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Mild Cognitive Impairment clinical trials in California

41 studies for Mild Cognitive Impairment are looking for participants at sites in California.

Cities in California

A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)

  • Progeny Psychiatric Clinic - Irvine, Irvine
  • ATP Clinical Research, Inc - Orange, Orange
RecruitingPhase 4
Ages 50 and older · All sexes · Updated Sep 25, 2026 · NCT07633470

A Study of LY3439539 in Participants With Alzheimer's Disease

  • Irvine Clinical Research, Irvine
  • Healthy Brain Clinic, Long Beach
  • Inglewood Clinical, Los Angeles
  • and 1 more
RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Sep 24, 2026 · NCT07598370

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

  • Profound Research LLC, Carlsbad
  • Irvine Clinical Research, Irvine
  • UCSD - Altman Clinical and Translational Research Institute (ACTRI), La Jolla
  • and 1 more
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Sep 22, 2026 · NCT07589595

Predicting Pre-dementia

  • Foster Carr MD, San Diego
RecruitingObservational studyHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Sep 22, 2026 · NCT07516119

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

  • Sun Valley Research Center, Inc., Imperial
  • Irvine Center for Clinical Research, Irvine
  • Healthy Brain Clinic, Long Beach
  • and 5 more
RecruitingPhase 3
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

  • Fullerton Neurology and Headache Center, Fullerton
  • Irvine Clinical Research, Irvine
  • Inglewood Clinical, Los Angeles
  • and 1 more
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Sep 17, 2026 · NCT06976203

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

  • Kaiser Permanente Los Angeles Medical Center, Los Angeles
  • Cedars Sinai Medical Center, Los Angeles
  • University of California Los Angeles, Los Angeles
  • and 1 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04916210

Alzheimer's Tau Platform: Master Protocol

  • University of California, San Francisco, San Francisco
RecruitingPhase 2
Ages 50 to 80 · All sexes · Updated Sep 8, 2026 · NCT06957418

Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders

  • Saddleback Medical Center, Orange
Recruiting
Ages 70 and older · All sexes · Updated Sep 8, 2026 · NCT05929703

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

  • Fresno VA Medical Center, Fresno
  • Long Beach VA Medical Center, Long Beach
  • Cedars-Sinai Medical Center, Los Angeles
  • and 3 more
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Enhancing Attention and Wellbeing Using Digital Therapeutics

  • University of California San Francisco, San Francisco
RecruitingHealthy volunteers welcome
Ages 60 to 99 · All sexes · Updated Aug 24, 2026 · NCT06397469

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

  • Healthy Brain Clinic, Long Beach
  • Anderson Clinical Research, Redlands
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Aug 20, 2026 · NCT06976216

Senicapoc in Alzheimer's Disease

  • University of California, Davis Alzheimer's Disease Center, Sacramento
  • UC Davis Alzheimer's Disease Center East Bay, Walnut Creek
RecruitingPhase 2Healthy volunteers welcome
Ages 55 to 85 · All sexes · Updated Aug 17, 2026 · NCT04804241

Interventions in Mathematics and Cognitive Skills

  • Stanford Cognitive and Systems Neuroscience Laboratory, Palo Alto
RecruitingHealthy volunteers welcome
Ages 6 to 12 · All sexes · Updated Aug 11, 2026 · NCT05201534

Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease

  • The Regenesis Project, Santa Monica
Recruiting
Ages 22 to 80 · All sexes · Updated Jul 31, 2026 · NCT07207122

Effects of Accelerated rTMS on Cognitive Function

  • San Francisco Neurology and Sleep Center, San Francisco
Recruiting
Ages 50 to 90 · All sexes · Updated Jul 17, 2026 · NCT07547319

Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT

  • Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange
RecruitingPhase 1/2
Ages 18 and older · Women · Updated Jul 17, 2026 · NCT04520139

Rehabilitation and Longitudinal Follow-up of Cognition in Adult Lower Grade Gliomas

  • University of California, San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT03948490

Brain Health in Breast Cancer Survivors

  • University of California at Los Angeles, Los Angeles
RecruitingObservational studyHealthy volunteers welcome
Ages 35 to 65 · Women · Updated Jul 7, 2026 · NCT04297020

A Study to Evaluate KYN-5356 in Adults With Cognitive Impairment Associated With Schizophrenia

  • Synapse Clinical Trials, Cerritos
  • Synergy Research Center, Lemon Grove
  • Cenexel CNS, Los Alamitos
RecruitingPhase 2
Ages 18 to 55 · All sexes · Updated Jun 23, 2026 · NCT07191483

