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Pancreatic Cancer clinical trials in Philadelphia, PA

26 studies for Pancreatic Cancer are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Atebimetinib + GnP as a First Line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

RecruitingPhase 3
  • Thomas Jefferson University, Philadelphia
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07562152

A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors

RecruitingPhase 1
  • Sidney Kimmel Comprehensive Cancer Center Thomas Jefferson University, Philadelphia
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277413

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Philadelphia
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 3
  • University of Pennsylvania, Abramson Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07252232

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

RecruitingPhase 3
  • Investigative Site US008, Philadelphia
  • Investigative Site US043, Philadelphia
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07522073

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • Hospital of the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

Prehabilitation in High-risk Oncologic Surgery

Recruiting
  • Fox Chase Cancer Center - Philadelphia, Philadelphia
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07638410

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 2
  • Thomas Jefferson University, Sidney Kimmel Comprensive Cancer Center, Clinical Trials Office, Philadelphia
Ages 18 and older · All sexes · Updated Sep 18, 2026 · NCT07450859

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

RecruitingObservational study
  • Children's Hospital of Philadelphia, Philadelphia
Up to age 17 · All sexes · Updated Sep 11, 2026 · NCT06651580

Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

RecruitingObservational study
  • University of Pennsylvania/Abramson Cancer Center, Philadelphia
  • Thomas Jefferson University Hospital, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
  • and 5 more
Ages 50 to 75 · All sexes · Updated Sep 4, 2026 · NCT04239573

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

RecruitingPhase 3
  • Thomas Jefferson University Hospital, Philadelphia
  • Jefferson Torresdale Hospital, Philadelphia
  • Christiana Care Health System-Concord Health Center, Chadds Ford · 23 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06958328

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Investigative Site #109, Philadelphia
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06545942

Pancreatic Cancer Early Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • University of Pennsylvania, Philadelphia
  • Fox Chase Cancer Center, Philadelphia
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • Sidney Kimmel Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

Studying Chemotherapy With or Without Panitumumab for Unresectable, Locally Advanced, or Metastatic Pancreatic Cancer Without KRAS Mutations

RecruitingPhase 3
  • Christiana Care Health System-Concord Health Center, Chadds Ford · 23 mi away
  • Christiana Care Health System-Wilmington Hospital, Wilmington · 25 mi away
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06998940

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • Univ of Pennsylvania, Abramson Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

Collection of Circulating Biomarkers in Pancreatic Cancer

RecruitingObservational study
  • Abramson Cancer Center at University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT05743049

Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

RecruitingPhase 2
  • Sidney Kimmel Cancer Center, Thomas Jefferson University Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Apr 3, 2026 · NCT06850623

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

RecruitingPhase 1/2
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06244771

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

A Phase II Nationwide, Fully Decentralized, Telemedicine Study of Pemigatinib in Adult Patients With Advanced or Metastatic Pancreatic Cancer With FGFR Genetic Alterations

RecruitingPhase 2
  • Ohio State University-Telemedicine, Philadelphia
  • Ohio State University-Telemedicine, Wilmington · 25 mi away
Ages 18 and older · All sexes · Updated Feb 17, 2026 · NCT06906562

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

RecruitingObservational study
  • Abramson Cancer Center of the University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT02478892

FTT PET/CT in Pancreatic Neuroendocrine Tumors

RecruitingPhase 1
  • University of Pennsylvania, Perelman Center for Advanced Medicine, Philadelphia
Ages 18 and older · All sexes · Updated Feb 2, 2026 · NCT07114939

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • Christiana Care Health System-Wilmington Hospital, Wilmington · 25 mi away
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Philadelphia
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

The Cancer of the Pancreas Screening-5 CAPS5)Study

RecruitingPhase 3
  • University of Pennsylvania, Philadelphia
Ages 18 and older · All sexes · Updated Oct 9, 2025 · NCT02000089

About Pancreatic Cancer

The pancreas is a gland behind your stomach that produces insulin. Pancreatic cancer is hard to catch early. Find out about risk factors and symptoms.

More about Pancreatic Cancer on MedlinePlus

Pancreatic Cancer trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.