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Prostate Cancer clinical trials in California
156 studies for Prostate Cancer are looking for participants at sites in California.
Cities in California
- Los Angeles61 studies
- San Francisco45 studies
- San Diego31 studies
- Baldwin Park30 studies
- Sacramento19 studies
- Mountain View15 studies
- Santa Monica15 studies
- Orange14 studies
- Irvine14 studies
- Santa Rosa9 studies
- Roseville8 studies
- Long Beach7 studies
- Santa Maria7 studies
- Oakland6 studies
- Stockton6 studies
- Newport Beach6 studies
- Arden-Arcade6 studies
- San Jose6 studies
- Pleasanton6 studies
- Concord6 studies
- Burbank5 studies
- Santa Clara5 studies
- Modesto5 studies
- Vallejo5 studies
- Fresno5 studies
- Fremont5 studies
- Richmond5 studies
- Elk Grove4 studies
- Alhambra4 studies
- Redwood City4 studies
- San Leandro4 studies
- Daly City4 studies
- Torrance3 studies
- Napa3 studies
- Indio3 studies
- Vacaville3 studies
- Antioch3 studies
- Santa Barbara3 studies
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
- University of San Diego Moores Cancer Center, La Jolla
- UCLA Jonsson Comprehensive Cancer Center, Los Angeles
- USC Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750Testing the Addition of Docetaxel (Chemotherapy) to the Usual Treatment (Hormonal Therapy and Apalutamide) for Metastatic Prostate Cancer, ASPIRE Trial
- Kaiser Permanente Dublin, Dublin
- Kaiser Permanente-Fremont, Fremont
- Kaiser Permanente Fresno Orchard Plaza, Fresno
- and 18 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT06931340Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial
- AIS Cancer Center at San Joaquin Community Hospital, Bakersfield
- UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
- City of Hope at Irvine Lennar, Irvine
- and 5 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Oct 2, 2026 · NCT07200830Distance-Based Exercise to Preserve Function and Prevent Disability
- Kaiser Permanente Dublin, Dublin
- Kaiser Permanente-Fremont, Fremont
- Kaiser Permanente Fresno Orchard Plaza, Fresno
- and 10 more
Recruiting
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
- City of Hope National Medical Center, Duarte
- University of California, San Diego (UCSD) - Moores Cancer Center, La Jolla
- UCLA Department of Medicine-Hematology/Oncology, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- Mission Hope Medical Oncology - Arroyo Grande, Arroyo Grande
- PCR Oncology, Arroyo Grande
- AIS Cancer Center at San Joaquin Community Hospital, Bakersfield
- and 20 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial
- Enloe Medical Center, Chico
- UC San Diego Health System - Encinitas, Encinitas
- UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine
- and 4 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06632977A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
- City of Hope, Duarte
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478Study of AR Suppression With Carotuximab in Metastatic, Castration-Resistant Prostate Canc
- City of Hope, Duarte
- Cedars-Sinai Medical Center, Los Angeles
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 30, 2026 · NCT05534646Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors
- Keck Medicine of USC Koreatown, Los Angeles
- Los Angeles General Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
- and 1 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT03866382Impact of Fluciclovine (18F) PET (Positron Emission Tomography) on the Management of Prostate Cancer Following Negative or Equivocal PSMA (Prostate-Specific Membrane Antigen) PET Imaging at the Time of Biochemical Recurrence
- University of California San Diego Health, San Diego
RecruitingPhase 4
Ages 18 and older · Men · Updated Sep 29, 2026 · NCT07569926An Investigational Scan (Flotufolastat F 18 PET/CT) for Detecting Residual or Recurrent Disease in Patients Who Completed Focal Therapy for Prostate Cancer.
- UCLA / Jonsson Comprehensive Cancer Center, Los Angeles
RecruitingPhase 2
Ages 18 to 90 · Men · Updated Sep 29, 2026 · NCT07185165Precision-Based Genomics in Prostate Cancer
- University of California San Diego, La Jolla
- University of California San Francisco, San Francisco
RecruitingObservational study
Ages 18 to 120 · Men · Updated Sep 28, 2026 · NCT04706663Prostate Cancer Risk Identification in a Multi-Ethnic Cohort: a Prospective US-based Multi-center Validation Study of Proclarix
- Om Research, San Diego
RecruitingObservational study
Ages 40 to 75 · Men · Updated Sep 28, 2026 · NCT07543757DESTINY-PANTUMOUR04
- Research Site, San Diego
RecruitingObservational study
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer
- Research Site, Los Angeles
RecruitingPhase 1/2
Ages 18 to 130 · Men · Updated Sep 25, 2026 · NCT07181161Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer
- University of California San Diego, Moores Cancer Center, La Jolla
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06801236A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004)
- CHAO Family Comprehensive Cancer Center and Ambulatory Care ( Site 0120), Irvine
- UCLA Hematology/Oncology - Santa Monica ( Site 0044), Los Angeles
- University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0040), Orange
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06136650This Study Will Explore Whether a Combination of the Investigational Drug Mevrometostat (PF-06821497) and Enzalutamide Will Work Better Than Taking Enzalutamide Alone in Participants With mCSPC Who Are ARPI naïve.
