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Myelodysplastic Syndromes clinical trials in Chicago, IL

13 studies for Myelodysplastic Syndromes are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

RecruitingPhase 2
  • Northwestern University, Chicago
  • Swedish Covenant Hospital, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06577441

Testing the Anti-cancer Drug, Cirtuvivint, and Its Combination With ASTX727 to Improve Outcomes in Patients With Acute Myeloid Leukemia and Myelodysplastic Syndromes

RecruitingPhase 1
  • University of Chicago Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06484062

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

RecruitingPhase 2
  • Northwestern University, Chicago
  • University of Illinois, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05564390

Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

RecruitingPhase 3
  • University of Chicago, Duchossois Center for Advanced Medicine (DCAM), Chicago
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06465953

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

RecruitingPhase 1/2
  • Lurie Children's Hospital-Chicago, Chicago
  • University of Illinois, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
Up to age 22 · All sexes · Updated Aug 25, 2026 · NCT04726241

Mosaic Trial for Stem Cell Transplant Recipients

Recruiting
  • Northwestern University Feinberg School of Medicine, Chicago
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT06960993

A Study of CTX-712 in Relapsed/Refractory Acute Myeloid Leukemia and Higher Risk Myelodysplastic Syndromes

RecruitingPhase 1/2
  • Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT05732103

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

RecruitingPhase 1/2
  • Northwestern, Chicago
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

Venetoclax Basket Trial for High Risk Hematologic Malignancies

RecruitingPhase 1
  • Ann & Robert H Lurie Children's Hospital of Chicago, Chicago
Ages 1 to 40 · All sexes · Updated Mar 12, 2026 · NCT05292664

Leukemia and Lymphoma Society (LLS) Services Impact on Outcomes and Care

Recruiting
  • University of Chicago Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Feb 20, 2026 · NCT05745285

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chicago
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

RecruitingPhase 1
  • Northwestern Medicine - Northwestern Memorial Hospital Galter Pavilion, Chicago
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT06501196

About Myelodysplastic Syndromes

Myelodysplastic Syndromes (MDS) are rare. They are sometimes found during a routine blood test. Learn symptoms, risk factors, and treatment options.

More about Myelodysplastic Syndromes on MedlinePlus

Myelodysplastic Syndromes trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.