🔎 Trials Near Me

Home › Liver Cancer (Hepatocellular Carcinoma) › Massachusetts › Boston

Liver Cancer (Hepatocellular Carcinoma) clinical trials in Boston, MA

18 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #7, Boston
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

National Liver Cancer Screening Trial

RecruitingPhase 4
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Sep 25, 2026 · NCT06084234

Safety and Preliminary Anti-Tumor Activity of TYRA-430 in Advanced Hepatocellular Carcinoma and Other Solid Tumors With Activating FGF/FGFR Pathway Aberrations

RecruitingPhase 1
  • Mass General Cancer Center, Boston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06915753

Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure

RecruitingPhase 2
  • Massachusetts General Hospital, Boston
Ages 18 to 100 · All sexes · Updated Sep 23, 2026 · NCT07219459

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

RecruitingObservational study
  • Mass General Brigham, Boston
Ages 22 and older · All sexes · Updated Sep 11, 2026 · NCT06486454

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Dana-Farber Cancer Institute, Boston
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Massachusetts General Hospital, Boston
  • Dana Farber Cancer Institute, Boston
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial

RecruitingPhase 3
  • Massachusetts General Hospital Cancer Center, Boston
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07166406

First in Human Study to Evaluate AZD9793 in Participants With Advanced or Metastatic Solid Tumours

RecruitingPhase 1/2
  • Research Site, Boston
Ages 18 and older · All sexes · Updated Aug 13, 2026 · NCT06795022

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • Tufts Medical Center, Boston
  • Massachusetts General Hospital, Boston
  • Dana-Farber Cancer Institute, Boston
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

RecruitingPhase 1/2
  • Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston
Ages 1 to 21 · All sexes · Updated Jul 6, 2026 · NCT04634357

Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

Recruiting
  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston
Ages 18 to 75 · All sexes · Updated Jun 17, 2026 · NCT05486572

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

RecruitingPhase 1
  • Mass General Brigham Cancer Institute, Boston
  • Dana Farber Cancer Institute, Boston
Ages 16 and older · All sexes · Updated Jun 2, 2026 · NCT07197554

Computer Guided Microwave Liver Ablation

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 to 90 · All sexes · Updated May 11, 2026 · NCT07226869

Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma

RecruitingPhase 2
  • Children's Hospital Boston, Boston
  • Dana Farber Cancer Institute, Boston
Ages 0 to 30 · All sexes · Updated Feb 24, 2026 · NCT04134559

Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

RecruitingPhase 4
  • Massachussets General Hospital, Boston
Ages 18 to 64 · All sexes · Updated Jan 22, 2026 · NCT04373564

Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis

RecruitingObservational study
  • Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown · 1 mi away
Ages 18 to 99 · All sexes · Updated Sep 26, 2025 · NCT06265272

Psychoeducational Intervention for Patients With Hepatocellular Carcinoma

Recruiting
  • Massachusetts General Hospital, Boston
Ages 18 and older · All sexes · Updated Aug 29, 2025 · NCT06541990

Liver Cancer (Hepatocellular Carcinoma) trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.