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Liver Cancer (Hepatocellular Carcinoma) clinical trials in Cleveland, OH
18 studies for Liver Cancer (Hepatocellular Carcinoma) are looking for participants at sites in and around Cleveland (within about 30 miles). Open a study to see who can join and how to contact the study team.
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The Vanguard Study: Testing a New Way to Screen for Cancer
RecruitingHealthy volunteers welcome
- Louis Stokes Cleveland VA Medical Center, Cleveland
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
RecruitingPhase 1
- Exelixis Clinical Site #10, Cleveland
Symbiotic-GI-13: A Study to Learn About Study Medicine Called PF-08634404 as a Single Treatment and Combination Treatment in Adult Participants With a Liver Cancer Called Hepatocellular Carcinoma, That is Too Advanced to be Removed by Surgery and May Have Spread to Other Parts of the Body.
RecruitingPhase 1/2
- University Hospitals Cleveland Medical Center, Cleveland
National Liver Cancer Screening Trial
RecruitingPhase 4
- The Cleveland Clinic, Cleveland
A Study Evaluating a New Radiation Treatment Workflow (NGDS)
Recruiting
- University Hospital Cleveland Medical Center, Cleveland
Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)
RecruitingObservational study
- Cleveland Clinic Foundation, Cleveland
FOG-001 in Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 1/2
- University Hospitals Cleveland Medical Center, Seidman Cancer Center, Cleveland
- Cleveland Clinic, Cleveland
Testing Immunotherapy With or Without Stereotactic Body Radiation Therapy in Patients With Advanced Liver Cancer, HELIO-RT Trial
RecruitingPhase 3
- Case Western Reserve University, Cleveland
- UHHS-Chagrin Highlands Medical Center, Beachwood · 10 mi away
- UH Seidman Cancer Center at Lake Health Mentor Campus, Mentor · 22 mi away
A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors
RecruitingPhase 1
- University Hospitals Cleveland Medical Center, Cleveland
DRAGON Registry - International Multicenter Registry and Medical Image Bank for Patients With Primarily Unresectable Liver Cancer or Liver Metastases That Underwent Combined Portal and Hepatic Vein Embolization (PVE/HVE) to Increase Future Liver Remnant Before Resection.
RecruitingObservational study
- Cleveland Clinic, Cleveland
A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma
RecruitingPhase 1
- Clinical Trial Site, Cleveland
Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
Recruiting
- Louis Stokes VA Medical Center, Cleveland, OH, Cleveland
68Ga-PSMA-11 PET-directed Radioligand Therapy in Metastatic Hepatocellular Carcinoma (HCC)
RecruitingPhase 2
- Case Comprehensive Cancer Center, University Hospitals Cleveland Medical Center, Seidman Cancer Center, Cleveland
A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma
RecruitingPhase 1/2
- Cleveland Clinic Lerner College of Medicine, Cleveland
HOPE Against Cancer Recurrence in HCC
RecruitingPhase 4
- Cleveland Clinic, Cleveland
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Mayfield Heights · 12 mi away
The Dragon PLC Trial (DRAGON-PLC)
Recruiting
- Cleveland Clinic, Cleveland
A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)
RecruitingPhase 1/2
- Cleveland Clinic, Cleveland
Liver Cancer (Hepatocellular Carcinoma) trials in other cities
- Houston, TX31 studies
- New York City, NY24 studies
- Dallas, TX19 studies
- Los Angeles, CA19 studies
- Boston, MA18 studies
- Philadelphia, PA16 studies
- Chicago, IL16 studies
- Pittsburgh, PA15 studies
- San Francisco, CA14 studies
- Orange, CA14 studies
- Jacksonville, FL14 studies
- San Antonio, TX13 studies
Other studies in Cleveland
- Non-Small Cell Lung Cancer43 studies
- Cancer (all types)36 studies
- Breast Cancer35 studies
- Prostate Cancer34 studies
- Heart Failure33 studies
- Ovarian Cancer30 studies
- Metastatic Cancer30 studies
- Lung Cancer26 studies
- Colorectal Cancer24 studies
- Cardiovascular Disease22 studies
- Endometrial Cancer20 studies
- Acute Myeloid Leukemia20 studies
From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.