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Rectal Cancer clinical trials in Rochester, MN

8 studies for Rectal Cancer are looking for participants at sites in and around Rochester (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)

RecruitingPhase 3
  • Mayo Clinic in Rochester, Minnesota ( Site 0091), Rochester
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06997497

PRE-ISPY Phase I/II Oncology Platform Program

RecruitingPhase 1/2
  • Mayo Clinic Comprehensive Cancer Center, Rochester
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05868226

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • Mayo Clinic (Rochester), Rochester
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

Recruiting
  • Mayo Clinic in Rochester, Rochester
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673

Post-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal Resections

Recruiting
  • Mayo Clinic, Rochester
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07351071

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • Mayo Clinic Rochester, Rochester
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Contrast-Enhanced Photon-Counting Detector CT (PCD-CT) for the Local Staging of Rectal Cancer

RecruitingObservational study
  • Mayo Clinic in Rochester, Rochester
Ages 18 to 99 · All sexes · Updated Apr 22, 2026 · NCT06965166

Rectal Cancer trials in other cities

Other studies in Rochester

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.