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Healthy volunteer studies in Jacksonville, FL

58 studies at sites in and around Jacksonville accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

RecruitingHealthy volunteers welcome
  • UF Health Jacksonville, Jacksonville
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418

Pivotal Trial for an Automated AI-based System for Detection of Diabetic Retinopathy

RecruitingObservational studyHealthy volunteers welcome
  • Rovia Site Network, Jacksonville
Ages 22 and older · All sexes · Updated Sep 28, 2026 · NCT07844317

Dominantly Inherited Alzheimer Network (DIAN)

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic Jacksonville, Jacksonville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT00869817

A Study to Assess the Safety, Tolerability, and Immunogenicity of 3 Lots of a Multivalent Pneumococcal Conjugate Vaccine Administered to Adults

RecruitingPhase 3Healthy volunteers welcome
  • East Coast Institute for Research, LLC, Jacksonville
Ages 18 to 49 · All sexes · Updated Sep 23, 2026 · NCT07794748

American Lung Association (ALA) Lung Health Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Nemours Children's Jacksonville, Jacksonville
  • University of Florida, Jacksonville, Jacksonville
Ages 25 to 35 · All sexes · Updated Sep 23, 2026 · NCT04543461

Supporting Just-In-Time Consent for Prenatal Screening: The INFORM Study

RecruitingHealthy volunteers welcome
  • University of Florida Health, Jacksonville
Ages 18 and older · Women · Updated Sep 22, 2026 · NCT07557303

Identifying Patterns in the Breath of Individuals With Breast Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic Breast Clinic, Jacksonville
Ages 40 to 74 · Women · Updated Sep 18, 2026 · NCT06512350

Comparison of Ultrasound and Anatomic Landmark Techniques of the Ulnar and Posterior Tibial Nerves

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic, Jacksonville
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07515911

Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

RecruitingPhase 1/2Healthy volunteers welcome
  • Xencor Investigative Site, Jacksonville
Ages 18 to 75 · All sexes · Updated Sep 16, 2026 · NCT06619990

A Study Of Augmented Reality Real-Time Guidance With In-situ Feedback

RecruitingHealthy volunteers welcome
  • Mayo Clinic, Jacksonville
Ages 18 to 90 · All sexes · Updated Sep 16, 2026 · NCT07822425

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

RecruitingPhase 3Healthy volunteers welcome
  • ACCOMPLISH-2 Research Site, Jacksonville
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

Observational, Non-Interventional Study Supporting Validation of eVO2peak Using Results in Patients Receiving Standard of Care Cardiopulmonary Exercise Tests (CPET)

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic Florida, Jacksonville
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT05678530

A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older

RecruitingPhase 3Healthy volunteers welcome
  • Clinical Neuroscience Solutions, LLC, Jacksonville
Ages 65 and older · All sexes · Updated Sep 9, 2026 · NCT07282665

Community Enhanced Virtual Informed Consent

RecruitingHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07805083

Quality of End-of-Life Care for Children With Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Nemours Children's Clinic-Jacksonville, Jacksonville
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07412002

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • University of Florida, Jacksonville
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Integrating Molecular Pathology, Radiology, and Genetics to Improve Breast Cancer Risk

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 to 100 · Women · Updated Aug 27, 2026 · NCT07207564

Studies in Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Motor Neuron Disorders

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic Florida, Jacksonville
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT05474235

Safety and Pharmacokinetics Study of PGT121.414.LS Alone and in Combination With VRC07-523LS in Infants Exposed to HIV-1

RecruitingPhase 1Healthy volunteers welcome
  • Site 5051, University of Florida Jacksonville, Jacksonville
72 Hours · All sexes · Updated Aug 25, 2026 · NCT06517693

PREVENT ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic, Jacksonville
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06581861

ASSESS ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic, Jacksonville
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06578195

Low Dose Aspirin for the Prevention of Postpartum Related Breast Cancer

RecruitingPhase 2Healthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 to 45 · Women · Updated Aug 20, 2026 · NCT05557877

The Effect of Tirzepatide on Menopausal Vasomotor Symptoms and Biological Aging in Post-menopausal Women With Obesity

RecruitingPhase 4Healthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 46 to 60 · Women · Updated Aug 18, 2026 · NCT07218445

Ultrasound With Subharmonic Imaging and Subharmonic Aided Pressure Estimation (SHAPE) to Identify Portal Hypertension

RecruitingHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT06797193

A Virtual Community Health Educator for Increasing Clinical Trial Referrals Among Cancer Patients and Their Caregivers

RecruitingHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT07126496

Retina is a Marker for Cerebrovascular Heath

RecruitingPhase 1/2Healthy volunteers welcome
  • Mayo Clinic Florida, Jacksonville
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT04753970

Blinatumomab Consolidation in Real World

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic Cancer Center, Jacksonville
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07117136

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic Florida, Jacksonville
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684

Pancreatic Cancer Early Detection Consortium

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic Jacksonville, Jacksonville
Ages 18 to 90 · All sexes · Updated Jul 22, 2026 · NCT04970056

Deep Functional Phenotyping of the ALA Lung Health Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Nemours Children's Jacksonville, Jacksonville
Ages 25 to 35 · All sexes · Updated Jul 17, 2026 · NCT06177717

Evaluation of a Novel Auto Segmentation Algorithm for Normal Structure Delineation in Radiation Treatment Planning

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
All ages · All sexes · Updated Jul 8, 2026 · NCT06200116

Trial of Precision Medicine in Emergency Departments

RecruitingHealthy volunteers welcome
  • UF Health Jacksonville Downtown Emergency Department, Jacksonville
  • UF Health Jacksonville North Emergency Department, Jacksonville
Ages 40 and older · All sexes · Updated Jun 10, 2026 · NCT06448091