Polyphenols and Cognitive Decline

  • University of California, Los Angeles, Los Angeles
RecruitingHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Jun 11, 2026 · NCT06507254

Effect of Gerofit Exercise on Cognition in Older Veterans

  • VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles
RecruitingHealthy volunteers welcome
Ages 65 and older · All sexes · Updated Jun 2, 2026 · NCT06107842

TREAD: Time Restricted Eating Intervention for Alzheimer's Disease

  • Shiley Marcos Alzheimer's Disease Center, San Diego
RecruitingPhase 1Healthy volunteers welcome
Ages 60 and older · All sexes · Updated May 26, 2026 · NCT06548191

Preventing Medication Mismanagement in People Living With Dementia

  • HiDO Technologies, Folsom
Recruiting
Ages 65 and older · All sexes · Updated May 22, 2026 · NCT07600684

Wayfinding Intervention and Long-Term Memory

  • UCSF Mission Bay, San Francisco
RecruitingHealthy volunteers welcome
Ages 60 to 85 · All sexes · Updated May 7, 2026 · NCT05625425

BID LTM Digital Intervention in Aging

  • University of California, San Francsico, San Francisco
Recruiting
Ages 60 to 85 · All sexes · Updated Apr 2, 2026 · NCT06916221

BID WM Digital Intervention in Aging

  • University of California, San Francisco, San Francisco
RecruitingHealthy volunteers welcome
Ages 60 to 85 · All sexes · Updated Apr 1, 2026 · NCT06918704

Effects of Sabroxy® Supplementation on Insulin Resistance and Cognitive Function in Adults With Mild Cognitive Impairment and Insulin Resistance

  • San Francisco Research Institute, San Francisco
RecruitingHealthy volunteers welcome
Ages 40 to 80 · All sexes · Updated Jan 28, 2026 · NCT07220694

Biomarker Exploration in Aging, Cognition and Neurodegeneration

  • University of California, Irvine, Irvine
RecruitingPhase 3Healthy volunteers welcome
Ages 60 and older · All sexes · Updated Jan 23, 2026 · NCT03860857

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

  • University of California, Los Angeles
  • University of California, San Francisco
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT05677880

Study of ALTO-101 in Patients With Schizophrenia

  • Site 5038, Garden Grove
  • Site 5063, Los Angeles
  • Site 5106, Orange
  • and 1 more
RecruitingPhase 2
Ages 21 to 55 · All sexes · Updated Dec 26, 2025 · NCT06502964

The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia

  • University of California San Francisco, San Francisco
Recruiting
Ages 55 to 89 · All sexes · Updated Dec 11, 2025 · NCT04171323

Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study

  • CSMC, Los Angeles
Recruiting
Ages 55 to 89 · All sexes · Updated Nov 19, 2025 · NCT07224607

Strengthening Neuro-Cognitive Skills for Success in School, Work and Beyond

  • VA Northern California Health Care System, Mather, CA, Sacramento
Recruiting
Ages 21 to 60 · All sexes · Updated Nov 17, 2025 · NCT04109027

Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)

  • Naval Medical Center San Diego, San Diego
Recruiting
Ages 18 to 60 · All sexes · Updated Nov 12, 2025 · NCT06413173

TabCAT Brain Health Assessment in Primary Care

  • Kaiser Permanente Southern California Department of Research & Evaluation, Pasadena
Recruiting
Ages 18 and older · All sexes · Updated Oct 31, 2025 · NCT06090578

Combined STN and NBM Deep Brain Stimulation for Mild Cognitive Impairment in Parkinson's Disease

  • Stanford Neuroscience Health Center, Stanford
Recruiting
Ages 21 to 80 · All sexes · Updated May 30, 2025 · NCT05968703

Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease

  • Neurobehavioral Systems, Inc., Berkeley
RecruitingHealthy volunteers welcome
Ages 18 to 89 · All sexes · Updated May 22, 2025 · NCT04800588

Remimazolam for Cataract Surgery

  • Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine, Los Angeles
RecruitingPhase 4
Ages 65 and older · All sexes · Updated Mar 19, 2025 · NCT05980117

Study Evaluating the Quality and Effects of Lion's Mane Product on Cognitive Health

  • People Science, Los Angeles
RecruitingObservational study
Ages 40 to 75 · All sexes · Updated Mar 11, 2025 · NCT06870136

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.