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Cardiovascular Disease clinical trials in St. Louis, MO
20 studies for Cardiovascular Disease are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
RecruitingPhase 3
- St. Louis Heart and Vascular, P.C., St Louis
- Sundance Clinical Research, LLC, St Louis
Product Surveillance Registry
RecruitingObservational study
- St Louis, St Louis
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
RecruitingPhase 3
- Clinical Trial Site, St Louis
- Clinical Trial Site, St Louis
Zenith® Fenestrated+ Clinical Study
Recruiting
- Barnes Jewish Hospital, St Louis
Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.
Recruiting
- Barnes-Jewish Hospital, St Louis
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
Recruiting
- WashU Medicine, St Louis
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
RecruitingPhase 3
- Washington Univ School Of Medicine, St Louis
- Mercy Hospital St Louis, St Louis
PET Imaging of Natriuretic Peptide Receptor C (NPR-C) in Carotid Atherosclerosis With 64Cu-NODAGA-CANF (Volunteer - Dosimetry Study)
RecruitingEarly phase 1Healthy volunteers welcome
- Washington University School of Medicine, St Louis
Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults
RecruitingPhase 4Healthy volunteers welcome
- St. Louis VA Medical Center, St Louis
- Washington University in St. Louis, St Louis
A Study About How Blood Cell Growth Patterns Relate to Heart Health After Treatment for Hodgkin Lymphoma
RecruitingObservational study
- Washington University School of Medicine, St Louis
A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event
RecruitingPhase 3
- Research Site, St Louis
- Research Site, St Louis
- Research Site, Hazelwood · 14 mi away
- and 1 more
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
RecruitingPhase 3
- Washington University, St Louis
- Sisters of Saint Mary Health Heart and Vascular Care, Bridgeton · 15 mi away
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
RecruitingPhase 3
- Washington Univ School Of Medicine, St Louis
Evaluation of a Novel Technology to Support Tailored Health Behavior Counseling in Rural Primary Care Clinics
Recruiting
- Washington University in St. Louis, St Louis
Adapting and Testing a Novel Digital Health Tool (PREVENT) to Improve Health Behavior Counseling and Cardiovascular Health in Rural Primary Care Clinics
Recruiting
- Washington University in St. Louis, St Louis
Aging, Geriatric Syndromes and Clonal Hematopoiesis
RecruitingObservational studyHealthy volunteers welcome
- Washington University School of Medicine, St Louis
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
Recruiting
- St. Louis Heart and Vascular, St Louis
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
RecruitingPhase 3
- Washington University, St Louis
CANF-Comb-II PET-MR in Atherosclerosis Multisite
RecruitingObservational study
- Washington University in St. Louis, St Louis
PARTNER 3 Trial - Aortic Valve-in-Valve
Recruiting
- Washington University/ Barnes-Jewish Hospital, St Louis
Cardiovascular Disease trials in other cities
- Boston, MA37 studies
- New York City, NY33 studies
- Washington, DC29 studies
- Houston, TX24 studies
- Dallas, TX23 studies
- Atlanta, GA22 studies
- Cleveland, OH22 studies
- Chicago, IL21 studies
- Philadelphia, PA21 studies
- Pittsburgh, PA20 studies
- San Francisco, CA18 studies
- Nashville, TN18 studies
Other studies in St. Louis
- Non-Small Cell Lung Cancer73 studies
- Breast Cancer64 studies
- Metastatic Cancer54 studies
- Colorectal Cancer50 studies
- Prostate Cancer46 studies
- Cancer (all types)46 studies
- Lung Cancer39 studies
- Ovarian Cancer38 studies
- Pancreatic Cancer33 studies
- Endometrial Cancer29 studies
- Head and Neck Squamous Cell Carcinoma28 studies
- Heart Failure26 studies
From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.