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Mild Cognitive Impairment clinical trials in California
41 studies for Mild Cognitive Impairment are looking for participants at sites in California.
Cities in California
- Los Angeles12 studies
- San Francisco11 studies
- Irvine6 studies
- San Diego6 studies
- Mountain View5 studies
- Long Beach4 studies
- Orange4 studies
Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
- Neurobehavioral Systems, Inc., Berkeley
RecruitingHealthy volunteers welcome
Ages 18 to 89 · All sexes · Updated Nov 13, 2026 · NCT04800588Remotely Supervised tDCS+ for Complex Attention in mTBI (Cognetric)
- Naval Medical Center San Diego, San Diego
Recruiting
Ages 18 to 60 · All sexes · Updated Nov 13, 2026 · NCT06413173CMN LIFU for Enhanced Amyloid Reduction (CLEART Study)
- University of California San Francisco, San Francisco
Recruiting
Ages 65 and older · All sexes · Updated Nov 9, 2026 · NCT07866768A Study of LY3439539 in Participants With Alzheimer's Disease
- Irvine Clinical Research, Irvine
- Healthy Brain Clinic, Long Beach
- Inglewood Clinical, Los Angeles
- and 1 more
RecruitingPhase 1
Ages 50 to 85 · All sexes · Updated Nov 4, 2026 · NCT07598370A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
- Profound Research LLC, Carlsbad
- Irvine Clinical Research, Irvine
- UCSD - Altman Clinical and Translational Research Institute (ACTRI), La Jolla
- and 1 more
RecruitingPhase 2
Ages 55 to 85 · All sexes · Updated Nov 4, 2026 · NCT07589595A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
- Healthy Brain Clinic, Long Beach
- Anderson Clinical Research, Redlands
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Oct 27, 2026 · NCT06976216Alzheimer's Tau Platform: Master Protocol
- University of California, San Francisco, San Francisco
RecruitingPhase 2
Ages 50 to 80 · All sexes · Updated Oct 26, 2026 · NCT06957418Strengthening Neuro-Cognitive Skills for Success in School, Work and Beyond
- VA Northern California Health Care System, Mather, CA, Sacramento
Recruiting
Ages 21 to 60 · All sexes · Updated Oct 21, 2026 · NCT04109027Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
- Sun Valley Research Center, Inc., Imperial
- Irvine Center for Clinical Research, Irvine
- Healthy Brain Clinic, Long Beach
- and 5 more
RecruitingPhase 3
Ages 50 to 90 · All sexes · Updated Oct 19, 2026 · NCT07177352A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
- Progeny Psychiatric Clinic - Irvine, Irvine
- ATP Clinical Research, Inc - Orange, Orange
RecruitingPhase 4
Ages 50 and older · All sexes · Updated Oct 19, 2026 · NCT07633470Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study
- CSMC, Los Angeles
Recruiting
Ages 55 to 89 · All sexes · Updated Oct 13, 2026 · NCT07224607A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
- Fullerton Neurology and Headache Center, Fullerton
- Irvine Clinical Research, Irvine
- Inglewood Clinical, Los Angeles
- and 1 more
RecruitingPhase 3
Ages 60 to 85 · All sexes · Updated Oct 8, 2026 · NCT06976203Predicting Pre-dementia
- Foster Carr MD, San Diego
RecruitingObservational studyHealthy volunteers welcome
Ages 55 and older · All sexes · Updated Sep 22, 2026 · NCT07516119Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY
- Kaiser Permanente Los Angeles Medical Center, Los Angeles
- Cedars Sinai Medical Center, Los Angeles
- University of California Los Angeles, Los Angeles
- and 1 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04916210Evaluating Novel Healthcare Approaches to Nurturing and Caring for Hospitalized Elders
- Saddleback Medical Center, Orange
Recruiting
Ages 70 and older · All sexes · Updated Sep 8, 2026 · NCT05929703Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
- Fresno VA Medical Center, Fresno
- Long Beach VA Medical Center, Long Beach
- Cedars-Sinai Medical Center, Los Angeles
- and 3 more
RecruitingPhase 4Healthy volunteers welcome
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206Enhancing Attention and Wellbeing Using Digital Therapeutics
- University of California San Francisco, San Francisco
RecruitingHealthy volunteers welcome
Ages 60 to 99 · All sexes · Updated Aug 24, 2026 · NCT06397469Senicapoc in Alzheimer's Disease
- University of California, Davis Alzheimer's Disease Center, Sacramento
- UC Davis Alzheimer's Disease Center East Bay, Walnut Creek
RecruitingPhase 2Healthy volunteers welcome
Ages 55 to 85 · All sexes · Updated Aug 17, 2026 · NCT04804241Interventions in Mathematics and Cognitive Skills
- Stanford Cognitive and Systems Neuroscience Laboratory, Palo Alto
