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Mild Cognitive Impairment clinical trials in Durham, NC

9 studies for Mild Cognitive Impairment are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

RecruitingObservational study
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT04916210

ADRC Clinical Cohort (Alzheimer's Disease)

RecruitingObservational studyHealthy volunteers welcome
  • Duke University, Durham
Ages 25 to 80 · All sexes · Updated Sep 3, 2026 · NCT06703541

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • PREVENTABLE Tele-Site, Durham
  • Duke University, Durham
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease

RecruitingPhase 1
  • Duke University, Durham
Ages 50 to 85 · All sexes · Updated Aug 24, 2026 · NCT06297590

Neuromodulation of Memory in Aging

RecruitingHealthy volunteers welcome
  • Duke University Hospital, Durham
Ages 18 to 75 · All sexes · Updated Aug 11, 2026 · NCT05460468

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

RecruitingPhase 2
  • Duke University Medical Center, Durham
Ages 55 to 89 · All sexes · Updated Jul 28, 2026 · NCT06601933

Memantine and Exercise to Improve Cognitive Function and Modulate Biological Pathways of Cognitive Decline During Chemotherapy in Breast Cancer

RecruitingPhase 2
  • Lineberger Comprehensive Cancer Center at University of North Carolina, Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · Women · Updated May 6, 2026 · NCT06727773

Cancer and Mild Cognitive Impairment Dyadic Intervention

Recruiting
  • Duke University, Durham
Ages 18 to 100 · All sexes · Updated Feb 10, 2026 · NCT05144516

Retinal Imaging in Neurodegenerative Disease

RecruitingObservational studyHealthy volunteers welcome
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Feb 4, 2026 · NCT03233646

About Mild Cognitive Impairment

In mild cognitive impairment (MCI), you have more memory and thinking problems than others your age, but they don't interfere with your everyday life.

More about Mild Cognitive Impairment on MedlinePlus

Mild Cognitive Impairment trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.