Ex Vivo Expansion (ACT-X)

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · All sexes · Updated Jun 9, 2026 · NCT07137312

Enfortumab Vedotin for the Treatment of Patients With Metastatic or Unresectable Squamous Cell Carcinoma of the Penis

RecruitingPhase 2Healthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · Men · Updated Jun 8, 2026 · NCT06104618

Smart Symptom Tracking ALEX Application for Tracking and Monitoring Gastrointestinal Health, Smart Horizons Pilot Trial

RecruitingHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 to 44 · All sexes · Updated Jun 5, 2026 · NCT07618273

Diaphragmatic Breathing for the Treatment of Bloating and Distension

RecruitingHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT06596759

Physical and Cognitive Aging Study in Older Adults

RecruitingObservational studyHealthy volunteers welcome
  • University of Florida, College of Medicine-Jacksonville, Jacksonville
Ages 55 to 85 · All sexes · Updated Jun 4, 2026 · NCT06726616

A Multilevel Approach to Connecting Underrepresented Populations to Clinical Trials

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 to 100 · All sexes · Updated May 8, 2026 · NCT05655494

Multi-Cancer Detection Observational Cohort Study

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 21 and older · All sexes · Updated Apr 6, 2026 · NCT06962995

Head-Cancelled Virtual Reality for Ocular Cranial Nerve Palsies

RecruitingHealthy volunteers welcome
  • Brooks Rehabilitation Hospital, Jacksonville
Ages 18 and older · All sexes · Updated Apr 6, 2026 · NCT06417216

Understanding Practices of Lactation and Infant Feeding Together With Women With HIV in the United States

RecruitingObservational studyHealthy volunteers welcome
  • University of Florida (5051), Jacksonville
All ages · All sexes · Updated Mar 27, 2026 · NCT07293559

Identification and Differentiation of Thyroid Nodules by Acoustic Imaging and Viscoelastic Parameters

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 8 and older · All sexes · Updated Mar 27, 2026 · NCT06207188

Reduced Immunosuppression in Older Renal Transplant Recipients With Trugraf®/TRAC Monitoring (RIOT Trial): A Prospective, Randomized, Multicenter Trial.

RecruitingPhase 4Healthy volunteers welcome
  • Mayo Clinic, Jacksonville
Ages 55 and older · All sexes · Updated Mar 20, 2026 · NCT06568549

Tailoring Bleeding Reduction Approaches in Patients Undergoing PCI

RecruitingPhase 4Healthy volunteers welcome
  • University of Florida, Jacksonville
Ages 18 and older · All sexes · Updated Mar 9, 2026 · NCT05681702

Potential Benefits of Parent Child Interaction Therapy (PCIT)

RecruitingObservational studyHealthy volunteers welcome
  • UF Health Psychiatry San Jose, Jacksonville
Ages 18 to 89 · All sexes · Updated Feb 12, 2026 · NCT06827951

Virtual Reality for Non-cardiac Chest Pain

RecruitingHealthy volunteers welcome
  • Mayo Clinic Florida, Jacksonville
Ages 18 and older · All sexes · Updated Feb 12, 2026 · NCT06262126

Lung Ultrasound Artefact Analysis for Exclusion of Acute Rejection in Lung Transplant Recipients

RecruitingHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT04582279

Study of Human Brain-Gut Axis and Gut Microbiome in Patients With Brain Lesions - Repository for Neuroscience Research

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT06117930

Building Community Living Labs in Black Communities to Advance Prostate Health Equity and Reduce Prostate Cancer Disparities in Black Men

RecruitingHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 21 to 80 · All sexes · Updated Jan 20, 2026 · NCT06541210

Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 18 and older · All sexes · Updated Dec 16, 2025 · NCT05116943

Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease

RecruitingPhase 4Healthy volunteers welcome
  • Mayo Clinic, Jacksonville
Ages 60 and older · Women · Updated Nov 24, 2025 · NCT03821857

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

RecruitingObservational studyHealthy volunteers welcome
  • Mayo Clinic, Jacksonville
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05137665

Understanding of Genetics by Men at Risk for Prostate Cancer

RecruitingHealthy volunteers welcome
  • Mayo Clinic in Florida, Jacksonville
Ages 40 to 95 · Men · Updated Nov 6, 2025 · NCT04550845

Accelerated Resolution Therapy for Early Maladaptive Grief

RecruitingHealthy volunteers welcome
  • Mayo Clinic Florida, Jacksonville
Ages 60 and older · All sexes · Updated Sep 25, 2025 · NCT05624879

Florida Community-Engaged Research Alliance (FL-CEAL)

RecruitingHealthy volunteers welcome
  • Mayo Clinic Florida Comprehensive Cancer Center, Jacksonville
Ages 13 and older · All sexes · Updated Sep 11, 2025 · NCT06829485

Non-invasive Nerve Stimulation for PTSD and Sleep

RecruitingHealthy volunteers welcome
  • UF Health Jacksonville, Jacksonville
Ages 18 to 55 · All sexes · Updated Jul 1, 2025 · NCT03170440

Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers

RecruitingPhase 1/2Healthy volunteers welcome
  • Mayo Clinic Jacksonville, Jacksonville
Ages 18 to 80 · All sexes · Updated May 2, 2025 · NCT05395624

The ME&MG Digital Solution for Autonomous Assessment of Myasthenia Gravis

RecruitingHealthy volunteers welcome
  • University of Florida Health, Jacksonville
Ages 18 and older · All sexes · Updated Apr 11, 2025 · NCT05564936

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.