RecruitingHealthy volunteers welcome
Ages 6 to 12 · All sexes · Updated Aug 11, 2026 · NCT05201534Effects of Transcranial Focused Ultrasound Stimulation (tFUS) on Neurological and Cognitive Outcomes in Parkinson's Disease
- The Regenesis Project, Santa Monica
Recruiting
Ages 22 to 80 · All sexes · Updated Jul 31, 2026 · NCT07207122Effects of Accelerated rTMS on Cognitive Function
- San Francisco Neurology and Sleep Center, San Francisco
Recruiting
Ages 50 to 90 · All sexes · Updated Jul 17, 2026 · NCT07547319Effect of NAC on Preventing Chemo-Related Cognitive Impairments in Ovarian Ca Pts Treated W/ PBT
- Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange
RecruitingPhase 1/2
Ages 18 and older · Women · Updated Jul 17, 2026 · NCT04520139Rehabilitation and Longitudinal Follow-up of Cognition in Adult Lower Grade Gliomas
- University of California, San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Jul 14, 2026 · NCT03948490Brain Health in Breast Cancer Survivors
- University of California at Los Angeles, Los Angeles
RecruitingObservational studyHealthy volunteers welcome
Ages 35 to 65 · Women · Updated Jul 7, 2026 · NCT04297020Polyphenols and Cognitive Decline
- University of California, Los Angeles, Los Angeles
RecruitingHealthy volunteers welcome
Ages 50 and older · All sexes · Updated Jun 11, 2026 · NCT06507254Effect of Gerofit Exercise on Cognition in Older Veterans
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles
RecruitingHealthy volunteers welcome
Ages 65 and older · All sexes · Updated Jun 2, 2026 · NCT06107842TREAD: Time Restricted Eating Intervention for Alzheimer's Disease
- Shiley Marcos Alzheimer's Disease Center, San Diego
RecruitingPhase 1Healthy volunteers welcome
Ages 60 and older · All sexes · Updated May 26, 2026 · NCT06548191Preventing Medication Mismanagement in People Living With Dementia
- HiDO Technologies, Folsom
Recruiting
Ages 65 and older · All sexes · Updated May 22, 2026 · NCT07600684Wayfinding Intervention and Long-Term Memory
- UCSF Mission Bay, San Francisco
RecruitingHealthy volunteers welcome
Ages 60 to 85 · All sexes · Updated May 7, 2026 · NCT05625425BID LTM Digital Intervention in Aging
- University of California, San Francsico, San Francisco
Recruiting
Ages 60 to 85 · All sexes · Updated Apr 2, 2026 · NCT06916221BID WM Digital Intervention in Aging
- University of California, San Francisco, San Francisco
RecruitingHealthy volunteers welcome
Ages 60 to 85 · All sexes · Updated Apr 1, 2026 · NCT06918704Effects of Sabroxy® Supplementation on Insulin Resistance and Cognitive Function in Adults With Mild Cognitive Impairment and Insulin Resistance
- San Francisco Research Institute, San Francisco
RecruitingHealthy volunteers welcome
Ages 40 to 80 · All sexes · Updated Jan 28, 2026 · NCT07220694Biomarker Exploration in Aging, Cognition and Neurodegeneration
- University of California, Irvine, Irvine
RecruitingPhase 3Healthy volunteers welcome
Ages 60 and older · All sexes · Updated Jan 23, 2026 · NCT03860857Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study
- University of California, Los Angeles
- University of California, San Francisco
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Jan 15, 2026 · NCT05677880Study of ALTO-101 in Patients With Schizophrenia
- Site 5038, Garden Grove
- Site 5063, Los Angeles
- Site 5106, Orange
- and 1 more
RecruitingPhase 2
Ages 21 to 55 · All sexes · Updated Dec 26, 2025 · NCT06502964The Active Mind Trial: An Adaptive Randomized Trial to Improve Function and Delay Dementia
- University of California San Francisco, San Francisco
Recruiting
Ages 55 to 89 · All sexes · Updated Dec 11, 2025 · NCT04171323TabCAT Brain Health Assessment in Primary Care
- Kaiser Permanente Southern California Department of Research & Evaluation, Pasadena
Recruiting
Ages 18 and older · All sexes · Updated Oct 31, 2025 · NCT06090578Combined STN and NBM Deep Brain Stimulation for Mild Cognitive Impairment in Parkinson's Disease
- Stanford Neuroscience Health Center, Stanford
Recruiting
Ages 21 to 80 · All sexes · Updated May 30, 2025 · NCT05968703Remimazolam for Cataract Surgery
- Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine, Los Angeles
RecruitingPhase 4
Ages 65 and older · All sexes · Updated Mar 19, 2025 · NCT05980117Study Evaluating the Quality and Effects of Lion's Mane Product on Cognitive Health
- People Science, Los Angeles
RecruitingObservational study
Ages 40 to 75 · All sexes · Updated Mar 11, 2025 · NCT06870136From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.