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Ulcerative Colitis clinical trials in Orlando, FL

23 studies for Ulcerative Colitis are looking for participants at sites in and around Orlando (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Trial to Investigate PALI-2108 Versus Placebo in Participants With Moderately to Severely Active Ulcerative Colitis

RecruitingPhase 2
  • Site US-026, Orlando
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT07845487

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

RecruitingPhase 2
  • Digestive And Liver Center Of Florida - Orlando /ID# 280924, Orlando
  • Clinical Research of Osceola /ID# 280593, Kissimmee · 16 mi away
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT07697456

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

RecruitingPhase 2
  • Site 007, Kissimmee · 16 mi away
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT07012395

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

RecruitingPhase 1/2Healthy volunteers welcome
  • Xencor Investigative Site, Kissimmee · 16 mi away
Ages 18 to 75 · All sexes · Updated Sep 29, 2026 · NCT06619990

A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics (PK) of RO7837195 in Participants With Moderately to Severely Active Ulcerative Colitis (UC)

RecruitingPhase 2
  • Clinical Research of Osceola, LLC, Kissimmee · 16 mi away
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06979336

A Study to Evaluate Efficacy and Safety of MK-8690 in Participants With Moderately to Severely Active Ulcerative Colitis (MK-8690-002)

RecruitingPhase 2
  • AdventHealth Orlando ( Site 1074), Orlando
Ages 18 to 75 · All sexes · Updated Sep 28, 2026 · NCT07463183

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

RecruitingPhase 3
  • Orlando Health, Orlando
  • Digestive and Liver Center of Florida, Orlando
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis

RecruitingPhase 2
  • AdventHealth Orlando, Orlando
  • Clinical Research of Osceola, Kissimmee · 16 mi away
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07415044

LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:

RecruitingPhase 2
  • Digestive and Liver Center of Florida, Orlando
  • Clinical Research of Osceola, Kissimmee · 16 mi away
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07186101

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

RecruitingPhase 4
  • Endoscopic Research Inc, Orlando
Ages 18 to 65 · All sexes · Updated Sep 21, 2026 · NCT06095128

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

RecruitingPhase 3
  • Clinical Research of Osceola - Site Number: 8400013, Kissimmee · 16 mi away
Ages 16 to 80 · All sexes · Updated Sep 15, 2026 · NCT07185009

A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

RecruitingPhase 4
  • Endoscopic Research, Inc., Orlando
  • Orlando Health-Orlando Regional Medical Center, Orlando
  • Digestive and Liver Center of Florida, P.A., Kissimmee · 16 mi away
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT06581328

Confirmatory Clinical Study in Active Ulcerative Colitis

RecruitingPhase 2
  • Orlando Gastroenterology, P.A., Orlando
Ages 16 and older · All sexes · Updated Sep 9, 2026 · NCT07296315

A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis

RecruitingPhase 2
  • Primary Care of Osceola, Kissimmee · 16 mi away
Ages 18 to 80 · All sexes · Updated Aug 21, 2026 · NCT06636656

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis

RecruitingPhase 3
  • Orlando Health, Inc. - Site Number: 8400084, Orlando
  • AdventHealth Orlando - Site Number: 8400070, Orlando
  • Clinical Research of Osceola - Site Number: 8400013, Kissimmee · 16 mi away
  • and 1 more
Ages 16 to 80 · All sexes · Updated Aug 20, 2026 · NCT07184996

Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

Recruiting
  • Advent Health, Orlando
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT05230173

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

RecruitingObservational study
  • AdventHealth, Orlando
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07237516

A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis

RecruitingPhase 2
  • Orlando Health Digestive Health Institute, Orlando
  • AdventHealth Orlando, Orlando
  • Novum Research, LLC, Clermont · 24 mi away
Ages 18 to 75 · All sexes · Updated Jul 30, 2026 · NCT06598943

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

RecruitingObservational study
  • Orlando Health/Digestive Health Institute, Orlando
  • Digestive and Liver Center of Florida Kissimmee, Kissimmee · 16 mi away
Ages 18 to 64 · All sexes · Updated Jul 9, 2026 · NCT06398626

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

RecruitingPhase 2
  • Arnold Palmer Hospital - Center for Digestive Health and Nutrition, Orlando
Ages 12 to 17 · All sexes · Updated Jul 8, 2026 · NCT05287126

A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis

RecruitingPhase 2
  • Investigational Site Number: 8400030, Kissimmee · 16 mi away
Ages 18 to 75 · All sexes · Updated Apr 23, 2026 · NCT06975722

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

RecruitingPhase 2
  • Mirador Therapeutics Selected Site, Orlando
Ages 18 to 80 · All sexes · Updated Mar 12, 2026 · NCT07113522

Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

Recruiting
  • Orlando Health, Orlando
Ages 18 to 85 · All sexes · Updated Jan 8, 2026 · NCT05987852

About Ulcerative Colitis

Ulcerative Colitis (UC) can cause long-lasting swelling and ulcers in the large intestine. It is a type of inflammatory bowel disease. Find out more.

More about Ulcerative Colitis on MedlinePlus

Ulcerative Colitis trials in other cities

Other studies in Orlando

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.