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Breast Cancer clinical trials in Sacramento, CA

20 studies for Breast Cancer are looking for participants at sites in and around Sacramento (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer

RecruitingPhase 3
  • University of California, Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06982521

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

RecruitingPhase 3
  • Sutter Inst Medical Research, Sacramento
  • School Of Medicine, Sacramento
Ages 18 to 100 · All sexes · Updated Oct 2, 2026 · NCT05827081

Distance-Based Exercise to Preserve Function and Prevent Disability

Recruiting
  • Kaiser Permanente-South Sacramento, Sacramento
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07059884

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mercy Cancer Center - Sacramento, Sacramento
  • Woodland Memorial Hospital, Woodland · 16 mi away
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

RecruitingHealthy volunteers welcome
  • University of California Davis, Sacramento
Ages 30 to 74 · Women · Updated Sep 21, 2026 · NCT02620852

ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer

RecruitingPhase 3
  • University Of California Davis Health System, Sacramento
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07173751

ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE) - iSono Health

RecruitingObservational study
  • UC Davis, Sacramento
Ages 18 to 94 · Women · Updated Sep 17, 2026 · NCT07505797

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

RecruitingPhase 3
  • Dignity Health dba Health Research Institute, Sacramento
  • Sutter Institute for Medical Research, Sacramento
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • Kaiser Permanente Downtown Commons, Sacramento
  • Mercy Cancer Center - Sacramento, Sacramento
  • Sutter Medical Center Sacramento, Sacramento
  • and 5 more
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

A Multi-Modality Surveillance Program for Women at High Risk for Breast Cancer

RecruitingHealthy volunteers welcome
  • University of California, Davis, Sacramento
Ages 25 and older · Women · Updated Sep 1, 2026 · NCT03729115

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Kaiser Permanente Downtown Commons, Sacramento
  • Kaiser Permanente-South Sacramento, Sacramento
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Locally ablatiVe therApy in oLigO-pRogressive sOlid tUmorS (VALOROUS)

Recruiting
  • University of California, Davis, Sacramento
Ages 18 and older · All sexes · Updated Jul 8, 2026 · NCT06103669

UHFUS Characterization of Normal Lymphatic Anatomy

Recruiting
  • University of California Davis Health, Sacramento
Ages 18 and older · All sexes · Updated Jul 1, 2026 · NCT07677839

I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

RecruitingPhase 2
  • University of California - Davis, Comprehensive Cancer Center, Davis · 14 mi away
Ages 18 and older · All sexes · Updated May 6, 2026 · NCT01042379

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Kaiser Permanente Downtown Commons, Sacramento
  • Mercy Cancer Center - Sacramento, Sacramento
  • Sutter Medical Center Sacramento, Sacramento
  • and 4 more
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

A Study of DB-1310 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of California, Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Apr 6, 2026 · NCT05785741

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Kaiser Permanente Downtown Commons, Sacramento
  • Mercy Cancer Center - Sacramento, Sacramento
  • Kaiser Permanente-South Sacramento, Sacramento
  • and 1 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

Tart Cherry Juice as a Dietary Supplement for the Prevention of Paclitaxel-Induced Neuropathy

RecruitingPhase 2
  • University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Mar 4, 2026 · NCT06268665

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Sacramento

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.