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Head and Neck Cancer clinical trials in Rochester, MN

8 studies for Head and Neck Cancer are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

RecruitingPhase 2/3
  • Site #0146, Rochester
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06788990

Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States Population

RecruitingPhase 2
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06997068

Continuous Monitoring of Microvascular Anastomoses: An Observational Trial

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07823283

First in Human Study of TUB-030 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06657222

Lead-212 PSV359 Therapy for Patients With Solid Tumors

RecruitingPhase 1/2
  • Mayo Clinic in Rochester, Minnesota, Rochester
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756

Oropharynx (OPX) Biomarker Trial

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT06356272

An Imaging Agent (Pafolacianine) for Identifying Lesions in Pediatric Patients With Primary or Metastatic Solid Tumors

RecruitingPhase 3
  • Mayo Clinic in Rochester, Rochester
6 Months – 17 Years · All sexes · Updated Apr 1, 2026 · NCT06915727

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic, Rochester
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

About Head and Neck Cancer

Head and neck cancer includes cancers of the mouth, nose, sinuses, salivary glands, throat, and lymph nodes. Read the different symptoms of each type.

More about Head and Neck Cancer on MedlinePlus

Head and Neck Cancer trials in other cities

Other studies in Rochester

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.