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Alzheimer's Disease clinical trials in New York City, NY

21 studies for Alzheimer's Disease are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis

RecruitingPhase 2
  • Clinical Site, New York
Ages 55 to 90 · All sexes · Updated Sep 30, 2026 · NCT06887192

Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease

RecruitingPhase 2
  • Adams Clinic Harlem, New York
Ages 55 to 80 · All sexes · Updated Sep 21, 2026 · NCT06847321

Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies

RecruitingPhase 3
  • Weill Cornell Medical College, New York
  • Adams Clinical Harlem, New York
Ages 50 to 90 · All sexes · Updated Sep 21, 2026 · NCT07177352

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease

RecruitingPhase 3
  • NYU Langone Health, New York
Ages 60 to 85 · All sexes · Updated Aug 20, 2026 · NCT06976216

Early Age-Related Hearing Loss Investigation (EARHLI)

Recruiting
  • Columbia University Medical Center, New York
Ages 55 to 75 · All sexes · Updated Aug 12, 2026 · NCT06174038

The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study

Recruiting
  • New York University, New York
  • Mount Sinai, New York
Ages 55 to 85 · All sexes · Updated Aug 6, 2026 · NCT05988385

Autoimmune Features of Neurodegenerative Disorders

RecruitingObservational studyHealthy volunteers welcome
  • Columbia University Medical Center, New York
Ages 55 to 90 · All sexes · Updated Aug 4, 2026 · NCT04239079

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • New York University (NYU) School of Medicine - Langone Medical Center, New York
  • Mount Sinai Hospital, New York
  • Columbia University Medical Center, New York
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

RecruitingPhase 2/3Healthy volunteers welcome
  • New York University Medical Center, New York
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT05552157

A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

RecruitingPhase 2/3Healthy volunteers welcome
  • New York University Medical Center, New York
Ages 18 and older · All sexes · Updated Jul 27, 2026 · NCT06647498

Designing Care Management for Hospice Transitions for Persons Living With Advanced Dementia

RecruitingHealthy volunteers welcome
  • NYU Rory Meyers College of Nursing and VNS Health, New York
Ages 18 and older · All sexes · Updated Jul 8, 2026 · NCT07182357

Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease

RecruitingPhase 2Healthy volunteers welcome
  • Columbia University Irving Medical Center, New York
Ages 50 and older · All sexes · Updated Jul 6, 2026 · NCT04576793

Safety Assessment of Leronlimab and Its Effect on Brain Inflammation in Alzheimer's Disease

RecruitingPhase 2
  • Weill Cornell Medicine Brain Health Imaging Institute, New York
Ages 50 and older · All sexes · Updated May 22, 2026 · NCT07553338

Late Onset Alzheimer's Disease

RecruitingObservational studyHealthy volunteers welcome
  • Columbia University Irving Medical Center, New York
Ages 55 and older · All sexes · Updated May 18, 2026 · NCT05010603

Aβ Dynamics in LLMD

RecruitingPhase 4
  • NYU Langone Health, New York
Ages 60 and older · All sexes · Updated May 6, 2026 · NCT05004987

Genetic Studies of Early-onset Dementia

RecruitingObservational studyHealthy volunteers welcome
  • Columbia University Irving Medical Center, New York
Ages 35 and older · All sexes · Updated Apr 29, 2026 · NCT04906863

Dementia Caregivers' Link to Assistance and Resources

RecruitingHealthy volunteers welcome
  • VNS Health Home Care, New York
All ages · All sexes · Updated Mar 13, 2026 · NCT06860035

Evaluating the Efficacy of the Pain Identification and Communication Toolkit

Recruiting
  • Weill Cornell Medicine, New York
Ages 21 and older · All sexes · Updated Feb 12, 2026 · NCT06168604

Innate Immunity Stimulation Via TLR9 in Early AD

RecruitingPhase 1
  • NYU Langone Health, New York
Ages 60 to 85 · All sexes · Updated Jan 7, 2026 · NCT05606341

NYSCF Scientific Discovery Biobank

RecruitingObservational study
  • New York Stem Cell Foundation Research Institute, New York
30 Days · All sexes · Updated Mar 3, 2025 · NCT06203106

Triage Survey for Neurology Research Eligibility

RecruitingObservational studyHealthy volunteers welcome
  • Berman Clinical, New York
Ages 18 and older · All sexes · Updated Oct 27, 2023 · NCT06104852

About Alzheimer's Disease

Alzheimer's disease is a brain disorder that slowly destroys memory and thinking skills. It's the most common cause of dementia among older adults.

More about Alzheimer's Disease on MedlinePlus

Alzheimer's Disease trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.