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ALS and Motor Neuron Disease clinical trials in Boston, MA

4 studies for ALS and Motor Neuron Disease are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis

RecruitingPhase 1
  • Massachusetts General Hospital, Healey & AMG Center for ALS, Boston
Ages 18 and older · All sexes · Updated Apr 14, 2026 · NCT06665165

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

RecruitingObservational study
  • Boston Children's Hospital, Boston
1 Month – 30 Years · All sexes · Updated Mar 18, 2026 · NCT05354622

Spastic Paraplegia - Centers of Excellence Research Network

RecruitingObservational study
  • Boston Children's Hospital, Boston
  • Massachusetts General Hospital, Boston
All ages · All sexes · Updated Mar 18, 2026 · NCT06553976

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

RecruitingObservational studyHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05137665

ALS and Motor Neuron Disease trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.