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Ulcerative Colitis clinical trials in Chicago, IL

15 studies for Ulcerative Colitis are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

RecruitingPhase 2
  • Site 038, Chicago
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT07012395

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

RecruitingPhase 2
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06979336

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

RecruitingPhase 3
  • Rush University Medical Center, Chicago
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease

RecruitingPhase 2
  • Rush University Medical Center, Chicago
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07483073

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

RecruitingPhase 2
  • Northwestern University, Chicago
  • Rush University Medical Center, Chicago
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07415044

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

RecruitingPhase 2
  • Northwestern University, Chicago
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07186101

A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

RecruitingPhase 3
  • University of Chicago Medical Center /ID# 271588, Chicago
Ages 2 to 17 · All sexes · Updated Sep 22, 2026 · NCT07071519

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

RecruitingPhase 4
  • University of Chicago Medicine, Chicago
Ages 18 to 65 · All sexes · Updated Sep 21, 2026 · NCT06095128

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

RecruitingPhase 3
  • Rush University Medical Center - Site Number: 8400015, Chicago
Ages 16 to 80 · All sexes · Updated Aug 20, 2026 · NCT07184996

Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

Recruiting
  • University of Chicago Medicine, Chicago
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT05230173

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

RecruitingPhase 2
  • Northwestern University, Chicago
Ages 18 to 75 · All sexes · Updated Jul 30, 2026 · NCT06598943

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

RecruitingObservational study
  • Feinberg School of Medicine Northwestern University, Chicago
  • Rush University Medical Center, Chicago
Ages 18 to 64 · All sexes · Updated Jul 9, 2026 · NCT06398626

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

RecruitingPhase 2
  • University of Chicago Medical Center, Chicago
Ages 12 to 17 · All sexes · Updated Jul 8, 2026 · NCT05287126

Selenium Supplementation in Moderate-Severely Active Ulcerative Colitis Patients Treated With Advanced Therapies

RecruitingPhase 2
  • Northwestern University, Chicago
Ages 18 to 85 · All sexes · Updated May 22, 2026 · NCT07427017

STOP-UC: De-escalation of Therapy in Patients With Ulcerative Colitis With Histological Remission

Recruiting
  • University of Chicago, Chicago
Ages 18 to 75 · All sexes · Updated Apr 6, 2026 · NCT06693310

About Ulcerative Colitis

Ulcerative Colitis (UC) can cause long-lasting swelling and ulcers in the large intestine. It is a type of inflammatory bowel disease. Find out more.

More about Ulcerative Colitis on MedlinePlus

Ulcerative Colitis trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.