- UCLA Hematology/Oncology - Alhambra, Alhambra
- UCLA Hematology/Oncology - Atascadero, Atascadero
- Cedars-Sinai Cancer Beverly Hills (drug treatment and dispensing location), Beverly Hills
- and 20 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07028853A Study in Patients With Metastatic Castration-Resistant Prostate Cancer
- START Los Angeles, Los Angeles
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 24, 2026 · NCT07719361Open-label Study Comparing AAA817 Versus Standard of Care in the Treatment of Previously Treated PSMA-positive mCRPC Adults Who Have Disease Progressed on or After [177Lu]Lu-PSMA Targeted Therapy
- VA Greater LA Healthcare System, Los Angeles
- VA Palo Alto Health Care System, Palo Alto
- Stanford University Medical Center, Palo Alto
- and 2 more
RecruitingPhase 2/3
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06780670A Study of LY4257496 in Participants With Cancer (OMNIRAY)
- City of Hope, Duarte
- University of California, Los Angeles (UCLA), Santa Monica
- Stanford University Medical Center, Stanford
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601A Study of Xaluritamig Plus Abiraterone Versus Investigator's Choice in Participants With Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer
- City of Hope National Medical Center, Duarte
- City of Hope Orange County Lennar Foundation Cancer Center, Duarte
- Providence Saint Jude Medical Center, Fullerton
- and 3 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 22, 2026 · NCT07213674Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC
- Univ Cali Irvine ALS Neuromuscular, Orange
- Stanford University Medical Center, Palo Alto
- Sansum Clinic, Santa Barbara
RecruitingPhase 3
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277A Study of Metastases Free Survival With Saruparib vs Placebo Added to a Standard RT/ADT in Men With High-risk Prostate Cancer With a BRCA Mutation
- Research Site, La Jolla
- Research Site, La Jolla
- Research Site, Los Angeles
- and 2 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 18, 2026 · NCT06952803Carboplatin or Olaparib for BRcA Deficient Prostate Cancer
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT04038502A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
- City of Hope Comprehensive Cancer Center ( Site 0049), Duarte
- City of Hope Lennar Foundation Cancer Center ( Site 0059), Irvine
- Moores Cancer Center ( Site 0010), La Jolla
- and 5 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737First-Time-in-Human Study of GSK5471713 in Adults With mCRPC
- GSK Investigational Site, La Jolla
RecruitingPhase 1/2
Ages 18 and older · Men · Updated Sep 16, 2026 · NCT07332455A Study of [225Ac]Ac-AKY-2519 in Patients With Metastatic Castration-Resistant Prostate Cancer
- Hoag Memorial Hospital Presbyterian, Irvine
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT07581184Sacral Neuromodulation for Male Overactive Bladder (MOAB)
- USNC, Mountain View
- Tri Valley Urology, Murrieta
- University of California San Francisco, San Francisco
Recruiting
Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06511141Positron Emission Tomography Using 64Cu-SAR-bisPSMA in Participants With High-risk Prostate Cancer Prior to Radical Prostatectomy
- Urology Group of Southern California, Los Angeles
- Greater Los Angeles VA Medical Center, Los Angeles
- UC Irvine Health, Orange
- and 1 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 11, 2026 · NCT06056830Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer
- Kaiser Permanente-Deer Valley Medical Center, Antioch
- Tower Cancer Research Foundation, Beverly Hills
- Kaiser Permanente Dublin, Dublin
- and 34 more
RecruitingPhase 3
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer
- UCI Health Chao Family Comprehensive Cancer Center, Orange
- Investigational Site Number: 403, Palo Alto
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05997615Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer
- University of California, San Francisco, San Francisco
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05766371Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer
- Duarte Cancer Center, Duarte
- City of Hope Orange County Lennar Foundation Cancer Center, Irvine
Recruiting
Ages 18 and older · Men · Updated Sep 9, 2026 · NCT05804318A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors
- USC/Norris Comprehensive Cancer Center, Los Angeles
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06440005Longitudinal Advanced Prostate Cancer Cohort (LAPCC)
- Los Angeles General Medical Center, Los Angeles
- USC / Norris Comprehensive Cancer Center, Los Angeles
RecruitingObservational study
Ages 18 and older · Men · Updated Sep 8, 2026 · NCT06067295Study of JANX014 in Subjects With Metastatic Castration-Resistant Prostate Cancer
- UC San Diego Moores Cancer Center, La Jolla
RecruitingPhase 1
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07545811A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer
- Sharp HealthCare - Sharp Memorial Hospital, San Diego
RecruitingPhase 2
Ages 18 and older · Men · Updated Sep 3, 2026 · NCT07005154Prostate Active Surveillance Study
- Veterans Affairs San Francisco Health Care System, San Francisco
- University of California, San Francisco, San Francisco
- Stanford University, Stanford
RecruitingObservational study
Ages 21 and older · Men · Updated Sep 2, 2026 · NCT00756665From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.