevue, Bellevue · 9 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma

RecruitingPhase 3
  • Alegent Health Immanuel Medical Center, Omaha
  • Alegent Health Bergan Mercy Medical Center, Omaha
  • Alegent Health Lakeside Hospital, Omaha
Ages 75 and older · All sexes · Updated Sep 24, 2026 · NCT07068074

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Alegent Health Immanuel Medical Center, Omaha
  • Alegent Health Bergan Mercy Medical Center, Omaha
  • Alegent Health Lakeside Hospital, Omaha
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Children's Hospital and Medical Center of Omaha, Omaha
  • University of Nebraska Medical Center, Omaha
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

Integrated Cancer Repository for Cancer Research

RecruitingObservational studyHealthy volunteers welcome
  • Methodist Estabrook Cancer Center, Omaha
  • Nebraska Methodist Health System, Omaha
  • University of Nebraska Medical Center, Omaha
  • and 1 more
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma

RecruitingPhase 1/2
  • Nebraska Cancer Specialists, Omaha
Ages 18 to 90 · All sexes · Updated Jun 10, 2026 · NCT05655312

Neoadjuvant Darovasertib in Primary Uveal Melanoma

RecruitingPhase 3
  • TIERING Percentiles, Omaha
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT07015190

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Omaha
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of Nebraska Medical Center, Omaha
Ages 18 and older · All sexes · Updated May 18, 2025 · NCT05970497

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

Recruiting
  • Nebraska Medicine-Village Pointe, Omaha
  • University of Nebraska Medicine, Omaha
  • Nebraska Medicine - Bellevue, Bellevue · 9 mi away
Ages 18 and older · All sexes · Updated Nov 27, 2024 · NCT03860883

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Omaha

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.