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Obesity clinical trials in Minnesota

28 studies for Obesity are looking for participants at sites in Minnesota.

Cities in Minnesota

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

  • University of Minnesota Masonic Children's Hospital, Minneapolis
  • Mayo Clinic - PIN, Rochester
  • Children's Minnesota Pediatric Endocrinology Clinic & McNeeley Diabetes Center, Saint Paul
RecruitingPhase 3
Ages 6 to 17 ยท All sexes ยท Updated Sep 24, 2026 ยท NCT06672549

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

  • Fairview Health Services M Health Fairview St Johns Hospital, Maplewood
  • Minneapolis Heart Institute Foundation, Minneapolis
RecruitingPhase 3
Ages 45 to 99 ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07037433

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

  • Headlands Research-Twin Cities, Maplewood
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 22, 2026 ยท NCT07369011

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

  • AURORA-2 Clinical Site, Mankato
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07743450

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  • Mankato Clinic, Mankato
  • Fairview Health Services M Health Fairview St Johns Hospital, Maplewood
  • University of Minnesota, Minneapolis
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07037459

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

  • International Diabetes Center At Park Nicollet, Minneapolis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 14, 2026 ยท NCT07351045

First-in-human Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of ACCG-2671

  • Research Site, Dilworth
RecruitingPhase 1/2Healthy volunteers welcome
Ages 25 to 75 ยท All sexes ยท Updated Sep 14, 2026 ยท NCT07815678

Exercise Response in Humans With Obesity

  • Mayo Clinic in Rochester, Rochester
RecruitingObservational study
Ages 20 to 45 ยท All sexes ยท Updated Sep 11, 2026 ยท NCT05857150

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

  • ACCOMPLISH-2 Research Site, Mankato
  • ACCOMPLISH-2 Research Site, Minneapolis
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 79 ยท All sexes ยท Updated Sep 11, 2026 ยท NCT07654374

tDCS With Cognitive Training to Reduce Impulsivity and Weight in Veterans With Obesity

  • Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis
Recruiting
Ages 18 to 80 ยท All sexes ยท Updated Sep 8, 2026 ยท NCT05225233

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

  • International Diabetes Center, Minneapolis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 4, 2026 ยท NCT07533175

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

  • University of Minnesota, Minneapolis
  • Synexus Clinical Research US-MN, Richfield
RecruitingPhase 3
Ages 8 to 18 ยท All sexes ยท Updated Aug 31, 2026 ยท NCT07253285

A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight

  • International Diabetes Center, Minneapolis
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 31, 2026 ยท NCT07564414

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

  • Children's Hospitals and Clinics of Minnesota, Minneapolis
RecruitingPhase 2
Ages 7 to 25 ยท All sexes ยท Updated Aug 19, 2026 ยท NCT05082519

Efficacy and Safety of Aleniglipron in Participants With Obesity or Overweight With a Weight-Related Comorbidity (ACCOMPLISH-1)

  • ACCOMPLISH-1 Research Site, Mankato
  • ACCOMPLISH-1 Research Site, Richfield
RecruitingPhase 3
Ages 18 to 79 ยท All sexes ยท Updated Aug 10, 2026 ยท NCT07654361

Upper Body Subcutaneous Exosome Release in Response to a Meal in Obesity

  • Mayo Clinic in Rochester, Rochester
RecruitingHealthy volunteers welcome
Ages 18 to 55 ยท All sexes ยท Updated Aug 5, 2026 ยท NCT07031297

Fibrosis Lessens After Metabolic Surgery

  • Mayo Clinic, Rochester
RecruitingPhase 4Healthy volunteers welcome
Ages 18 to 75 ยท All sexes ยท Updated Jul 31, 2026 ยท NCT06374875

A Proof-of-Concept Study to Evaluate Topical-Lingual Semaglutide in Adults With Obesity

  • Clinical Research Institute of Minnesota, Minneapolis
RecruitingPhase 4
Ages 18 to 65 ยท All sexes ยท Updated Jul 27, 2026 ยท NCT07728383

Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention

  • Minneapolis VA Health Care System, Minneapolis
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 22, 2026 ยท NCT06390345

Phenotype-Tailored Lifestyle Intervention for Obesity: A Randomized Trial

  • Mayo Clinic, Rochester
Recruiting
Ages 18 to 65 ยท All sexes ยท Updated Jun 11, 2026 ยท NCT06770049

Regional Lipolysis and Adipocyte Lipolysis Protein Stimulation

  • Mayo Clinic in Rochester, Rochester
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 65 ยท All sexes ยท Updated May 22, 2026 ยท NCT06416969

Circadian Rhythms in Human Adipose

  • Mayo Clinic, Rochester
RecruitingHealthy volunteers welcome
Ages 18 to 55 ยท All sexes ยท Updated Apr 14, 2026 ยท NCT06891534

Regional Lipolysis Insulin Regulation

  • Mayo Clinic in Rochester, Rochester
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 65 ยท All sexes ยท Updated Apr 13, 2026 ยท NCT06392854

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder

  • Mayo Clinic, Rochester
RecruitingPhase 4Mentions payment for participants
Ages 18 to 65 ยท All sexes ยท Updated Mar 11, 2026 ยท NCT07213466

Insulin Regulation of Lipolysis and Lipolysis Proteins

  • Mayo Clinic in Rochester, Rochester
RecruitingEarly phase 1Healthy volunteers welcome
Ages 18 to 55 ยท All sexes ยท Updated Jan 28, 2026 ยท NCT03866408

Project SHINE (Sleep Health INitiative for Equity): Culturally Informing a Sleep Extension Intervention for African American Adults

  • University of Minnesota, Minneapolis
RecruitingPhase 1/2
Ages 21 to 75 ยท All sexes ยท Updated Dec 17, 2025 ยท NCT06226077

Weight Loss Through Mayo Clinic Diet

  • Mayo Clinic in Rochester, Rochester
RecruitingHealthy volunteers welcome
Ages 18 to 64 ยท All sexes ยท Updated Oct 7, 2025 ยท NCT06862375

Tirzepatide in PWS, HO and GNSO

  • Children's Minnesota, Saint Paul
RecruitingPhase 4
Ages 18 to 26 ยท All sexes ยท Updated Sep 16, 2025 ยท NCT06901245

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.